A5047196112- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Lung Cancer Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Total Knee Arthroplasty Outcomes
- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Gastrointestinal disorders and treatments
- Orthopaedic implants and arthroplasty
- Cancer Immunotherapy and Biomarkers
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Head and Neck Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Knee injuries and reconstruction techniques
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Genetic factors in colorectal cancer
- Peptidase Inhibition and Analysis
- Cancer Treatment and Pharmacology
- Salivary Gland Tumors Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
Osaka International Cancer Institute
2016-2025
Iwate Medical University
2024
Onomichi General Hospital
2024
Hiroshima University
1972-2024
The Japanese Society of Gastroenterological Surgery
2024
National Institute of Diabetes and Digestive and Kidney Diseases
2019-2021
ProQuest (United States)
2019-2021
Tokai University Hachioji Hospital
2021
Bioengineering Center
2019
Osaka University
2008-2014
With endoscopy, there is a high rate of interobserver variability in the identification gastric intestinal metaplasia, and endoscopic findings correlate poorly with histological findings. Previous studies by our group investigating use narrow-band imaging system magnifying endoscopy (NBI-ME) mucosa suggested that appearance light blue crest (LBC) on epithelial surface may be distinctive finding associated presence metaplasia. The aim present study was to clarify value NBI-ME for diagnosing...
Long-term outcomes after endoscopic resection (ER) provide important information for the treatment of esophageal carcinoma. This study aimed to investigate rates survival and metastasis ER carcinoma.From 1995 2010, 570 patients with carcinoma were treated by ER. Of these, 402 squamous cell (280 epithelial (EP) or lamina propria (LPM) cancer, 70 muscularis mucosa (MM) 52 submucosal (SM) cancer) included in our analysis. Seventeen had cancer invading into submucosa up 0.2 mm (SM1) 35 more than...
With conventional methods of endoscopic mucosal resection for early gastric cancer (EGC), proton pump inhibitors (PPIs) and H2-receptor antagonists (H2RAs) have a similar effect on preventing bleeding from artificial ulcers. An objective this study is to investigate whether stronger acid suppressant (i.e., PPI) more effectively prevents after the recent advanced technique submucosal dissection (ESD) EGC.This was prospective randomized controlled trial performed in referral center. A total...
See also: Commentaire de travail Shunsuke Yamamoto et al., pp. 923Endoscopy 2009; 41(11): 1008-1008DOI: 10.1055/s-0032-1306751
Perforation is a major complication of endoscopic resection for gastrointestinal neoplasms. However, little known about delayed perforation after non-ampullary duodenal neoplasm. The aim the present study was to investigate clinical features neoplasm.This retrospective cohort conducted in referral cancer center. A total 63 patients (41 with adenomas and 22 carcinomas) underwent mucosal (EMR) or submucosal dissection (ESD) from January 1993 December 2011. Incidence, outcome, factors...
A cDNA library in X-phage Xgtll containing DNA inserts prepared from human liver mRNA was screened with monoclonal antibodies to protein C inhibitor.Six positive clones were isolated 6 X IO6 phages and plaque purified.The the phage largest insert, which hybridized a probe on basis of amino-terminal amino acid sequence mature inhibitor, sequenced.This insert contained 2106 base pairs coding for 5'-noncoding region, 19-amino signal peptide, 387-amino protein, stop codon, long 3"noncoding...
Endoscopic submucosal dissection (ESD) is a promising treatment for large gastrointestinal superficial neoplasms, although it technically difficult, and perforation delayed bleeding are well-known adverse events. However, there have been no studies about electrocoagulation syndrome after colorectal ESD. The aim of this study was to evaluate the incidence clinical significant risk factors post-ESD coagulation (PECS).This retrospective cohort conducted in referral cancer center. A total 336...
Narrow-band imaging (NBI) is a novel, noninvasive optical technique that uses reflected light to visualize the organ surface. However, few prospective studies examine efficacy of NBI screening for esophageal cancer have been reported. To compare diagnostic yield endoscopy squamous mucosal high-grade neoplasia esophagus between experienced and less endoscopists. Patients with history or head neck received endoscopic followed by chromoendoscopy using iodine staining. Biopsy specimens were...
OBJECTIVES: Chemoradiotherapy (CRT) has been proposed as an alternative therapy to esophagectomy for esophageal cancer, because of its favorable survival rate and mild toxicity. However, no comparative studies CRT have reported in patients with clinical stage I squamous cell carcinoma. METHODS: A total 54 carcinoma were treated definitive 116 at Osaka Medical Center Cancer Cardiovascular Diseases between 1995 2008, included the analysis. Overall recurrence rates evaluated. RESULTS: Complete...
The narrow band imaging classification system (NBI International Colorectal Endoscopic [NICE] classification) classifies colorectal polyps very accurately. However, sessile serrated adenoma/polyps (SSA/Ps) pathologically resembles hyperplastic polyp and has a possibility to be left in situ on NICE classification. aim of this study was establish evaluate new simple diagnostic features for SSA/Ps using magnifying (M-NBI).We performed single-arm observational accuracy two stages, as follows:...
Summary Accumulation of plasma cells in the synovium is one diagnostic hallmarks histopathological manifestations rheumatoid arthritis (RA). This seems to be prominent even prior significant B cell infiltration and/or formation lymphoid follicles synovium. To clarify mechanism early accumulation, we examined situ expression chemokines and their receptors using synovial targeting biopsy specimens, which were obtained under arthroscopy from RA patients. By immunohistochemical staining, found...
Although narrow-band imaging (NBI) is used increasingly in clinical situations, the significance of each NBI finding has not been investigated. The primary endpoint present study was to identify significant findings diagnose esophageal mucosal high-grade neoplasia.Between August 2007 and January 2009, we detected 59 new superficial lesions. video images were recorded digitally. such as brownish dots (dilated intra-epithelial papillary capillary loop [IPCL]), tortuous IPCL, elongated caliber...
Abstract Background Cold snare polypectomy (CSP) to remove multiple duodenal adenomas (MDAs) in patients with familial adenomatous polyposis (FAP) could be an effective and less invasive method than more extensive surgery. The aim of the present study was determine safety this procedure. Methods This prospective exploratory included 10 consecutive FAP MDAs who underwent CSP for as many 50 adenomas. primary outcome incidence severe adverse events. Results were enrolled 332 CSPs from June 2016...
Background: Satisfactory intermediate and long-term results of periacetabular rotational osteotomy for early osteoarthritis secondary to dysplasia the hip have been reported patients in third fourth decades life. The purpose present study was examine usefulness acetabular older than forty-six years age. Methods: A retrospective review two groups who had treated with a conducted. group consisted twenty-four (twenty-six hips) early-stage mean age at time surgery 50.9 (range, fifty-eight years)...
OBJECTIVES: The reported 1- and 3-year overall survival rates after esophagectomy for stage I superficial esophageal squamous cell carcinoma (SESCC) are 95–97% 86%, those definitive chemoradiotherapy (CRT) 98% 89%, respectively. This study was performed to elucidate the efficacy safety of another treatment option SESCC: endoscopic resection (ER) followed by CRT. METHODS: We retrospectively reviewed survival, recurrence, grade ≥3 adverse events consecutive patients who refused underwent ER...