A5038886349- Reconstructive Facial Surgery Techniques
- Facial Nerve Paralysis Treatment and Research
- Organ and Tissue Transplantation Research
- Tissue Engineering and Regenerative Medicine
- Hippo pathway signaling and YAP/TAZ
- Electrospun Nanofibers in Biomedical Applications
- Cutaneous Melanoma Detection and Management
- Flavonoids in Medical Research
- Oral microbiology and periodontitis research
- Connective tissue disorders research
- S100 Proteins and Annexins
- Head and Neck Surgical Oncology
- Protease and Inhibitor Mechanisms
- Cancer Cells and Metastasis
- Skin and Cellular Biology Research
- Cleft Lip and Palate Research
- dental development and anomalies
- Bioactive natural compounds
- Hair Growth and Disorders
- Wound Healing and Treatments
- Phytochemistry and biological activity of medicinal plants
- Biological and pharmacological studies of plants
- Biomedical Ethics and Regulation
- Connexins and lens biology
- Fibroblast Growth Factor Research
Henan Provincial People's Hospital
2014-2024
Zhengzhou University
2018-2024
Henan University
2019
Total Rehab
2017
The diabetic foot ulcer (DFU) may be associated with late healing and septic manifestation, subsequently lead to amputation which is an overpriced incident. Neferine alkaloid found lotus. possesses many physiological functions such as anti-inflammatory, antioxidant, antimicrobial activity anticancer effect. aim of the present study was evaluate effect topical application based on neferine, in streptozotocin-induced incision wound models rats. data demonstrated activities via macroscopic,...
Abstract Background Overexpression of fibroblast growth factor receptor 3 (FGFR3) has been linked to tumor progression in many types cancer. The role FGFR3 melanoma remains unclear. In this study, we aimed uncover the and metastasis melanoma. Methods knockdown overexpression strategies were employed investigate effects on colony formation, cell apoptosis, proliferation, migration, vitro invasion, along with a xenografts mouse model. protein expression levels extracellular signal-regulated...
The management of burn injuries presents a significant challenge in clinical settings, yet an optimal solution remains elusive. Therefore, this study aimed to develop topical therapeutic formulation address the complex issues hindering wound healing. Emphasizing sustained presence bioactive principles, we synthesized gel derived from decellularized caprine small intestine submucosa (D-CIS) and encapsulated it with nano-formulations cerium oxide curcumin create dressing material enhanced...
The aim of our study was to use tissue expansion for the treatment giant congenital melanocytic nevi upper extremity and examine potential advantages over traditional techniques. There were 3 stages in extremities using expansion: first, expander inserted into subcutaneous pocket; second, removed, lesions excised, wound placed pocket delay healing; third, residual lesion excised pedicle removed. flap then unfolded resurface wound. During period between June 2007 December 2015, there 11...
Aim To make a gene diagnosis for family with Ectodysplasin A ( EDA ) mutation as well prenatal diagnosis, and report novel mutation. Methods All coding sequences flanking of were analyzed by Sanger sequencing in the proband, then, according to was performed on members. Based results above, pathogenic finally identified, which used making diagnosis. Results revealed c.302_303del CC [p.Pro101HisfsX11] proband. This induced frame shift led early termination translation because there codon TAA...
To carry out genetic testing and prenatal diagnosis for a family affected with recessive dystrophic epidermolysis bullosa (RDEB).All exons of the COL7A1 gene their flanking regions were subjected to PCR Sanger sequencing. Suspected variant was validated in members, based on which provided.Sanger sequencing found that proband has carried two variants gene, namely c.7289delC (p.Pro2430Glnfs*36) c.7474C>T (p.Arg2492*), respectively derived from his mother father. The same not among 100 healthy...
Objective To investigate the biological changes after transplantation of expanded skin and discuss mechanism retraction for further improving clinical efficacy.Methods Eight adult dogs were used.On back each animal,4 rectangular expanders implanted beneath panniculus carnosus bilaterally.Final injection was terminated through weekly over an 8-week period.Dogs divided into 4 groups (n =2 each).At 3rd week,6th week,3rd month 6th inset flaps respectively,the skin-flap area measured with...
To investigate the association between polymorphisms of 5'-UTR -52G/A (rs1799946), -44C/G (rs1800972), -20G/A (rs11362) in DEFB1 gene with chronic periodontitis Henan Han population.Peripheral blood genomic DNA 436 patients and 440 healthy controls were extracted subjected to PCR-Sanger sequencing determine genotypes (rs1800972) (rs11362). The distribution genotypes, allele frequencies risk factors analyzed by chi-square test Logistic regression.There was no significant difference genotype...