Amy Dowden

ORCID: 0000-0003-2274-0782
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About
Contact & Profiles
Research Areas
  • Drug-Induced Adverse Reactions
  • Pharmacovigilance and Adverse Drug Reactions
  • Contact Dermatitis and Allergies
  • Biosimilars and Bioanalytical Methods
  • Eosinophilic Disorders and Syndromes
  • Antimicrobial Resistance in Staphylococcus
  • Medical Practices and Rehabilitation
  • Allergic Rhinitis and Sensitization
  • Antibiotics Pharmacokinetics and Efficacy
  • Urticaria and Related Conditions
  • Antifungal resistance and susceptibility
  • Electroconvulsive Therapy Studies
  • Muscle and Compartmental Disorders
  • Mesenchymal stem cell research
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Pneumonia and Respiratory Infections
  • Food Allergy and Anaphylaxis Research
  • Dermatology and Skin Diseases
  • Mast cells and histamine
  • Surgical Sutures and Adhesives
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Fungal Infections and Studies
  • Blood groups and transfusion
  • Dermatologic Treatments and Research

University of Iowa
2006-2025

University of Iowa Hospitals and Clinics
2005-2024

University of Iowa Health Care
2017

Veterans Health Administration
2007

Abstract Background: Concerns about penicillin-cephalosporin cross-reactivity have historically led to conservative prescribing and avoidance of cephalosporins in patients with penicillin allergy labels, potentially causing suboptimal outcomes. Recent evidence suggests a lower risk cross-reactivity, prompting reassessment alert systems. Objective: To assess the impact limited alerts on outpatient cephalosporin use incidence adverse reactions healthcare setting. Methods: This retrospective...

10.1017/ice.2025.9 article EN Infection Control and Hospital Epidemiology 2025-03-13

Membrane‐bound human leukocyte antigen‐G (HLA‐G) molecules are primarily expressed by cytotrophoblasts of the fetus. They thought to protect fetus from immunologic attack maternal immune system and have recently been associated with transplantation graft acceptance. In addition, soluble HLA‐G (sHLA‐G) shown play a role in success pregnancies, but upregulated certain cancers. However, exact mechanism for this regulation has remained elusive. The aim study was examine which sHLA‐G interact...

10.1111/j.1600-0897.2006.00395.x article EN American Journal of Reproductive Immunology 2006-05-17

Achieving transplantation tolerance remains an unresolved clinical challenge. Although bone marrow (BMT) induces mixed chimerism that establishes tolerance, the preconditioning regimens required for BMT to succeed are too prohibitive routine use. Recently, embryonic stem (ES) cells have emerged as a potential alternative cell source cells. However, it difficult efficiently differentiate these into hematopoietic Here, we tested whether morphogenetic protein-4 (BMP-4)-treated or...

10.1097/tp.0b013e31818fe741 article EN Transplantation 2008-12-15

10.1016/j.jaci.2023.11.516 article EN Journal of Allergy and Clinical Immunology 2024-02-01

Chlorhexidine gluconate (CHG) is a topical antiseptic and surgical scrub increasingly implicated in periprocedural anaphylaxis. We present four patients who had anaphylaxis the setting of CHG exposure, an agent that has been Catheters can be impregnated with overlooked as source exposure resulting

10.22541/au.172457260.02984274/v1 preprint EN Authorea (Authorea) 2024-08-25

10.1016/j.jaci.2006.12.153 article EN Journal of Allergy and Clinical Immunology 2007-01-01

10.1016/j.jaci.2005.12.1089 article EN Journal of Allergy and Clinical Immunology 2006-02-01
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