A5079110860- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Pharmacological Receptor Mechanisms and Effects
- Epilepsy research and treatment
- SARS-CoV-2 and COVID-19 Research
- Poxvirus research and outbreaks
- Respiratory Support and Mechanisms
- Healthcare Regulation
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Intensive Care Unit Cognitive Disorders
- Pharmacological Effects and Toxicity Studies
- COVID-19 and Mental Health
- Infectious Encephalopathies and Encephalitis
- Vector-Borne Animal Diseases
- Virus-based gene therapy research
- Youth, Drugs, and Violence
- PARP inhibition in cancer therapy
Pontifícia Universidade Católica de Minas Gerais
2021-2024
Universidade Federal de Minas Gerais
2010
Ministério da Saúde
2010
Fundação Oswaldo Cruz
2010
BackgroundRecent evidence indicates a potential therapeutic role of fluvoxamine for COVID-19. In the TOGETHER trial acutely symptomatic patients with COVID-19, we aimed to assess efficacy versus placebo in preventing hospitalisation defined as either retention COVID-19 emergency setting or transfer tertiary hospital due COVID-19.MethodsThis placebo-controlled, randomised, adaptive platform done among high-risk Brazilian adults confirmed positive SARS-CoV-2 included eligible from 11 clinical...
<h3>Importance</h3> Data on the efficacy of hydroxychloroquine or lopinavir-ritonavir for treatment high-risk outpatients with COVID-19 in developing countries are needed. <h3>Objective</h3> To determine whether reduces hospitalization among patients early symptomatic an outpatient setting. <h3>Design, Setting, and Participants</h3> This randomized clinical trial was conducted Brazil. Recently adults diagnosed respiratory symptoms from SARS-CoV-2 infection were enrolled between June 2...
Previous trials have demonstrated the effects of fluvoxamine alone and inhaled budesonide for prevention disease progression among outpatients with COVID-19. To determine whether combination would increase treatment in a highly vaccinated population. Randomized, placebo-controlled, adaptive platform trial. (ClinicalTrials.gov: NCT04727424). 12 clinical sites Brazil. Symptomatic adults confirmed SARS-CoV-2 infection known risk factor to severe disease. Patients were randomly assigned either...
Observational studies have postulated a therapeutic role of metformin in treating COVID-19. We conducted an adaptive platform clinical trial to determine whether is effective treatment for high-risk patients with early COVID-19 outpatient setting.The TOGETHER Trial placebo-controled, randomized, Brazil. Eligible participants were symptomatic adults positive antigen test SARS-CoV-2. enroled eligible over the age 50 years or known risk factor disease severity. Patients randomly assigned...
Vaccinia virus is responsible for a zoonosis that usually affects cattle and human beings in Brazil. The initial clinical signs of the infection are focal red skin areas, fever, general symptoms similar to those cold. Then, pustules ulcerated lesions surrounded by edema erythema follow, as well local lymphadenopathy can last weeks. Cure healing occur over several weeks, leaving typical scar people animals affected. definitive diagnosis made through morphological characterization use electron...
<ns3:p><ns3:bold>B</ns3:bold><ns3:bold>ackground: </ns3:bold>There remains a need for an effective and affordable outpatient treatment early COVID-19. Multiple repurposed drugs have shown promise in treating We describe master protocol that will assess the efficacy of different as treatments COVID-19 among outpatients at high risk severe complications.</ns3:p><ns3:p> <ns3:bold>Methods: </ns3:bold>The TOGETHER Trial is multi-center platform adaptive randomized, placebo-controlled, clinical...
ABSTRACT Background Recent evidence indicates a potential therapeutic role of fluvoxamine for COVID-19. In the TOGETHER randomized platform clinical trial acutely symptomatic patients with COVID-19, we assessed efficacy vs. placebo in preventing either extended emergency room observation or hospitalization due to Herein, report preliminary findings. Methods This placebo-controlled, randomized, adaptive, conducted among Brazilian adults confirmed positive SARS-CoV-2 included eligible known...
<ns3:p><ns3:bold>Background: </ns3:bold>Although vaccines are currently available for coronavirus disease 2019 (COVID-19), there remains a need an effective and affordable outpatient treatment early COVID-19. Multiple repurposed drugs have shown promise in treating We describe master protocol that will assess the efficacy of different as treatments COVID-19 among outpatients at high risk severe complications.</ns3:p><ns3:p> <ns3:bold>Methods: </ns3:bold>The TOGETHER Trial is international...
Este artigo apresenta resultados de um rastreamento funcionários supermercado Belo Horizonte, a fim identificar indivíduos com níveis glicêmicos e pressóricos alterados. A atividade foi realizada em dois momentos participaram 46 funcionários. No primeiro momento, aplicado questionário, mensurados dados antropométricos aferição pressão arterial glicemia capilar; no segundo, houve apresentação dos aos os mesmos foram orientados quanto hábitos vida saudáveis. Observaram-se casos obesidade,...