Sotirios Roussos

ORCID: 0000-0003-2347-0817
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About
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Research Areas
  • HIV, Drug Use, Sexual Risk
  • HIV/AIDS Research and Interventions
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 epidemiological studies
  • COVID-19 Clinical Research Studies
  • HIV Research and Treatment
  • Hepatitis C virus research
  • COVID-19 Pandemic Impacts
  • Homelessness and Social Issues
  • Sex work and related issues
  • Animal Virus Infections Studies
  • Vaccine Coverage and Hesitancy
  • COVID-19 and Mental Health
  • COVID-19 Digital Contact Tracing
  • Hepatitis B Virus Studies
  • Influenza Virus Research Studies
  • Opioid Use Disorder Treatment
  • HIV/AIDS drug development and treatment
  • Medication Adherence and Compliance
  • Nonmelanoma Skin Cancer Studies
  • Cancer and Skin Lesions
  • Census and Population Estimation
  • Williams Syndrome Research
  • Misinformation and Its Impacts
  • Antibiotic Resistance in Bacteria

National and Kapodistrian University of Athens
2019-2025

Senologic Hellenic Society
2021-2022

European University Cyprus
2021

National Public Health Organization
2021

San Diego State University
2004

Introduction Greece is a country with limited spread of SARS-CoV-2 and cumulative infection attack rate 0.12% (95% CI 0.06–0.26). Health care workers (HCWs) are well-recognized risk group for COVID-19. The study aimed to estimate the seroprevalence antibodies in nosocomial setting assess potential factors. Methods HCWs from two hospitals participated study. Hospital-1 was tertiary university affiliated center, involved COVID-19 patients while hospital-2 specialized cardiac surgery center not...

10.1371/journal.pone.0243025 article EN cc-by PLoS ONE 2020-12-03

Greece imposed a nationwide lockdown in March 2020 to mitigate transmission of severe acute respiratory syndrome coronavirus 2 during the first epidemic wave. We conducted survey on age-specific social contact patterns assess effects physical distancing measures and used susceptible-exposed-infectious-recovered model simulate epidemic. Because multiple were implemented simultaneously, we assessed their overall contribution each measure. Before implemented, estimated basic reproduction number...

10.3201/eid2702.203412 article EN cc-by Emerging infectious diseases 2021-01-19

Vaccine hesitancy is a major barrier to achieving large-scale COVID-19 vaccination. We report trends in vaccination intention and associated determinants from surveys the adult general population Greece. Four cross-sectional phone were conducted November 2020 February, April May 2021 on nationally representative samples of adults Multinomial logistic regression was used combined data evaluate independent predictors unwillingness/uncertainty. Vaccination increased 67.6% 84.8% 2021....

10.3390/vaccines10030470 article EN cc-by Vaccines 2022-03-18

Several lines of evidence suggest that binding SARS-CoV-2 antibodies such as anti-SARS-CoV-2 RBD IgG (anti-RBD) and neutralising (NA) are correlates protection against SARS-CoV-2, the correlation anti-RBD NA is very high. The effectiveness (VE) BNT162b2 in preventing infection wanes over time, this reduction mainly associated with waning immunity, suggesting kinetics might be interest to predict VE. In a study 97 health care workers (HCWs) vaccinated vaccine, we assessed 30-250 days after...

10.3390/vaccines10020285 article EN cc-by Vaccines 2022-02-13

Understanding the factors that affect transmissibility of SARS-CoV-2 remains important to keep transmission low and maximize health benefits vaccination. We assessed associated with based on contact tracing data.From 1 October 9 December 2020, 29,385 laboratory-confirmed cases (index cases, i.e. first identified or earliest symptom onset in a setting) 64,608 traced contacts were Greece. prevalence symptoms calculated secondary attack rates infectivity susceptibility infection.There 11,232...

10.1080/23744235.2021.1995627 article EN Infectious Diseases 2021-11-07

Due to their higher risk of developing life-threatening COVID-19 disease, solid organ transplant (SOT) recipients have been prioritized in the vaccination programs many countries. However, there is increasing evidence reduced immunogenicity SARS-CοV-2 vaccination. The present study investigated humoral response, safety, and effectiveness after two mRNA vaccines 455 SOT recipients. Overall, antibody response rate was low, at 39.6%. Higher detected among individuals vaccinated with mRNA1273...

10.3390/vaccines10020190 article EN cc-by Vaccines 2022-01-25

Background Late HIV diagnosis (CD4 + T-cell count < 350 cells/μL, or with an AIDS-defining event) remains a persistent challenge in Greece, indicating potential missed opportunities (MOs) for earlier testing. Aim To determine the frequency of indicator conditions (ICs) preceding and to quantify MOs testing at nationwide level Greece. Methods This multicentre retrospective study analysed data on 823 antiretroviral therapy-naive adults (≥ 18 years) diagnosed during 2019–21. Medical records...

