Nathan S. McClure

ORCID: 0000-0003-2273-1245
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Health Systems, Economic Evaluations, Quality of Life
  • Evolution and Genetic Dynamics
  • Forest Management and Policy
  • Economic and Environmental Valuation
  • Pharmaceutical Economics and Policy
  • Pharmaceutical Practices and Patient Outcomes
  • Animal Behavior and Reproduction
  • Primary Care and Health Outcomes
  • Antibiotic Use and Resistance
  • Aerospace Engineering and Control Systems
  • Environmental and Social Impact Assessments
  • Stroke Rehabilitation and Recovery
  • Healthcare Policy and Management
  • Diabetic Foot Ulcer Assessment and Management
  • Delphi Technique in Research
  • Zoonotic diseases and public health
  • Streptococcal Infections and Treatments
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Plant and animal studies
  • Healthcare Education and Workforce Issues
  • Computational Drug Discovery Methods
  • Wound Healing and Treatments
  • HIV/AIDS drug development and treatment
  • Acute Ischemic Stroke Management
  • Viral Infections and Vectors

University of Alberta
2017-2024

Institute of Health Economics
2022

Arizona State University
2019

Alliance for Canadian Health Outcomes Research in Diabetes
2019

Queen's University
2012-2014

Southern Research Station
2007

United States Department of Agriculture
2007

US Forest Service
2007

Drug resistance is a serious public health problem that threatens to thwart our ability treat many infectious diseases. Repeatedly, the introduction of new drugs has been followed by evolution resistance. In principle, there are two complementary ways address this problem: (i) enhancing drug development and (ii) slowing through evolutionary management. Although these strategies not mutually exclusive, it nevertheless worthwhile considering whether one might be inherently more effective than...

10.1098/rspb.2014.1861 article EN cc-by Proceedings of the Royal Society B Biological Sciences 2014-11-06

To estimate and compare the minimally important difference (MID) in index score of country-specific EQ-5D-5L scoring algorithms developed using EuroQol Valuation Technology protocol version 2, including from Germany, Indonesia, Ireland, Malaysia, Poland, Portugal, Taiwan, United States.A simulation-based approach contingent on all single-level transitions defined by descriptive system was used to MID for each algorithm.The resulting mean (and standard deviation) instrument-defined estimates...

10.1016/j.jval.2020.03.003 article EN cc-by Value in Health 2020-05-14

Background. Increasing demand for provision of care to stroke survivors creates challenges health planners. A key concern is the optimal alignment resources between acute care, rehabilitation, and among different segments including inpatient early supported discharge (ESD), outpatient rehabilitation (OPR). We propose a novel application discrete event simulation (DES) combined with genetic algorithm (GA) identify configuration that maximizes patient benefits subject finite resources. Design....

10.1177/23814683221134098 article EN cc-by-nc MDM Policy & Practice 2022-07-01

Drug resistance is a serious public health problem that threatens to thwart our ability treat many infectious diseases. Repeatedly, the introduction of new drugs has been followed by evolution resistance. In principle there are two ways address this problem: (i) enhancing drug development, and (ii) slowing We present data modeling approach based on queueing theory explores how interventions aimed at these facets affect entire supply system provide service. Analytical simulation-based results...

10.48550/arxiv.1304.7715 preprint EN other-oa arXiv (Cornell University) 2013-01-01

This study aims to determine how population-based health-utility score (HUS) differences reflect individuals' health preferences using responses from the Canadian EQ-5D-5L Valuation Study, including time trade-off (TTO) and discrete-choice experiment (DCE) tasks (n = 1073).Cardinal TTO were transformed into pairwise comparisons yield ordinal responses. We investigated HUS differ participants' stated cardinal preferences, determined smallest difference that may be expected represent...

10.1016/j.jclinepi.2021.10.019 article EN cc-by-nc-nd Journal of Clinical Epidemiology 2021-11-02
Coming Soon ...