Organocatalysis is an emerging and new field towards the direction of asymmetric synthesis has shown a tremendous growth in 21st century. As demand for chiral pharmaceuticals organic molecules increasing immensely, different types organocatalysts have been developed used from time to time. The cinchona alkaloids amino acid proline were first this area followed by incredible form urea/thiourea, DMAP, derivatives, squaramides, peptides, etc. squaramide based are gaining impetus transformations...

We report a new family of chiral bifunctional acid/base type organocatalysts, 2-aminoDMAP/Squaramides, which are proved to be highly active (1 mol % cat. loading) promoters in conjugate addition dibenzoylmethane various trans-β-nitroalkenes. Steric demand the catalysts was clearly seen by set-by-set modulation squaramide unit through electronic and steric factors. The synergistic cooperation 2-aminoDMAP “superbase” sterically encumbered (H-bond donor) enabled complete conversion range...

Here we report the synthesis of a novel conducting polymer and its properties as an immobilization platform for biosensor application. The has functional groups used formation amide bonding with enzyme immobilized on surface. After covalent glucose oxidase (GOx) polymeric matrix, application biosensing was investigated in detail. Scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) contact angle measurements were to monitor surface before after biomolecule conjugation....

This work describes the development of first enantioselective addition reaction between 1,3,5,7-tetramethyl-BODIPYs and isatin derivatives. The utilizes bifunctional quinine/squaramide organocatalysts affords nine novel chiral BODIPY dyes under mild conditions, with enantioselectivities reaching up to 60%. synthesized BODIPY–oxindoles exhibit high fluorescence emissions, consistent their parent BODIPYs, display tunable colors. A representative example demonstrates a remarkably quantum yield...

Asymmetric organocatalysis by bifunctional acid- and base-type small organic molecules has emerged as a promising way to enhance stereoselective transformations since the beginning of this millennium. Takemoto's tert-amine/thiourea catalyst, an archetype in these endeavors, encouraged many design new multifunctional alternatives. However, discovery efficient catalysts library thousands candidates containing desired functionalities their structures remains great challenge both synthetically...

2-Adamantyl substituted quinine-squaramide catalyzed aza-Friedel–Crafts reaction of <italic>N</italic>-carbamate isatin ketimines with naphthol afforded chiral isatin-derived 1,3-aminonaphthols excellent enantioselectivity up to greater than 99% and quantitative yield.

Abstract The α-oxidation of aryl alkyl ketones using manganese(III) acetate in the presence various carboxylic acids and (1S)-(+)-10-camphorsulfonic acid provided a convenient synthesis α-acyloxy, α-(10-camphorsulfonyloxy), α-hydroxy derivatives good yield.

Abstract A copolymer of 1‐(4‐fluorophenyl)‐2,5‐di(thiophen‐2‐yl)‐1 H ‐pyrrole (FPTP) with 3,4‐ethylene dioxythiophene (EDOT) was electrochemically synthesized and characterized. While poly(FPTP) (P(FPTP)) has only two colors in its oxidized neutral states (blue yellow), EDOT five different (purple, red, light gray, green, blue). Electrochromic devices based on P(FPTP‐ co ‐EDOT) poly(3,4‐ethylenedioxythiophene) (PEDOT) were constructed The state the device shows blue color whereas it purple...

One of the obstructive problems luminogenic molecules is aggregation caused quenching (ACQ) and as a result they lose their emissive property when turn into solid from solution form. Therefore, there an increase in demand for having induced emission (AIE) property, opposite ACQ. Bright new molecules, tetraphenylethene (TPE) core anchored by indole (TIPE), tert-butylcarbazole (TTBCPE) tetrahydrocarbazole (TDCPE), were synthesized practically two steps without any expensive boronic acids or Pd...

Abstract A new polythiophene derivative was synthesized by both chemical and electrochemical oxidative polymerization of 1‐(1‐phenylethyl)‐2,5‐di(2‐thienyl)‐1 H ‐pyrrole (PETPy). Of which the method produces a polymer that is completely soluble in organic solvents. The structures monomer were elucidated nuclear magnetic resonance ( 1 13 C NMR) Fourier transform infrared (FTIR) spectroscopy. average molecular weight has been determined gel permeation chromatography to be M n = 3.29 × 10 3 for...