Thomas F. Higgins

ORCID: 0000-0003-4679-8583
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About
Contact & Profiles
Research Areas
  • Bone fractures and treatments
  • Hip and Femur Fractures
  • Orthopedic Surgery and Rehabilitation
  • Pelvic and Acetabular Injuries
  • Trauma and Emergency Care Studies
  • Orthopaedic implants and arthroplasty
  • Foot and Ankle Surgery
  • Total Knee Arthroplasty Outcomes
  • Knee injuries and reconstruction techniques
  • Orthopedic Infections and Treatments
  • Surgical site infection prevention
  • Shoulder Injury and Treatment
  • Cardiac, Anesthesia and Surgical Outcomes
  • Sports injuries and prevention
  • Spinal Fractures and Fixation Techniques
  • Transplantation: Methods and Outcomes
  • Diabetic Foot Ulcer Assessment and Management
  • Elbow and Forearm Trauma Treatment
  • Pain Management and Opioid Use
  • Anesthesia and Pain Management
  • Trauma Management and Diagnosis
  • Tendon Structure and Treatment
  • Opioid Use Disorder Treatment
  • Radiation Dose and Imaging
  • Shoulder and Clavicle Injuries

University of Utah
2016-2025

Baystate Medical Center
2008-2025

University of Maryland, Baltimore
1999-2024

Population Health Research Institute
2024

Hamilton Health Sciences
2024

McMaster University
2024

Orthopaedic Trauma Association
2015-2023

Arthritis Foundation
2023

National Cancer Registration Service
2023

Harborview Medical Center
2023

Purpose: Patient-reported outcomes are important to assess effectiveness of clinical interventions. For orthopaedic trauma patients, the short Musculoskeletal Function Assessment (sMFA) is a commonly used questionnaire. Recently, Patient-Reported Outcome Measurement Information System (PROMIS) PF Computer Adaptive Test (PF CAT) was developed using item response theory efficiently administer questions from calibrated bank 124 computerized adaptive testing. In this study, we compared sMFA...

10.1097/bot.0000000000000059 article EN Journal of Orthopaedic Trauma 2013-12-30

Studies evaluating surgical-site infection have had conflicting results with respect to the use of alcohol solutions containing iodine povacrylex or chlorhexidine gluconate as skin antisepsis before surgery repair a fractured limb (i.e., an extremity fracture).

10.1056/nejmoa2307679 article EN New England Journal of Medicine 2024-01-31

Background: The purpose of this study was to compare the outcomes surgical treatment in children walking age with unilateral and bilateral developmental dysplasia hip (DDH). Methods: We examined records fifty-six 156 treated open reduction pelvic osteotomy or without femoral from 1990 2000. minimum duration follow-up five years. mean at surgery thirty-four months group twenty-five group. Preoperative radiographs were evaluated determine Tönnis grade dislocation acetabular index, latest...

10.2106/jbjs.l.00619 article EN Journal of Bone and Joint Surgery 2013-06-01

Further data are presented concerning the unusual hemodynamic effects of 1-hydrazinophthalazine. Previous observations demonstrating a marked increase in cardiac output normotensive subjects confirmed hypertensive patients. The splanchnic vascular bed is one sites increased blood flow. similarity between 1-hydrazinophthalazine and pyrogens pointed out pharmacologic basis for clinically observed additive hexamethonium discussed.

10.1161/01.cir.8.2.199 article EN Circulation 1953-08-01

Bicondylar tibial plateau fractures featuring extensive articular involvement have a record of mixed clinical results. Recent discussion has focused on the significance posteromedial fragment in bicondylar injuries. This often gone unrecognized or not been addressed. The is defined as any posteriorly based fracture medial with line exiting cortex. study designed to produce detailed description incidence, size, and shape this fracture, may be helpful driving choice both approach fixation for...

10.1097/bot.0b013e31818f8dc1 article EN Journal of Orthopaedic Trauma 2008-12-19

While searching for derivatives of d-tubocura- rine, Barlow and Ing (1) Paton Zaimis (2) independently synthesized a series poly- methylene bistrimethylammonium salts.The lat- ter investigators demonstrated that the pharma- cological properties this were related to length polymethylene chain; deca- compound produced neuromuscular block while penta hexa-compounds prevented transmission impulses across synapses in all autonomic ganglia.They also carried out pre- liminary trials man (3) but...

10.1172/jci102857 article EN Journal of Clinical Investigation 1953-12-01

Objectives: This study is designed to test the comparative strength of lateral-only locked plating medial and lateral nonlocked in a cadaveric model bicondylar proximal tibial plateau fracture. Methods: Ten matched pairs human tibia specimens were used for biomechanical testing. Cyclic loading using materials testing device simulated initial range motion load bearing following surgical repair. Subsidence condyles was measured 10,000 cycles from 100N 1,000N; maximum failure on condyle both...

