A5019595743- Neurological Disorders and Treatments
- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Botulinum Toxin and Related Neurological Disorders
- Neonatal and fetal brain pathology
- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- EEG and Brain-Computer Interfaces
- Blood Coagulation and Thrombosis Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Genetic Neurodegenerative Diseases
- Human Health and Disease
- Neurological disorders and treatments
- Medical and Biological Sciences
- S100 Proteins and Annexins
- Infant Health and Development
- Infant Development and Preterm Care
- Bacteriophages and microbial interactions
- Pharmacological Effects and Toxicity Studies
- Pain Mechanisms and Treatments
- Microbial infections and disease research
- Alcoholism and Thiamine Deficiency
- Medical research and treatments
- Genomics and Rare Diseases
- Transactional Analysis in Psychotherapy
Ural State Medical University
2020-2025
City Clinical Hospital No. 2
2021-2025
Ural Federal University
2015-2025
Mental Health Research Center of Russian Academy of Medical Sciences
2021
Children's City Clinical Hospital №11
2016-2019
University of Pennsylvania
2018
City Clinical Hospital
2017
Pavlov Institute of Physiology of the Russian Academy of Sciences
1992
Dysphagia and sialorrhea are common complications of stroke that worsen quality life increase the risk aspiration pneumonia. Botulinum toxin type A (BoNT-A) injections effective in treatment sialorrhea, but there few data on use botulinum patients with dysphagia acute stroke. Objective : to evaluate efficacy safety incobotulinumtoxin prevention pneumonia ischemic Material methods . Twenty-seven were included study. All received an ultrasound-guided injection a total dose 100 units, divided...
To analyze the effectiveness of Relatox (Botulinum toxin type A - hemagglutinin complex) in comparison with Botox treatment primary idiopathic blepharospasm. The study included clinical data for 21 patients blepharospasm who were treated by botulinum therapy and 3 years. research method is a one-step retrospective analysis medical data. Injections carried out 3-month interval. On 6th cycle, drug was switched to Relatox. efficacy drugs assessed using an 8-point Jankovich evaluation scale:...
Objective. To develop criteria for prognosis of the outcome ischemic stroke, taking into account age, dynamics state assessment, Rankin and NIHSS scales readings fact disability in long-term period. The universal reliable criteria, that allow to predict have not been developed yet. Material methods. study group consisted 246 patients with stroke aged 18 44 who were observed from 2008 2021. Results. It is impossible a period reliably. Predicting using significant acute allows recovery mild...
The paper summarizes an update on the morbidity, mortality, and a risk for recurrence of stroke occurring in babies. It shows variety conditions syndromes which may be responsible infancy. Babies with signs intrauterine infection congenital heart disease, carriers major thrombophilia gene mutations, regarded as group.
Alcoholic polyneuropathy is a pressing problem in modern society. This neurological disease characterized by impaired functions of many peripheral nerves due to the toxic effects alcohol and its metabolites on nerve fibers. A study was conducted assess effectiveness use Gabapentin-SZ (North Star Co., Russia) polyneuropathy, involving 47 adult patients (31 men 16 women). The found significant efficacy treating pain with polyneuropathy. Significant improvement noted after 14 days therapy.
To determine clinical/instrumental predictors of symptomatic epilepsy after ischemic stroke in children.One hundred and thirty-six patients, aged 0-15 years, with the diagnosis (ICD-10 I63.0-I63.9) were examined. The duration study was 18 months - 12 years. Patients stratified into post-stroke (n=22) control (n=114) groups, latter included patients without regardless presence convulsive seizures acute stage stroke. Predictors determined based on EEG characteristics syndrome stroke.The...
Objective: to study the anamnestic, clinical and laboratory features of acute period ischemic stroke (IS) determine risk factors for its development in young patients. Patients methods. Clinical statistical processing data 256 patients aged 18 44 years included, who had IS, confirmed by computed and/or magnetic resonance imaging brain period, was carried out. Furthermore, 154 117 healthy participants, made up control group, eight polymorphisms thrombophilic spectrum genes were determined –...
OPINION article Front. Neurosci., 15 December 2022Sec. Neuroenergetics, Nutrition and Brain Health Volume 16 - 2022 | https://doi.org/10.3389/fnins.2022.1021035
Objective: to evaluate the safety, efficacy, and tolerability of botulinum toxin A Relatox® in arm hand spasticity after ischemic stroke routine clinical practice. Patients methods. The instigation enrolled 7 patients (7 years ago) with signs upper limb spasticity. All received combination treatment that involved daily kinesiotherapy sessions electrical stimulation paralyzed limbs. was once injected into forearm muscles 6 months or later stroke. Muscles were chosen according...