A5006795483- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Screening and Detection
- Pancreatic and Hepatic Oncology Research
- Amino Acid Enzymes and Metabolism
- Neuropeptides and Animal Physiology
- Photodynamic Therapy Research Studies
- Eosinophilic Esophagitis
- PI3K/AKT/mTOR signaling in cancer
- Genetic factors in colorectal cancer
- Cancer, Stress, Anesthesia, and Immune Response
- Digestive system and related health
- Drug Transport and Resistance Mechanisms
- Colorectal Cancer Surgical Treatments
- Medical Device Sterilization and Disinfection
- Lung Cancer Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Polyamine Metabolism and Applications
- Receptor Mechanisms and Signaling
- Colorectal Cancer Treatments and Studies
Itami City Hospital
1995-2025
Osaka International Cancer Institute
2013-2024
The Japanese Society of Gastroenterological Surgery
2015-2023
Iwate Medical University
2021-2023
Hudson Institute
2023
Hiroshima University Hospital
2023
Showa University
2021
Jikei University School of Medicine
2021
Osaka Prefectural Medical Center
2007-2019
Community Link
2018
In response to the rapid and wide acceptance use of endoscopic treatments for early gastric cancer, Japan Gastroenterological Endoscopy Society (JGES), in collaboration with Japanese Gastric Cancer Association (JGCA), has produced 'Guidelines ESD EMR Early Cancer', as a set basic guidelines accordance principles evidence-based medicine. These Guidelines cover present state knowledge are divided into following seven categories: Indications, Preoperative diagnosis, Techniques, Evaluation...
With endoscopy, there is a high rate of interobserver variability in the identification gastric intestinal metaplasia, and endoscopic findings correlate poorly with histological findings. Previous studies by our group investigating use narrow-band imaging system magnifying endoscopy (NBI-ME) mucosa suggested that appearance light blue crest (LBC) on epithelial surface may be distinctive finding associated presence metaplasia. The aim present study was to clarify value NBI-ME for diagnosing...
Primary culture of the cancer cells from patients’ tumors can provide crucial information individual tumors, yet technology has not been optimized until now. We developed an innovative method for primary colorectal cells, based on principle that cell–cell contact was maintained throughout process. When tumor tissue dissociated into cell clusters, in which retained, they rapidly formed spheroids we termed tissue-originated (CTOSs). CTOSs consisted highly purified and viable were prepared with...
Synchronous occurrence of intraductal papillary mucinous neoplasm (IPMN) and ductal carcinoma the pancreas has been reported. Branch duct IPMNs with lower likelihood malignancy are not submitted to resection but followed-up, so may develop during follow-up. The development follow-up branch was investigated.60 patients IPMN who had an tumour <10 mm on imaging examinations a negative result for cytological examination pancreatic juice were investigated. They followed-up mainly by...
OBJECTIVES: Conventional endoscopic resection (CER) is a widely accepted treatment for early colorectal neoplasia; however, large neoplasias remain problematic, as they necessitate piecemeal resection, increasing the risk of local recurrence. Endoscopic submucosal dissection (ESD) can improve theen blocresection rate. This study aimed to evaluate recurrence and its associated factors after (ER) ≥20 mm. METHODS: A multicenter prospective at 18 medium- high-volume specialized institutions was...
Long-term outcomes after endoscopic resection (ER) provide important information for the treatment of esophageal carcinoma. This study aimed to investigate rates survival and metastasis ER carcinoma.From 1995 2010, 570 patients with carcinoma were treated by ER. Of these, 402 squamous cell (280 epithelial (EP) or lamina propria (LPM) cancer, 70 muscularis mucosa (MM) 52 submucosal (SM) cancer) included in our analysis. Seventeen had cancer invading into submucosa up 0.2 mm (SM1) 35 more than...
<b>Background and study aims: </b>The frequency of stricture after endoscopic submucosal dissection (ESD) for esophageal squamous cell carcinoma with a mucosal defect involving more than three-quarters the circumference is 70 % – 90 %. Stricture decreases quality life requires multiple balloon dilation (EBD) sessions. We investigated efficacy safety single session intralesional steroid injections to prevent post-ESD stricture. <b>Patients methods: </b>We conducted prospective on 30 patients...
With conventional methods of endoscopic mucosal resection for early gastric cancer (EGC), proton pump inhibitors (PPIs) and H2-receptor antagonists (H2RAs) have a similar effect on preventing bleeding from artificial ulcers. An objective this study is to investigate whether stronger acid suppressant (i.e., PPI) more effectively prevents after the recent advanced technique submucosal dissection (ESD) EGC.This was prospective randomized controlled trial performed in referral center. A total...
See also: Commentaire de travail Shunsuke Yamamoto et al., pp. 923Endoscopy 2009; 41(11): 1008-1008DOI: 10.1055/s-0032-1306751
Perforation is a major complication of endoscopic resection for gastrointestinal neoplasms. However, little known about delayed perforation after non-ampullary duodenal neoplasm. The aim the present study was to investigate clinical features neoplasm.This retrospective cohort conducted in referral cancer center. A total 63 patients (41 with adenomas and 22 carcinomas) underwent mucosal (EMR) or submucosal dissection (ESD) from January 1993 December 2011. Incidence, outcome, factors...
Bleeding, perforation, and residual/local recurrence are the main complications associated with colonoscopic treatment of colorectal tumor. However, current status regarding average incidence these in Japan is not available. We conducted a questionnaire survey, prepared by Colorectal Endoscopic Resection Standardization Implementation Working Group, Japanese Society for Cancer Colon Rectum (JSCCR), to clarify postoperative bleeding, treatment. The total bleeding was 1.2% 0.26% hot biopsy,...
Objectives A Japanese multicenter prospective cohort study examining endoscopic resection ( ER ) for early gastric cancer EGC has been conducted using a Web registry developed to determine the short‐term and long‐term outcomes based on absolute expanded indications. We hereby present of this study. Methods All consecutive patients with or suspected undergoing at 41 participating institutions between July 2010 June 2012 were enrolled prospectively registered into registry. The baseline...
Background and Aim Colorectal endoscopic submucosal dissection (ESD) remains challenging because of technical difficulties, long procedure time, high risk adverse events. To facilitate colorectal ESD, we developed traction‐assisted ESD using a clip thread (TAC‐ESD) conducted randomized controlled trial to evaluate its efficacy. Methods Patients with superficial neoplasms (SCN) ≥20 mm were enrolled randomly assigned the conventional‐ESD group or TAC‐ESD group. SCN ≤50 treated by two...
Abstract Background and study aim Underwater endoscopic mucosal resection (UEMR) was recently developed in a Western country. A prospective cohort to investigate the effectiveness of UEMR conducted patients with small superficial nonampullary duodenal adenomas. Patients methods adenomas ≤ 20 mm were enrolled. After lumen had been filled physiological saline, performed without submucosal injection. Endoclip closure attempted for all defects after UEMR. Follow-up endoscopy biopsy 3 months...
Endoscopic submucosal dissection (ESD) is a promising treatment for large gastrointestinal superficial neoplasms, although it technically difficult, and perforation delayed bleeding are well-known adverse events. However, there have been no studies about electrocoagulation syndrome after colorectal ESD. The aim of this study was to evaluate the incidence clinical significant risk factors post-ESD coagulation (PECS).This retrospective cohort conducted in referral cancer center. A total 336...