- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Urological Disorders and Treatments
- Urinary Tract Infections Management
- Anorectal Disease Treatments and Outcomes
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Hernia repair and management
- Pelvic and Acetabular Injuries
- Tissue Engineering and Regenerative Medicine
- Pediatric Urology and Nephrology Studies
- Pregnancy-related medical research
- Omental and Epiploic Conditions
- Urologic and reproductive health conditions
- Neuroscience and Neural Engineering
- Liver Disease and Transplantation
- Inflammatory mediators and NSAID effects
- Reproductive Health and Contraception
- Neonatal and fetal brain pathology
- Ureteral procedures and complications
- Traumatic Brain Injury Research
- Minimally Invasive Surgical Techniques
- Neuroscience and Neuropharmacology Research
- Genital Health and Disease
- Hormonal and reproductive studies
Taipei Medical University Hospital
2014-2024
Taipei Medical University
2015-2024
Taipei Hospital
2021
Chang Gung Memorial Hospital
2004-2018
Keelung Chang Gung Memorial Hospital
2012-2016
Memorial Hospital of South Bend
2006-2010
Chang Gung University
2010
The current treatment options for overactive bladder (OAB) continue to pose challenges refractory cases and may involve invasive procedures. To assess the potential benefit of non-invasive repetitive peripheral magnetic stimulation (rPMS) on sacral roots using intermittent theta burst (iTBS) as option OAB. study involved a total 33 rats, which were divided into three different experimental phases. induce overactivity rats pretreated with continuous transvesical infusion 0.5% acetic acid...
Abstract Aim: To evaluate the changes in symptoms of overactive bladder (OAB) on advanced cystocele after restoration prolapse using Perigee system. Methods: This prospective clinical study recorded 16 women for procedure due to with OAB symptoms. Prolapse assessment was measured according pelvic organ quantization Complete urodynamic examination performed before and six months operation. Subjects were also asked fill a questionnaire operation quantitative assay Additional reconstructive...
Abstract Interstitial cystitis/bladder pain syndrome (IC/BPS) negatively affects the quality of life. In this study, we investigated lifestyle behavioral changes patients with IC/BPS make to cope their symptoms. This prospective study was conducted between August 2018 and June 2019. All had a primary symptom suprapubic full bladder other lower urinary tract symptoms for more than 6 weeks as well cystoscopic findings. participants completed our self-developed questionnaire, which included...
To review and evaluate the potential adverse effects of these oral contraceptives (OCP) to overweight women. A 19-year-old college student, with a body mass index (BMI) 35.2 kg/m2, who received 2 months OCP containing cyproterone ethinyl estradiol for polycystic ovary syndrome (PCOS)-related menstrual problems was complicated thromboembolism-related life-threatened disease. After intensive care, including use an extracorporeal membrane oxygenation system, thrombolytic treatment,...
To evaluate the safety and efficacy of a combined laparoscopic vaginal approach through anterior cul-de-sac in dealing with fundal and/or wall uterine myomata.Seven women symptomatic myomata were enrolled this study. After identification location myomata, guiding suture brought dominant myoma down into vagina via an colpotomy. Resection suturing then performed transvaginally.Mean +/- standard deviation (SD) operative time, blood loss, length hospital stay 88.1 27.8 minutes, 278.6 131.8 mL,...
Pregnancy and childbirth are frequently associated with overactive bladder syndrome (OAB). However, the role of parous effects in OAB among nulliparous (NP) women remains controversial.This study investigated abnormal voiding patterns detrusor overactivity (DO) NP comparison women. From August 2011 to December 2018, 906 patients met inclusion criteria for participation were divided into three groups: 221 group, 571 normal spontaneous delivery (NSD) 114 cesarean section (CS) group. Urodynamic...
Overactive bladder (OAB) and interstitial cystitis/painful syndrome (IC/PBS) are 2 lower urinary tract disorders with urgency pain for diagnosis several other shared symptoms. Because of their overlapping symptoms, precise differential OAB IC/PBS remains difficult. Thus, we characterize a subgroup (OAB-BP) that can be differentiated from alone by urodynamic study (UDS) findings. We also further examined the clinical presentations parameters alone, OAB-BP, IC/PBS. Data were collected between...