10.1097/bot.0b013e3180500359 article EN Journal of Orthopaedic Trauma 2007-05-01

Objective: The objective of this study is to establish the relative strength fixation a locking distal femoral plate compared with condylar blade plate. Methods: Eight matched pairs fresh-frozen cadaveric femurs were selected and evaluated for bone density. A gap osteotomy model was used simulate an OTA/AO A3 comminuted femur fracture. One each pair fixed plate; other, After 100 N preload 10,000 cycles between 1000 N, total displacement specimen assessed. completion cyclic loading, maximum...

10.1097/bot.0b013e31802bb372 article EN Journal of Orthopaedic Trauma 2007-01-01

The prudent use of prescription opiates is a central aspect current postsurgical pain management, but surgeons have no guidelines on appropriate duration opiate treatment. Furthermore, there are established data the effect physician counseling postoperatively.Retrospective surgeon-controlled cohort study.Level I regional academic trauma center.All Utah residents admitted to orthopaedic service with isolated operative musculoskeletal injury.One group patients was instructed at time index...

10.1097/bot.0000000000000085 article EN Journal of Orthopaedic Trauma 2014-03-25

The purpose of this study was to characterize demographics, healing time, and complications a large series operatively treated atypical femur fractures.Retrospective multicenter review.Seventeen academic medical centers.Bisphosphonate-related fractures as defined by American Society Bone Mineral Research. Fractures had be followed for at least 6 months or union revision.Operative treatment bisphosphonate-related fracture.Union time treatment, well information about the contralateral...

10.1097/bot.0000000000000516 article EN Journal of Orthopaedic Trauma 2015-12-25

Hypotensive doses of hexamethonium were administered intravenously to 19 patients with various types heart disease in congestive failure. Clinical improvement as judged by the usual methods was seen most cases. Intracardiac or pulmonary artery pressures paralleled fall arterial following four hypertensive It is suggested that hexamethonium, reducing total peripheral resistance and a redistribution blood volume, may interrupt vicious cycle

10.1161/01.cir.7.2.169 article EN Circulation 1953-02-01

Objectives Fracture is a common injury after traumatic event. The efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) to treat acute pain related fractures not well established. Methods Clinically relevant questions were determined regarding NSAID use in the setting trauma-induced with clearly defined patient populations, interventions, comparisons appropriately selected outcomes (PICO). These centered around (pain control, reduction opioid use) (non-union, kidney injury)....

10.1136/tsaco-2022-001056 article EN cc-by-nc Trauma Surgery & Acute Care Open 2023-02-01

The current mainstay of orthopaedic pain control is opioid analgesics but there are few studies in the literature evaluating effects opioids on bone healing.The purpose this study was to use a rat fracture model evaluate administration osseous union acute (4 weeks) and subacute (8 setting an operatively stabilized fracture. We asked following question: does morphine alter (1) callus strength; (2) volume formation; (3) morphology early remodeling final union?A 0.4-mm femoral osteotomy gap...

10.1007/s11999-013-3232-z article EN Clinical Orthopaedics and Related Research 2013-08-16

The aim of this study was to report the incidence arthrofibrosis knee and identify risk factors for its development following a fracture tibial plateau. We carried out retrospective review 186 patients (114 male, 72 female) with plateau who underwent open reduction internal fixation. Their mean age 46.4 years (19 83) follow-up was16.0 months (6 80). A total 27 (14.5%) developed requiring further intervention. Using multivariate regression analysis, use provisional external fixator (odds...

10.1302/0301-620x.97b1.34195 article EN The Bone & Joint Journal 2015-01-01

To better characterize operative agreement and disagreement among orthopaedic surgeons treating lateral compression type 1 (LC-1) pelvic fractures in an effort to improve communication between care providers patient care.Decision analysis.Level trauma center.Twenty-seven LC-1 cases were selected represent a wide array of injuries. Each case was presented with 3 plain radiographs (anteroposterior, inlet, outlet) scrollable computed tomography at the OTA national meeting. Attendees queried...

10.1097/bot.0000000000000133 article EN Journal of Orthopaedic Trauma 2014-05-01

Objective: To compare the heat generation and pressure of a prototype irrigating aspirating intramedullary reaming system to traditional stepwise reaming. Design: This in vitro study used 8 pairs fresh-frozen human cadaver tibias. Thermocouples were mounted mid-diaphysis distal diaphysis. A transducer was placed distally assess pressure, load cell measured axial applied by surgeon, entire construct 37°C saline bath. One specimen from each pair underwent single-pass with reamer irrigator...

10.1097/bot.0b013e318038d952 article EN Journal of Orthopaedic Trauma 2007-03-01

The objective of the present study was to evaluate human synovial fluid for inflammatory cytokine concentrations following acute tibial plateau fracture. Our hypothesis that there would be an elevated response intra-articular fracture, and greater after high-energy compared with low-energy injuries.Between December 2011 June 2013, we prospectively enrolled forty-five patients Synovial aspirations were performed on injured uninjured knees. Twenty who required external fixator followed by...

10.2106/jbjs.n.00200 article EN Journal of Bone and Joint Surgery 2015-03-18
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