A5002136531- Inhalation and Respiratory Drug Delivery
- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Infection Control and Ventilation
- COVID-19 Clinical Research Studies
- Cardiac Arrest and Resuscitation
- Neonatal Respiratory Health Research
- SARS-CoV-2 and COVID-19 Research
- Intensive Care Unit Cognitive Disorders
- Nosocomial Infections in ICU
- Air Quality and Health Impacts
- Airway Management and Intubation Techniques
- Long-Term Effects of COVID-19
- Aerosol Filtration and Electrostatic Precipitation
- COVID-19 and healthcare impacts
- Immune responses and vaccinations
- COVID-19 epidemiological studies
- Air Quality Monitoring and Forecasting
- Sepsis Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Exercise and Physiological Responses
- Kidney Stones and Urolithiasis Treatments
- Restraint-Related Deaths
- Acute Kidney Injury Research
Beni-Suef University
2017-2025
Hospital General Universitario Morales Meseguer
2020
Hôtel-Dieu de Paris
2006
Abstract Coronavirus disease 2019 (COVID‐19) has had different waves within the same country. The spread rate and severity showed properties COVID‐19 waves. present work aims to compare of using available data confirmed cases death cases. Real‐data sets collected from Johns Hopkins University Center for Systems Science were used perform a comparative study between in 12 countries with highest total performed tests severe acute respiratory syndrome coronavirus 2 detection world (Italy,...
Predosing patients with COPD salbutamol by using a pressurized metered-dose-inhaler (pMDI) as bronchodilator was hypothesized to improve the distribution of subsequent nebulized dose. This study determined effect pMDI preliminary dose on aerosol delivered mesh nebulizer during single-limb noninvasive ventilation.Twelve subjects who received ventilation were enrolled in randomized, open-label, urinary pharmacokinetic study. A bi-level ventilator dry circuit and fixed expiratory port set...
Background: There is a lack of guidance on inhaler device selection and how to individualize choice when prescribed for the first-time.Aim work: To compare different inhalers regarding ease use number counseling attempts needed correct handling in subjects with first experience such inhalers; also, investigate if there correlation between total steps achievements patient demographics/clinical variables.Method: An open-label, non-drug interventional, cross-over study was conducted including...
Abstract Backgrounds SARS‐CoV‐2 is affecting different countries all over the world, with significant variation in infection‐rate and death‐ratio. We have previously shown a presence of possible relationship between variables including Bacillus Calmette–Guérin (BCG) vaccine, average age, gender, malaria treatment, rate spread, severity mortality COVID‐19 disease. This paper focuses on developing machine learning models for this relationship. Methods used real‐datasets collected from Johns...
This systematic review aimed to investigate the drugs used and their potential effect on noninvasive ventilation (NIV).NIV is increasingly in acute respiratory failure (ARF). Sedation analgesia are potentially beneficial NIV, but they can have a deleterious impact. Proper guidelines specifically address this issue recommendations for or against it scarce literature. In most recent published 2017 by European Respiratory Society/American Thoracic Society (ERS/ATS) relating NIV use patients...
The effectiveness of the best combination between different antiviral and anti-inflammatory drugs stills an interest in treatment COVID19 infection.A prospective randomized cohort study comprised 108 adult patients with confirmed PCR COVID 19 infection systemic hyper inflammation state, divided into two groups according to regimen, 56 tocilizumab- hydroxychloroquine (TCZ-HCQ) treatment, 52 tocilizumab-remdesivir (TCZ-RMV) treatment. first group received a I.V. TCZ (400-800 mg every 24 h for...
There is a lack of an overview determinants incorrect inhaler technique among chronic obstructive pulmonary diseases (COPD) subjects. The aim this study was to determine the prevalence and possible in COPD subjects with common inhalers.A cross over conducted 180 Baseline assessment evaluated 10 placebo inhalers including: [pressurised metered dose (pMDI), Aerolizer, Handihaler, Turbohaler, Discus, Breezhaler, Ellipta, Easyhaler, Diskhaler Respimat] without receiving any instructions....
Purpose This study aimed to evaluate handling of six common inhalers and determine correlations between correct inhaler technique patient demographics/ clinical variables. Methods A total 180 chronic obstructive pulmonary disease (COPD) patients were crossed-over handle their past-experienced among (pMDI, Aerolizer, Handihaler, Breezhaler, Turbohaler, Diskus) randomly, without receiving verbal or demonstrative instruction (baseline assessment). Inhaler was assessed using previously defined...
Abstract The objective of this study was to assess the use pMDI alone and with different spacers in asthmatic patients identify any associations between errors handling device for first time sessions needed reach correct method, considering patient demographics clinical characteristics. A total 150 Asthmatic were crossed over handle add-on inhalable devices (Aerochamber plus, Tips Haler, Able, Dispozable Aer-8) randomly, without receiving verbal or demonstrative instruction (baseline...
Introduction Aerosol delivery from DPIs could be affected by different factors. This study aimed to evaluate and predict the effects of factors on drug DPIs. Methods Modelling optimisation for both in vitro vivo data (Diskus, Turbohaler Aerolizer) were carried out using neural networks associated with genetic algorithms results are confirmed a decision tree (DT) random forest regressor (RFR). All variables (the type DPI, inhalation flow, volume, number inhalations subject) coded as numbers...
Objectives: This study aimed to evaluate the effect of a preliminary bronchodilator dose on aerosol-d elivery by different nebulizers in noninvasively ventilated chronic obstructive pulmonary disease (COPD) patients. Method: COPD patients were randomized receive doses 800 µg beclomethasone dipropionate (BPD) nebulized either vibrating mesh nebulizer (VMN) or jet (JN) connected MinimHal spacer device. On day, was given each patient same aerosol generator with and without preceded two puffs...
High-flow nasal cannula oxygen therapy (HFNCOT) system consists of an air/oxygen supply capable delivering up to 100% humidified and heated at a flow rate 80 L/min. The includes blender, active humidifier, single tube, cannula. HFNCOT has many physiological advantages compared with other standard therapies, such as anatomical dead space washout, more constant fraction inspired oxygen, positive end-expiratory (PEEP) effect, supplement adequate humidification maintenance muco-ciliary function....