A5031459746- Frailty in Older Adults
- Dementia and Cognitive Impairment Research
- Intensive Care Unit Cognitive Disorders
- Geriatric Care and Nursing Homes
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Disease Management Strategies
- Nutrition and Health in Aging
- Health disparities and outcomes
- Aging and Gerontology Research
- Atrial Fibrillation Management and Outcomes
- Cardiac Health and Mental Health
- Long-Term Effects of COVID-19
- Health and Well-being Studies
- Anesthesia and Sedative Agents
- Nutritional Studies and Diet
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Global Health Care Issues
- Heart Failure Treatment and Management
- COVID-19 Clinical Research Studies
- Palliative Care and End-of-Life Issues
- Epilepsy research and treatment
- Blood Pressure and Hypertension Studies
- Alzheimer's disease research and treatments
- Health and Wellbeing Research
Fondazione Poliambulanza Istituto Ospedaliero
2015-2024
Azienda Ospedaliera Universitaria Senese
2023
Policlinico S.Orsola-Malpighi
2023
Ospedale San Paolo
2023
IRCCS Ospedale San Raffaele
2023
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2023
Società Italiana di Cardiologia
2019-2022
Società Italiana di Fisica
2020
Université Paris-Sud
2020
Gruppo di Ricerca Geriatrica
2001-2012
The Mini‐Mental State Examination (MMSE), a brief test to assess cognitive status, is heavily influenced by age and education. It was administered 1019 elderly subjects (aged 65–89 years) living in three different Italian cities. A statistical non‐linear regression model built up order obtain adjustment coefficients reduce the influence of demographic variables on MMSE raw scores. Age educational level were significantly independently associated with score. Results multiple linear...
To determine the association between quality of life measures and sensory impairment in aged individuals living at home.SurveyA community survey, carried out historical center a town Northern Italy.1191 non-institutionalized elders (age 70-75 years).Comprehensive QOL questionnaire, free-field voice testing, Snellen eye chart.Single impairments (either visual or auditory) were significantly independently associated with increased risk for depression (odds ratio: 2.3, 95% confidence interval:...
No studies analyzing the role of dementia as a risk factor for mortality in patients affected by COVID-19. We assessed prevalence, clinical presentation and outcomes among subjects hospitalized COVID19 infection.
To date, delirium prevalence in adult acute hospital populations has been estimated generally from pooled findings of single-center studies and/or among specific patient populations. Furthermore, the number participants these not exceeded a few hundred. overcome limitations, we have determined, multicenter study, over single day large population patients admitted to and rehabilitation wards Italy. This is point study (called "Delirium Day") including 1867 older (aged 65 years or more) across...
Background: the debate about measures of chronic comorbidity in elderly is mainly due to lack consensus on pathogenetic models.
<h3>Importance</h3> Cerebral amyloidosis is a key abnormality in Alzheimer disease (AD) and can be detected vivo with positron emission tomography (PET) ligands. Although amyloid PET has clearly demonstrated analytical validity, its clinical utility debated. <h3>Objective</h3> To evaluate the incremental diagnostic value of florbetapir F 18 addition to routine assessment patients evaluated for cognitive impairment. <h3>Design, Setting, Participants</h3> The Incremental Diagnostic Value...
Objectives Several physiological abnormalities that develop during COVID-19 are associated with increased mortality. In the present study, we aimed to a clinical risk score predict in-hospital mortality in patients, based on set of variables available soon after hospitalisation triage. Setting Retrospective cohort study 516 patients consecutively admitted for two Italian tertiary hospitals located Northern and Central Italy were collected from 22 February 2020 (date first admission) 10 April...
Objective. This hospital-based prospective study tests the hypothesis that, in a large group of hospitalized elderly patients, those who report functional decline between pre-illness baseline and hospital admission have higher risk death.
