- Wound Healing and Treatments
- 3D Printing in Biomedical Research
- Graphene and Nanomaterials Applications
- Advancements in Transdermal Drug Delivery
- Pluripotent Stem Cells Research
- Nanoplatforms for cancer theranostics
- Advanced Sensor and Energy Harvesting Materials
- Cellular Mechanics and Interactions
- Electrospun Nanofibers in Biomedical Applications
- Advanced Drug Delivery Systems
- Enzyme Catalysis and Immobilization
- Biofuel production and bioconversion
- Carbon and Quantum Dots Applications
- Optical Coherence Tomography Applications
- Carbon Nanotubes in Composites
- Biocrusts and Microbial Ecology
- Luminescence Properties of Advanced Materials
- Optical Imaging and Spectroscopy Techniques
- Plant Growth Enhancement Techniques
- Lichen and fungal ecology
- Nerve injury and regeneration
- Silk-based biomaterials and applications
- Ocular Surface and Contact Lens
- Photodynamic Therapy Research Studies
- Hair Growth and Disorders
Pusan National University
2021-2024
Wound healing is the dynamic tissue regeneration process replacing devitalized and missing layers. With development of photomedicine techniques in wound healing, safe noninvasive photobiomodulation therapy receiving attention. Effective management challenged, however, by limited control geometrical mismatches on injured skin surface. Here, adhesive hyaluronic acid-based gelatin nanofibrous membranes integrated with multiple light-emitting diode (LED) arrays are developed as a skin-attachable...
Abstract Cryotherapy leverages controlled freezing temperature interventions to engender a cascade of tumor‐suppressing effects. However, its bottleneck lies in the standalone ineffectiveness. A promising strategy is using nanoparticle therapeutics augment efficacy cryotherapy. Here, cold‐responsive nanoplatform composed upconversion nanoparticles coated with silica – chlorin e6 hyaluronic acid (UCNPs@SiO 2 ‐Ce6‐HA) designed. This employed integrate cryotherapy photodynamic therapy (PDT)...
Recent advances in three-dimensional (3D) bioprinting technologies have enabled the fabrication of sophisticated live 3D tissue analogs. Despite existing hydrogel-based bioinks, development advanced bioink materials that can accurately reproduce composition a native extracellular matrix and mimic intrinsic properties laden cells remains challenging. In this study, printed skin equivalents incorporating hair follicle structures epidermal/papillary dermal layers were fabricated using gelatin...
Abstract Although efficient light delivery is required for various biomedical applications, the high stiffness of traditional silica‐based optical fibers limits their in vivo usage. In this study, highly deformable and stretchable soft are prepared based on mechanically tough hydrogels a double network (DN) structure comprising covalently crosslinked acrylamide ionically alginate using microfluidic device. Owing to optimized chemical composition, core/cladding structure, mechanical...
Abstract Recent advances in inorganic nanomaterial-based theranostics enabled imaging-guided molecular targeting and drug delivery, various combinations of theranostic systems. The term “theranostics” is defined as diagnosis processed with therapy simultaneously a specific connection between diagnosis. nanomaterials, representatively carbon, metal, ceramic, semiconductor-based exhibit their unique characteristics to be used applications. However, the unveiled human biosafety nanomaterials...
Hyaluronate (HA) has been widely investigated for noninvasive topical drug delivery of chemical drugs and biopharmaceuticals. However, previous systems have facilitated mostly by conjugation with HA, which can cause reduced therapeutic efficacy safety issues in chemically modified drugs. Here, HA nanogels were synthesized crosslinking via “click” chemistry a model without modification. The model-drug-encapsulating could be uptaken to the skin melanoma cells vitro HA-mediated endocytosis. In...
Carbon nanotubes (CNTs) have been regarded as emerging materials in various applications. However, the range of biomedical applications is limited due to aggregation and potential toxicity powder-type CNTs. To overcome these issues, techniques assemble them into macroscopic structures, such one-dimensional fibers, two-dimensional films, three-dimensional aerogels, developed. Among them, carbon nanotube fiber (CNTF) a aggregate CNTs, which can be used solve problem individual Furthermore,...
Recently, several three-dimensional (3D) bioprinting techniques have emerged for the synthesis of 3D tissue analogs. Accordingly, many researchers focused on development novel bioinks that can mimic natural extracellular matrix with cytocompatibility and biofunctionality. Hyaluronic acid collagen are most abundant proteins in skin known to support cellular behaviors. Herein, we developed tyramine-conjugated hyaluronic (HA-Tyr/Col-Tyr) hydrogel bioinks, which photocrosslinkable presence...
Fulvic acids (FAs) have been commercially used in cosmetics and agronomy due to their unique biological activities, such as plant stimulation anti-inflammatory effects. However, the extraction sources of FAs, peat, are currently limited. Consequently, new methods using renewable resources need be developed, while reproducing functions. Here, ionic liquids (ILs) effectively extracted fulvic-like substances (FLSs) from wood sawdust. The overall molecular weight distributions FLSs were similar...