10.2807/1560-7917.es.2024.29.48.2400138 article EN cc-by Eurosurveillance 2024-11-28

Abstract Greece is a country with limited spread of SARS-CoV-2 and cumulative infection attack rate 0.12% (95%CI 0.06%-0.26%). Health care workers (HCWs) are well-recognized risk group for COVID-19. The study aimed to estimate the seroprevalence antibodies in two hospitals assess potential factors. Hospital-1 was involved COVID-19 patients while hospital-2 not. A validated, rapid, IgM/IgG antibody point-of test used. 1,495 individuals consented participate (response 77%). anti-SARS-CoV-2...

10.1101/2020.06.23.20137620 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2020-06-23

BNT162b2 has proven to be highly effective, but there is a paucity of data regarding immunogenicity factors and comparison between response vaccination natural infection. This study included 871 vaccinated healthcare workers (HCW) 181 patients with Immunogenicity was assessed by measuring anti-SARS-CoV-2 against the RBD domain spike protein (anti-RBD). Samples were collected 1-2 weeks after or 15-59 days post-onset symptoms. Post-vaccine anti-RBD concentrations associated age, gender,...

10.3390/vaccines9091017 article EN cc-by Vaccines 2021-09-13

Abstract Background and Aims The human immunodeficiency virus (HIV) outbreak among people who inject drugs (PWID) in Athens, Greece 2011–13 was the largest recent epidemic Europe North America. We aimed to assess trends HIV prevalence, drug use access prevention PWID Athens estimate incidence identify risk factors explore HIV‐1 dispersal using molecular methods during 2014–20. Methods Two community‐based HIV/hepatitis C programmes on were implemented 2012–13 ( n = 3320) 2018–20 1635) through...

10.1111/add.15812 article EN Addiction 2022-01-24

Abstract In Greece, a nationwide lockdown to mitigate the transmission of SARS-CoV-2 was imposed on March 23, 2020. As by end April first epidemic wave is waning, it important assess infection attack rate and quantify impact physical distancing. We implemented survey social mixing patterns before during lockdown. estimated R 0 from surveillance data assessed its decline as result distancing based contacts data. applied Susceptible-Exposed-Infectious-Recovered model estimate fatality ratio...

10.1101/2020.05.27.20114017 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-05-28

Abstract Background Telehealth holds the potential to expand healthcare access for people who use drugs (PWUD). However, approaches increase PWUDs’ digital are not well-understood. We studied accessibility among PWUD. Methods employed respondent-driven sampling recruit 162 PWUD in Athens, Greece collect data via a structured questionnaire. Participants were aged at least 18 years and had an injection drug (IDU) history. assessed current internet computer access, experience with telemedicine....

10.1101/2024.08.19.24312251 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-08-20

Carbapenemase-producing Enterobacterales (CPE) comprise important nosocomial pathogens worldwide. Colonized patients are the source of further dissemination in healthcare settings. Considering that timely detection CPE carriers is pivotal but universal screening unfeasible, we aimed to develop and validate a prediction score detect harbouring on hospital admission.The study was conducted tertiary care located endemic area. Rectal swabs were obtained from 2303 patients, screened shortly after...

10.1093/jac/dkac321 article EN Journal of Antimicrobial Chemotherapy 2022-09-02

BackgroundRASopathies account for nearly 20% of cases childhood hypertrophic cardiomyopathy (HCM). Sudden cardiac death (SCD) occurs in patients with RASopathy-associated HCM, but the risk factors SCD have not been systematically evaluated.AimTo validate HCM Risk-Kids prediction model children and investigate potential specific predictors this population.MethodsValidation was performed a retrospective cohort 169 from 15 international paediatric cardiology centres. Multiple imputation by...

10.1016/j.ijcard.2023.131405 article EN cc-by International Journal of Cardiology 2023-09-28

ABSTRACT Background and Aims The HIV outbreak among People Who Inject Drugs (PWID) in Athens, Greece 2011-2013 was the largest recent epidemic Europe North America. We aim to assess trends prevalence, drug use access prevention PWID estimate incidence identify risk factors explore HIV-1 dispersal using molecular methods during 2014-2020. Methods Two community-based HIV/hepatitis C programs on were implemented 2012-2013 (N=3,320) 2018-2020 (N=1,635) through consecutive Respondent-Driven...

10.1101/2021.06.24.21258830 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2021-06-25

<h3>Background:</h3> Rheumatoid arthritis (RA) is treated successfully with biologic disease-modifying anti-rheumatic drugs (bDMARDs). However, a significant withdrawal rate, due to non-responsiveness or toxicity, remains major barrier for their long-term use. <h3>Objectives:</h3> To determine the rate of first bDMARD in large cohort RA patients either, toxicity. <h3>Methods:</h3> In this study, were included retrospectively 220 from our outpatient clinic. The following bDMARDs evaluated:...

10.1136/annrheumdis-2019-eular.7308 article EN Annals of the Rheumatic Diseases 2019-06-01

Background and Objectives: Solid organ transplant (SOT) recipients have a higher risk of suffering from severe Coronavirus (COVID-19) compared to the general population. Studies shown impaired immunogenicity mRNA vaccines in this high-risk population; thus, SOT been prioritized globally for primary booster doses. Materials Methods: We analyzed 144 who had previously received two doses BNT162b2 or mRNA1273 vaccine, were subsequently vaccinated with dose vaccine. Humoral cellular immune...

10.3390/medicina59061075 article EN cc-by Medicina 2023-06-02
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