Lorenzo Isolan

ORCID: 0000-0003-2320-5925
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About
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Research Areas
  • Radiation Therapy and Dosimetry
  • Nuclear Physics and Applications
  • Advanced Radiotherapy Techniques
  • Nuclear reactor physics and engineering
  • Nuclear Materials and Properties
  • Laser-Plasma Interactions and Diagnostics
  • Radiation Detection and Scintillator Technologies
  • Radiation Dose and Imaging
  • Advanced X-ray and CT Imaging
  • Effects of Radiation Exposure
  • Fusion materials and technologies
  • Pulsed Power Technology Applications
  • Medical Imaging Techniques and Applications
  • Integrated Circuits and Semiconductor Failure Analysis
  • Space Science and Extraterrestrial Life
  • Management, Economics, and Public Policy
  • Planetary Science and Exploration
  • Magnetic confinement fusion research
  • Digital Radiography and Breast Imaging
  • Connexins and lens biology
  • Nuclear and radioactivity studies
  • Radiation Effects in Electronics
  • Medical Image Segmentation Techniques
  • Advanced MRI Techniques and Applications
  • Space exploration and regulation

University of Bologna
2016-2024

Istituto Nazionale di Fisica Nucleare
2022-2024

Istituto Nazionale di Fisica Nucleare, Sezione di Bologna
2022-2023

Centro Cardiologico Monzino
2018-2019

European Institute of Oncology
2018-2019

Radiation therapy is a useful and standard tumor treatment strategy. Despite recent advances in delivery of ionizing radiation, survival rates for some cancer patients are still low because recurrence radioresistance. This why many novel approaches have been explored to improve radiotherapy outcome. Some strategies focused on enhancement accuracy radiation the generation greater beams, example with higher dose rate. In present study we proposed an vitro research biological effects very high...

10.1371/journal.pone.0199312 article EN cc-by PLoS ONE 2018-06-29

Abstract The current framework of radiological protection occupational exposed medical workers reduced the eye-lens equivalent dose limit from 150 to 20 mSv per year requiring an accurate dosimetric evaluation and increase understanding radiation induced effects on Lens cells considering typical scenario operators. Indeed, it is widely accepted that genomic damage epithelial (LEC) a key mechanism cataractogenesis. However, relationship between apoptosis cataractogenesis still controversial....

10.1038/s41598-020-78383-2 article EN cc-by Scientific Reports 2020-12-10

One method for finding reliable and cost-effective solutions designing radioisotope production systems is represented by the "digital twin" philosophy of design. Looking at cyclotron solid targets, uncertainties particle beam, material composition geometry play a crucial role in determining results. The difference between what has been designed can be effectively manufactured, where processes such as electroplating are poorly controllable generate large non-uniformities deposition, must also...

10.1038/s41598-022-23048-5 article EN cc-by Scientific Reports 2022-11-12

10.1016/j.radphyschem.2024.111786 article EN Radiation Physics and Chemistry 2024-04-25

FENDL nuclear data libraries are planned to be adjourned soon with a new release (v3.2). A beta version, together previous releases and the ENDF/B-VIII.0, have been tested on sphere leakage ITER 1D computational benchmarks using JADE, under development verification validation (V&V) tool. The consistency checks performed v3.2 did not spot any formal inconsistency comparison of results show that, in general, FENDLv3.2 behaviour is quite similar v3.1d one. Nevertheless, few significant...

10.1088/1741-4326/ac121a article EN Nuclear Fusion 2021-07-08

The use of Monte Carlo methods for the set up Treatment Planning Systems (TPS) in radiotherapy applications is a current standard. most advanced modeling techniques aim at directly link output CT scans to patient-specific model build instead standard phantoms and look-up tables. This represents critical step since even accurate segmentation organ volume definition must be translated into suitable input code. During that step, segmented usually mapped on regular geometrical lattice (voxels)....

10.1080/10420150.2019.1596104 article EN Radiation effects and defects in solids 2019-03-29

Several kinds of isotopes are generated during radiotherapy treatments with high-energy electron sources due to the onset many nuclear reactions. These often unstable, can appear both in device and treatment chamber materials and, as a consequence decay process, involving also gamma-ray emissions, some additional dose is given patient unit staff. effects have been experimentally monitored LaBr detector for gamma spectrometry. Then measurement setup data benchmarked through Monte Carlo (MC)...

10.1080/10420150.2016.1266358 article EN Radiation effects and defects in solids 2016-09-01

The Directive 2013/59/Euratom established a reduction of the occupational exposure limits to lens. Since it is become crucial estimate lens absorbed dose, individual variability exposed worker's ocular conformations with respect data estimated their personal dosimetry has been studied. anterior eye conformation 45 workers was acquired Scheimpflug imaging and classified according vision conditions (emmetropia, myopia or hypermetropia). Three models were computed, two reconstructions,...

10.1088/1361-6498/abf56f article EN Journal of Radiological Protection 2021-04-07
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