Sara Fascendini

ORCID: 0000-0003-2370-6295
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About
Contact & Profiles
Research Areas
  • Dementia and Cognitive Impairment Research
  • Geriatric Care and Nursing Homes
  • COVID-19 and Mental Health
  • Intensive Care Unit Cognitive Disorders
  • Healthcare professionals’ stress and burnout
  • Anesthesia and Neurotoxicity Research
  • Long-Term Effects of COVID-19
  • Anesthesia and Sedative Agents
  • Cognitive Functions and Memory
  • Aging, Elder Care, and Social Issues
  • Intergenerational Family Dynamics and Caregiving
  • Mindfulness and Compassion Interventions
  • Alzheimer's disease research and treatments
  • Schizophrenia research and treatment
  • Frailty in Older Adults
  • COVID-19 Clinical Research Studies
  • Opioid Use Disorder Treatment
  • Virtual Reality Applications and Impacts
  • Child and Adolescent Psychosocial and Emotional Development
  • Mental Health and Patient Involvement
  • Healthcare Systems and Practices
  • Death Anxiety and Social Exclusion
  • Palliative Care and End-of-Life Issues
  • Neurobiology of Language and Bilingualism
  • Pain Management and Opioid Use

Fondazione Europea Ricerca Biomedica
2016-2024

Azienda Ospedaliera San Gerardo
2022

University of Florence
2021

Aristotle University of Thessaloniki
2021

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2020

Informal care estimates for use in health-economic models are lacking. We aimed to estimate the association between informal time and dementia symptoms across Europe. A secondary analysis was performed on 13,529 observations 5,369 persons from 9 European pooled cohort or trial studies community-dwelling with dementia. mixed regression model fitted spent instrumental basic activities of daily living using disease severity demographic characteristics. Daily 0.5 hours higher moderate compared...

10.1016/j.tjpad.2024.100015 article EN cc-by The Journal of Prevention of Alzheimer s Disease 2025-01-01

Abstract Background Healthcare workers represent one of the most affected categories by adverse effects COVID-19 pandemic on mental health. Excessive stress and anxiety are critical factors that could compromise work performance. Besides, high levels may have long-term physical psychological consequences. Recent studies investigated virtual reality to reduce among healthcare during pandemic. However, proposed interventions important limitations related their location (i.e., research lab...

10.1186/s13063-022-06337-2 article EN cc-by Trials 2022-06-02

Abstract Background COVID-19 outbreak has led to severe health burden in the elderly. Age, morbidity and dementia have been associated with adverse outcome. Aims To evaluate impact of on status home-dwelling patients. Methods 848 outpatients contacted from April 27 30 evaluated by a semi-structured interview possible complication due February 21 30. sex, education, clinical characteristics (including diagnosis dementia) flu vaccination history were obtained previous medical records. Items...

10.1007/s40520-020-01676-z article EN cc-by Aging Clinical and Experimental Research 2020-09-12

Virtual reality can help individuals to manage stress and anxiety. In addition its efficacy in reducing anxiety through relaxation, virtual be helpful for psychoeducation. However, date, few studies have explored this topic. Therefore, mixed-methods sequential explanatory study, aimed investigate the usability, sense of presence, emotional response, effect on learning MIND-VR, a psychoeducational experience created offer information Twenty healthcare workers (60% female; mean age 43 ± 10)...

10.3390/app12189110 article EN cc-by Applied Sciences 2022-09-10

This pilot study evaluated the efficacy and safety of prolonged-release oxycodone/naloxone (OXN-PR) in older subjects with chronic pain mild-to-moderate cognitive impairment.This was a prospective, observational, open-label 45-day duration. Patients moderate-to-severe naïve to strong opioids were recruited from nursing homes Alzheimer's disease centers. OXN-PR initiated at low doses (5 mg od or bid) increased maximum 20 bid. The primary endpoint intensity reduction ≥30% baseline (T0) 15 days...

10.2147/ndt.s98511 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2016-03-01

Background: Nursing home placement (NHP) can be the final step of patients with Alzheimer’s disease. Objective: We aimed to identify NHP predictors among 508 people dementia a 3-year follow-up. Methods: analyzed data from international observational RECage study, involving especially disease and comparing cohort enrolled by five centers Special Care Unit for BPSD (behavioral psychological symptoms dementia) another one six lacking this facility. The tertiary objective study was assess...

