Abolfazl Zendehdel

ORCID: 0000-0003-2243-1912
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Helicobacter pylori-related gastroenterology studies
  • Sperm and Testicular Function
  • Eosinophilic Esophagitis
  • Blood groups and transfusion
  • Galectins and Cancer Biology
  • Vitamin D Research Studies
  • Renal Transplantation Outcomes and Treatments
  • Intestinal and Peritoneal Adhesions
  • Thermal Regulation in Medicine
  • Glutathione Transferases and Polymorphisms
  • Acute Kidney Injury Research
  • Neonatal Health and Biochemistry
  • Inflammatory Biomarkers in Disease Prognosis
  • COVID-19 diagnosis using AI
  • Health and Well-being Studies
  • Dialysis and Renal Disease Management
  • Pregnancy and Medication Impact
  • Selenium in Biological Systems
  • Pelvic floor disorders treatments
  • Sexual function and dysfunction studies
  • Pharmacological Receptor Mechanisms and Effects
  • Innovations in Medical Education
  • Empathy and Medical Education

Tehran University of Medical Sciences
2018-2025

North Khorasan University of Medical Sciences
2024

Kermanshah University of Medical Sciences
2024

Vitamin C is an essential water-soluble nutrient that functions as a key antioxidant and has been proven to be effective for boosting immunity. In this study, we aimed assess the efficacy of adding high-dose intravenous vitamin (HDIVC) regimens patients with severe COVID-19 disease.An open-label, randomized, controlled trial was conducted on infection. The case control treatment groups each consisted 30 patients. group received lopinavir/ritonavir hydroxychloroquine HDIVC (6 g daily) added...

10.1186/s40001-021-00490-1 article EN cc-by European journal of medical research 2021-02-11

The recent unprecedented pandemic caused by Sars-Cov-2 (the new coronavirus 2019), is threatening public health around the world. Although several studies have been performed, there no identified treatment for Covid-19 patients. Here we assessed efficacy of oseltamivir in combination therapy, comparing two different therapeutic regimens hospitalized patients, improving outcomes and find better patients.This a single-center retrospective cohort study 285 confirmed patients at (XXX). Depending...

10.1016/j.amsu.2022.103679 article EN Annals of Medicine and Surgery 2022-04-30

ABSTRACT Background and Aims it is important to identify patients at higher risk for severity poor outcomes of COVID‐19 infection, have better disease management pandemic control. In this study, we aimed assess the distribution ABO Rh blood groups in hospitalized infected demonstrate its association with disease. Methods This a cross‐sectional study Ziaeian Specialist Hospital, Tehran, Iran. Of all confirmed who were admitted hospital, 273 enrolled categorized based on their or clinical...

10.1002/hsr2.70250 article EN cc-by-nc-nd Health Science Reports 2025-02-01

Abstract Background and Aim Chemotherapy, particularly with methotrexate (MTX), often elicits testicular toxicity, leading to impaired spermatogenesis hormone imbalances. This study aimed investigate the potential protective effects of selenium (Se) against MTX‐induced injury. Materials Methods Male mice were divided into control, MTX, Se, MTX + Se groups. Histopathological examination involved preparation tissue sections using Johnsen's tubular biopsy score (JTBS) for evaluation....

10.1002/bdr2.2315 article EN Birth Defects Research 2024-02-01

Dialysis efficacy is one of the important issues in patients undergoing hemodialysis. This study aimed to determine adequacy dialysis with mortality and hospital admissions retrospective cohort was conducted on who underwent dialysis. measured based Kt/V criterion. Age, sex, disease etiology, duration dialysis, access were evaluated. 128 a mean age 61.48 ± 13.36 years included study. 8 had history kidney transplantation. The time 4.30 3.39 years. 1.40 1.8 Of patients, 53 hospitalized for...

10.1016/j.amsu.2022.103541 article EN Annals of Medicine and Surgery 2022-04-01

The quality and quantity of a spermatogonial stem-cell (SSC) culture can be measured in less time using 3D scaffold. present study investigated stemness gene expression the morphological structural characterization SSCs encapsulated alginate. were harvested from BALB/c neonatal mice testes through two-step mechanical enzymatic digestion. populations separated magnetic-activated cell sorting (MACS) an anti-Thy1 antibody c-Kit. then alginate hydrogel. After 2 months SSC culturing, microbeads...