Traumatic brain injuries (TBIs) are a serious public health issue worldwide with increased mortality as well severe disabilities and caused by falls road accidents. Unfortunately, there is no approved therapy for TBIs, bladder dysfunction striking symptom. Accordingly, we attempted to analyze voiding efficiency in rats TBI at different time-course intervals. Time-dependent analyses were scheduled from the next day until four weeks after TBI. Experimental animals grouped analyzed under above...
Interstitial cystitis/bladder pain syndrome (IC/BPS) is not only a chronic urinary bladder but also associated with multifactorial etiology. Our study aimed to test the hypothesis that IC/BPS subsequent increased risks of outpatient visits and hospitalizations. Using nationwide database, diagnoses were based on International Classification Codes (ICD-9-CM) (595.1) at least three services during 2002-2008, (n = 27,990) cystoscopic finding Hunner type and/or glomerulation pre-audit criteria....
Abstract Labial agglutination has rarely been reported in postmenopausal women and its treatment based on experience with prepubertal girls. We describe an 83‐year‐old woman who presented labial severe urinary incontinence. She had treated intermittently a topical estrogen cream for 3 years, but her symptoms persisted. Surgery was performed incontinence instantly resolved. Incidental vaginal low‐grade squamous intraepithelial neoplasia noted. Later, the lesion progressed confirmed to be...
Purpose:The aim of this study is to explore non-steroid anti-inflammation drugs (NSAIDs) potency for pelvic floor muscle pain by measuring local concentration in a rat model.Materials and Methods: We used nine NSAIDs, including nabumetone, naproxen, ibuprofen, meloxicam, piroxicam, diclofenac potassium, etodolac, indomethacin, sulindac, 9 groups female Wister rats.Each group rats was fed with one kind NSAID (2 mg/mL) three consecutive days.Thereafter, mL blood gram were taken measure drug...
Objective: Traumatic brain injuries (TBIs) are a prime public health challenge with high incidence of mortality, and also reflect severe economic impacts. One their symptoms is bladder dysfunction. Conventional therapeutic methods not effective in managing Henceforth, research endeavor was attempted to explore new approach for dysfunction through deep stimulation (DBS) procedures TBI animal model. Methods: this model induced by the weight-drop method. All rats an were housed 4 weeks allow...
The core objective of this study was to determine the neuroprotective properties deep brain stimulation pedunculopontine tegmental nucleus on apoptosis hippocampus. is a prime target for Parkinson′s disease and crucial component in feedback loop connected with Deep employed as potential tool evaluate hippocampal apoptosis. applied experimental animals an hour. Henceforth, activity Caspase-3, myelin basic protein, Bcl-2, BAX level, lipid peroxidation, interleukin-6 levels, brain-derived...
The aim of this study was to evaluate the efficacy uroflowmetry in predicting possibility abnormal voiding symptoms following antimuscarinic treatment for overactive bladder syndrome (OAB) Taiwanese women.A retrospective conducted on women with OAB. Forty-five patterns shown by urodynamic comprised main group and 38 normal control group. All patients were prescribed two mg tolterodine once daily one week. Follow-up complaints done week later.One woman 12 complained symptoms. There a...
Background: Managing chronic pelvic pain (CPP) remains a challenge due to its diverse range of causes. A newly identified anatomical entity known as the enthesis levator ani muscle (LAM) and associated disorders might play role. This paper describes novel insight into CPP’s origin, aiming improve accurate diagnosis treatment. Methods: Data were collected from medical records (paper or electronic) retrospectively. The study included 112 patients meeting criteria, divided CPP non-CPP groups....
To explore the relationship between overactive bladder (OAB) symptoms and paravaginal defects (PVDs), to identify necessity of PVD repair by transvaginal mesh (TVM) for treatment OAB symptoms.A retrospective clinical study 30 women with advanced cystocele limited apical posterior vaginal wall prolapse was conducted any changes in following a single Perigee procedure. Prolapse assessed using pelvic organ quantification (POP-Q) system, were identified sonography. Complete urodynamic...
To examine the alteration in cellular dynamics of urethral tissue after a simulated birth trauma mouse model.A total 36 B6 mice received vaginal distention treatment, and four untreated were used as controls. Specimens collected every 24 hours injury for 9 consecutive days examined using immunofluorescent staining cell markers including c-kit, smooth muscle actin (SMA), vimentin. Confocal microscopy was to localize stained cells determine number.The number c-kit positive increased 1st day...