10.3233/jad-230878 article EN Journal of Alzheimer s Disease 2024-03-12

Background: Behavioral and psychological symptoms of dementia (BPSD) are quite challenging problems during the course. Special Care Units for people with (PwD) BPSD (SCU-B) residential medical structures, where patients temporarily admitted, in case unmanageable behavioral disturbances at home. Objective: RECage (REspectful Caring AGitated Elderly) aspires to assess short long-term effectiveness SCU-Bs toward alleviating improving quality life (QoL) PwD their caregivers. Methods: is a...

10.3233/jad-201215 article EN other-oa Journal of Alzheimer s Disease 2021-03-12

Background: Behavioral and psychological symptoms of dementia (BPSD) bring complexity in the clinical management people with dementia; therefore, it is important to evaluate different models care, such as Special Care Units (SCU-B).∥ Objective: To SCU-B effectiveness toward alleviating BPSD improving quality life (QoL) patients their caregivers.∥ Methods: ReCAGE was a multicenter, controlled, longitudinal study where 508 were enrolled two cohorts: 262 from centers endowed SCU-B, 246 without...

10.3233/jad-230708 article EN Journal of Alzheimer s Disease 2023-11-01

Background: Dementia is a priority for global public health. The management of behavioral and psychological symptoms dementia (BPSD) one the highest ongoing challenges needs new approaches. special care unit people with BPSD (SCU-B) viewed in this context as further medical intervention. Aim: study aims to explore SCU-B units order describe their main characteristics relation different implementation contexts, identify replicability, examine social innovation elements promoted by units....

10.3390/ijerph192416913 article EN International Journal of Environmental Research and Public Health 2022-12-16

Virtual reality (VR) is helpful for the management of stress and anxiety. However, current interventions have limitations related to location (ie, therapist's office or hospitals) content virtual experiences only relaxation). This randomized pilot trial aims investigate efficacy acceptability a brief remote VR-based training supporting anxiety in sample Italian health care workers. A total 29 doctors nurses (n=21; 72% female; mean age 35.6, SD 10.3 years) were recruited VR intervention group...

10.2196/50326 article EN cc-by JMIR Serious Games 2024-11-20

One of the most widely used instruments for assessing agitation in dementia patients is Cohen-Mansfield Agitation Inventory (CMAI), nevertheless no global score has been proposed. The aim this study is: (a) to conduct a confirmatory (CFA) and exploratory factor analysis (EFA) CMAI on people with Psychological Behavioral Symptoms (BPSD), (b) propose an alternative structure, based clinical criteria including all items.Confirmatory analyses were carried out 29 items administered at baseline...

10.3390/brainsci13071025 article EN cc-by Brain Sciences 2023-07-03

Abstract Despite international guidelines, cognitive behavioural therapy for early psychosis (CBTep) is still under-used in daily clinical practice, mainly due to the lack of specific skills among mental health professionals. The aim study was evaluate feasibility and efficacy a CBTep training course investigate impact trainees’ variables on level acquisition. An intensive graded programme consisting 112 hours plenary lectures, 30 group supervision 3 months practical offered professionals 65...

10.1017/s1754470x20000355 article EN cc-by The Cognitive Behaviour Therapist 2020-01-01

<sec> <title>BACKGROUND</title> Virtual reality (VR) is helpful for the management of stress and anxiety. However, current interventions have limitations related to location (ie, therapist’s office or hospitals) content virtual experiences only relaxation). </sec> <title>OBJECTIVE</title> This randomized pilot trial aims investigate efficacy acceptability a brief remote VR-based training supporting anxiety in sample Italian health care workers. <title>METHODS</title> A total 29 doctors...

10.2196/preprints.50326 preprint EN 2023-06-27

Abstract Background The RECage Project, funded by the European Commission, in framework of H2020 RIA projects, has a threefold objective: a) to validate clinical intervention (the Special Care Unit for Behavioural and Psychological Symptoms Dementia: acronym SCU‐B); b) adapt it produce consensus document on model SCU‐B c) promote implementation scaling up intervention. first objective is pursued through trial comparing two cohorts persons with dementia any etiology important BPSD, one...

10.1002/alz.040403 article EN Alzheimer s & Dementia 2020-12-01
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