A5018579377- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Infection Control in Healthcare
- Immune Cell Function and Interaction
- Parasite Biology and Host Interactions
- Dental Research and COVID-19
- Global Maternal and Child Health
- SARS-CoV-2 and COVID-19 Research
- T-cell and B-cell Immunology
- COVID-19 diagnosis using AI
- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Parasitic Infections and Diagnostics
- SARS-CoV-2 detection and testing
- Antibiotic Use and Resistance
- Pediatric Hepatobiliary Diseases and Treatments
- vaccines and immunoinformatics approaches
- Hepatitis Viruses Studies and Epidemiology
- Amoebic Infections and Treatments
- Parasites and Host Interactions
- Toxin Mechanisms and Immunotoxins
Instituut voor Tropische Geneeskunde
2018-2023
Hospital for Tropical Diseases
2020
Bernhard Nocht Institute for Tropical Medicine
2013
University of Tübingen
2012
Surface molecules are of major importance for host-parasite interactions. During Entamoeba histolytica infections, these interactions predicted to be prime tissue invasion, induction colitis and liver abscess formation. To date, however, little is known about the involved in processes, with only 20 proteins or protein families found exposed on E. surface. We have therefore analyzed complete surface proteome histolytica. Using cell biotinylation mass spectrometry, 693 putative...
We conducted a systematic review of healthcare-associated outbreaks and cross-sectional surveys related to the contamination antiseptics, disinfectants, hand hygiene products in healthcare settings low- middle-income countries (PROSPERO CRD42021266271). Risk bias was assessed by selected items ORION MICRO checklists. From 1977 onwards, 13 25 were found: 20 from Asia Africa. Products most associated with water-based chlorhexidine, chlorhexidine-quaternary ammonium compound combinations...
Abstract Background Kinesin-related gene diversity among strains and species of Leishmania may impact the sensitivity specificity serodiagnostic tests for visceral leishmaniasis (VL). Methods In this study, we report on recombinant expression novel Iranian infantum (MCAN14/47) homologue rK39 ( Li -rK39), in L. tarentolae . The diagnostic potential Li- antigen was evaluated an ELISA, using sera from 100 VL patients, 190 healthy endemic controls, 46 non-endemic controls 47 patients with other...
The selection pressure imposed by the parasite has a functional consequence on immune genes, leading to altered function in which regulatory T cells (Tregs) induced parasites during infectious challenges modulate or thwart effector cell mechanism.We identified and investigated polymorphisms gene IL2 its receptor IL2R alpha (also known as CD25) Gabonese individuals exposed plentiful parasitic infections.We two reported variants each for loci. Also were novel variants, -83 /-84 CT deletions...
To evaluate the diagnostic performance of five alternative serodiagnostic tests, serum samples from 100 confirmed visceral leishmaniasis (VL) patients, 197 healthy endemic individuals, and 58 non-VL patients living in southern Iran were compared. The VL defined as individuals with a positive result immunofluorescent antibody test (IFAT), having clinical signs symptoms appropriate response to treatment. index tests two direct agglutination DAT-ITM (Institute Tropical Medicine, Antwerp,...
The direct agglutination test (DAT) for visceral leishmaniasis (VL) is the serodiagnostic VL that has most robust sensitivity and specificity in field across all endemic regions. It based on trypsin-treated formaldehyde-fixed whole promastigote cells from Leishmania donovani. exact identity nature of epitopes DAT antigen cause with patients’ sera are currently unknown. In this study, we performed antigen-inhibition studies which revealed lipophosphoglycan (LPG) share epitopes. Antibody...