10.1017/s0967199421000551 article EN Zygote 2021-10-13

Background: Immediate identification and treatment of patients at the risk developing sepsis would contribute to a more efficient diagnosis. This study aimed examine effective determinants bringing about rapid progression this disease towards septic shock severe sepsis. Materials Methods: is retrospective cross-sectional research on patients, above 12 years, admitted one hospitals in Tehran. It took 18 months conduct that included merely with Patients' cases were examined thoroughly,...

10.4103/atmph.atmph_646_17 article EN Deleted Journal 2017-01-01

Background and purpose: The recent unprecedented pandemic caused by Sars-Cov-2, is threatening public health over the world. Although several studies have been performed there no identified treatment for Covid-19 patients. Here we assessed efficacy of oseltamivir in combination therapy, comparing two different therapeutic regimens hospitalized Experimental approach: This a retrospective, according to date admission, patients were divided into groups; group 1 (oselta group) from Feb 20, 2020...

10.22541/au.170665561.10710656/v1 preprint EN Authorea (Authorea) 2024-01-30

Objective: The aim of this study is to evaluate and compare the clinical efficacy lopinavir/ritonavir with oseltamivir plus hydroxychloroquine for treatment Covid-19, in order find a better Covid-19 patients. Methods: In single-center, mixed designed cohort study, 198 patients admitted Ziaeian Hospital, Tehran, Iran were included. According date admission, received different treatments divided into two groups. Group 1 azithromycin whereas group 2 azithromycin. Patients’ outcomes measured...

10.22541/au.170664080.07159258/v1 preprint EN Authorea (Authorea) 2024-01-30

Background: In this study, we aimed to assess the prevalence of vitamin D deficiency in hospitalized Covid-19 patients and demonstrate its association with severity mortality disease. Methods: This observational study at Ziaeian Hospital, Tehran, Iran. Of all confirmed who were admitted hospital 276 enrolled divided into two groups; 145 group1 a serum 25(OH)D level >20 ng/ml 131 group 2 25 (OH)D =<20 ng/ml. The severity, outcome, disease compared these groups, based on chest CT scans...

10.22541/au.170663833.36455763/v1 preprint EN Authorea (Authorea) 2024-01-30

Background: it is important to identify patients at higher risk for severity and poor outcomes of Covid-19 infection, have better disease management pandemic control. In this study, we aimed assess the distribution ABO Rh blood groups in hospitalized infected demonstrate its association with disease. Methods: This a cross-sectional study Ziaeian specialist Hospital, Tehran, Iran. Off all confirmed who were admitted hospital, 273 enrolled categorized based on their or clinical including ICU...

10.22541/au.170663838.85503397/v1 preprint EN Authorea (Authorea) 2024-01-30

<title>Abstract</title> Objective: Considering the effects of vitamin D on inflammation and various infections, this study aims to determine if combining supplements with anti-Helicobacter pylori antibiotic treatment can improve eradication Helicobacter infection. Method This was conducted as a randomised clinical trial (RCT) 110 patients over 18 years age At beginning study, each patient received an oral supplement 50,000 units weekly, while in control group, placebo supplement.After 6...

10.21203/rs.3.rs-4917165/v1 preprint EN cc-by Research Square (Research Square) 2024-10-07

Background: DNA oxidation is one of the essential destructive effects reactive oxygen species (ROS) on cell membrane macromolecules leading to deformation cellular DNA. The most abundant oxidative product which studies have focused re-oxidized DNA, 8 oxo-deoxyguanosine (8-oxodG). This associated with various cancer initiation and progression. damage can be a marker including 8-oxodG, thymidine glycol, 8-oxoadenine, etc. affected by environmental non-environmental factors. Age, diet,...

10.18502/bccr.v13i4.14400 article EN cc-by-nc Basic & Clinical Cancer Research 2023-12-12
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