A5048125439- Hip and Femur Fractures
- Bone fractures and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Pelvic and Acetabular Injuries
- Orthopaedic implants and arthroplasty
- Trauma and Emergency Care Studies
- Intimate Partner and Family Violence
- Meta-analysis and systematic reviews
- Health Systems, Economic Evaluations, Quality of Life
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Surgical site infection prevention
- Bone health and osteoporosis research
- Hip disorders and treatments
- Sexual Assault and Victimization Studies
- Shoulder Injury and Treatment
- Health and Medical Research Impacts
- Orthopedic Surgery and Rehabilitation
- Elder Abuse and Neglect
- Healthcare cost, quality, practices
- Clinical practice guidelines implementation
- Child Abuse and Trauma
- Health Sciences Research and Education
- Knee injuries and reconstruction techniques
- Sports injuries and prevention
McMaster University
2016-2025
Impact
2017-2025
University of Maryland, Baltimore
2015-2024
Patient-Centered Outcomes Research Institute
2024
Bruyère
2024
St Michael’s Hospital
2024
University of Ottawa
2017-2024
Children's Hospital of Eastern Ontario
2024
Université de Sherbrooke
2024
Intensive Care National Audit & Research Centre
2024
BackgroundRecent evidence indicates a potential therapeutic role of fluvoxamine for COVID-19. In the TOGETHER trial acutely symptomatic patients with COVID-19, we aimed to assess efficacy versus placebo in preventing hospitalisation defined as either retention COVID-19 emergency setting or transfer tertiary hospital due COVID-19.MethodsThis placebo-controlled, randomised, adaptive platform done among high-risk Brazilian adults confirmed positive SARS-CoV-2 included eligible from 11 clinical...
The efficacy of ivermectin in preventing hospitalization or extended observation an emergency setting among outpatients with acutely symptomatic coronavirus disease 2019 (Covid-19), the caused by severe acute respiratory syndrome 2 (SARS-CoV-2), is unclear.We conducted a double-blind, randomized, placebo-controlled, adaptive platform trial involving SARS-CoV-2-positive adults recruited from 12 public health clinics Brazil. Patients who had symptoms Covid-19 for up to 7 days and at least one...
The efficacy of a single dose pegylated interferon lambda in preventing clinical events among outpatients with acute symptomatic coronavirus disease 2019 (Covid-19) is unclear.
Studies evaluating surgical-site infection have had conflicting results with respect to the use of alcohol solutions containing iodine povacrylex or chlorhexidine gluconate as skin antisepsis before surgery repair a fractured limb (i.e., an extremity fracture).
Background The assessment of fracture healing is both a clinically relevant and frequently used outcome measure following lower extremity trauma. However, it remains uncertain whether there consensus in the among orthopaedic surgeons. Variability may have important implications surgeons' decisions to intervene when they perceive slow progress. Objective To identify approaches tibial definitions delayed union, nonunion, malunion Study Design Cross-sectional survey 577 Methods Focus groups,...
Background: Oral presentations at national and international meetings offer an excellent forum for the dissemination of current research findings. However, publication rates full-text articles after presentation abstracts have ranged from 11% to 78%, which suggests that least 32% presented are never published as complete in peer-reviewed journals. In effort identify reasons surgeons had not a paper following their work orthopaedic meeting, we conducted survey cross section authors papers...
Research abstracts are frequently referenced in orthopaedic textbooks and influence care. However, little is known about the quality of information provided abstracts, frequency publication complete papers after presentation or any discrepancies between published papers. The objective this study was to determine rates full-text articles predictors articles, consistency articles.We retrieved all from 1996 scientific program sixty-third Annual Meeting American Academy Orthopaedic Surgeons. For...
The purpose of this study was threefold: (1) to determine the scientific quality published randomized trials in American Volume Journal Bone and Joint Surgery from 1988 through 2000, (2) identify predictors quality, (3) evaluate inter-rater agreement scoring with use a simple scale.Hand searches were conducted duplicate clinical trials. Of 2468 studies identified, seventy-two (2.9%) met all eligibility criteria. Two investigators each assessed under blinded conditions abstracted relevant...
Background Accurate prediction of likelihood reoperation in patients with tibial shaft fractures would facilitate optimal management. Previous studies were limited by small sample sizes and noncomprehensive examination possible risk factors. Objective We conducted an observational study to determine which prognostic factors associated increased following operative treatment a heterogeneous population fractures. Design Retrospective study. Setting Level 1 trauma center. Methods identified 200...
Low response rates among surgeons can threaten the validity of surveys. Internet technologies may reduce time, effort, and financial resources needed to conduct surveys.We investigated whether using Web-based technology could increase an international survey.We solicited opinions from 442 surgeon-members Orthopaedic Trauma Association regarding treatment femoral neck fractures. We developed a self-administered questionnaire after conducting literature review, focus groups, key informant...
Abstract Background Tibial shaft fractures are the most common long bone fracture and prone to complications such as nonunion requiring reoperations promote healing. We aimed determine characteristics associated with tibial nonunion, their predictive value on need for reoperation. further evaluate of a previously-developed prognostic index three reoperation rate. Methods conducted an observational study developed risk factor list from previous literature key informants in field orthopaedic...
Radiographic assessment of tibial fracture healing continues to pose significant challenges both routine care and clinical research. Orthopaedic surgeons fail achieve sufficient agreement on when using conventional radiographic measures such as their general impression or the number cortices bridged by callus. Moreover, extent which corresponds patient-important outcomes is largely unknown. In an attempt improve former (ie, reliability) inform latter validity), recent studies have explored a...
Background: Despite the large number of fracture outcome studies, there remains variability in definitions fracture-healing. It is unclear how orthopaedic surgeons are diagnosing and managing delayed unions nonunions clinical practice. We aimed to explore current opinions with regard defining, diagnosing, treating extremity fractures. Methods: developed a survey using previous literature, key informants field surgery, sample-to-redundancy strategy. Our final contained four sections...