Objective : To compare the ability of Basic Activities Daily Living (BADL), Instrumental (IADL), and Physical Performance Test (PPT) to detect health status impairments. Patients Five hundred forty nine community‐dwelling elders (89.8% eligible elderly population) aged 70 over; mean age [was] 76.8 ± 6.1; 179 were males 370 females. Setting City Ospitaletto, Brescia, Northern Italy. Measurements A multidimensional questionnaire assessing demographic variables, indicators social activities,...
The nutritional intake of a large population noninstitutionalized older people living in an urban area was studied relation to socioeconomic conditions (living environment, income, and education) health status (affective, functional, physical health) identify the subgroups at risk for malnutrition. Twenty‐four‐hour dietary recall used determine percentage subjects with specific nutrients below two thirds 1980 Recommended Dietary Allowances. Ninety percent examined showed inadequate thiamine...
Abstract Introduction Anxiety disorders are less well studied in elderly people than other such as depression. In particular the diagnosis of anxiety is more difficult patients with Mild Cognitive Impairment (MCI) since current definition MCI does not mention neuropsychiatric symptoms. Objectives To validate Italian version Geriatric Inventory (GAI), an instrument that measures dimensional people, and assess whether subjects symptoms show different neuropsychological profiles comparison...
Delirium is a common geriatric syndrome. Few studies have been conducted in nursing home (NH) residents. The aim of this project was to perform point prevalence study delirium Italian NHs.Data collected 71 NHs are presented. Inclusion criteria were age ≥65 years and native speaker. Exclusion coma, aphasia, end-of-life status. Sociodemographic medical data recorded. assessed using the Assessment Test for Cognitive Impairment (4-AT). Patients with 4-AT score ≥4 considered delirium. Motor...
The aims of this study are to report the prevalence delirium on admission unit in patients hospitalized with SARS-CoV-2 infection, identify factors associated delirium, and evaluate association between in-hospital mortality.
The SARS-CoV-2 pandemic has led to a dramatic crisis of Health Care Systems worldwide, and older people have been among the most disadvantaged. Specific recommendations reports released both at International National level, regarding diagnosis management COVID-19 in elderly. However, little proposed for an appropriate response older, frail multimorbid patients different settings care (acute units, long term facilities, nursing homes primary care) geriatric syndromes (i.e. delirium,...
Abstract A questionnaire to assess quality of life in the elderly was developed under auspices European office World Health Organization. Stages construction instrument, which designed for international application, particularly at primary level, are described. The latest version is composed 49 self-assessment items, 31 can be grouped into 7 subscales: Physical Function, Self-Care, Depression and Anxiety, Cognitive Functioning, Sexual Life Satisfaction. remaining 18 items serve as moderators...
An eight-week double-blind, multicentre study was performed to evaluate the efficacy and safety of sertraline vs. fluoxetine in treatment major depression (DSM-III-R). There were 108 out-patients, from nine Italian centres, entered into study, whom 88 evaluable (48 sertraline, 40 fluoxetine). The final mean daily dose 72 mg for it 28 mg. Both groups showed a statistically significant improvement baseline at one week, this maintained until end all following measures: Hamilton Rating Scales...
Italian community norms for the Brief Symptom Inventory (BSI) in elderly are presented on 462 subjects. Means do not substantially differ from previously published US elderly. Higher scores were found women and subjects with social or distressing somatic conditions.
Clinicians have used measurements of pathological conditions and functional status to capture the heterogeneity older individuals for prognostic purposes. However, literature pays low attention physical changes.A retrospective cohort study investigate association between changes during hospitalization 3-month mortality. A total 1,119 acutely ill elderly patients admitted four beds arranged like a high-dependency area in geriatric unit (mean age 80.6 +/- 7.8 years) were subdivided into groups...
The study analyzes the characteristics of 54 nursing home patients (12 male, 42 female; mean age 81.9 +/- 7.9 years) with and without complaint fear falling, association this falling functional status. Patients who had a at baseline (n = 25) lower status (Barthel Index) score (69.8 22.3 vs. 79.3 15.4), scores for balance (8.4 4.4 10.6 3.7) gait (Tinetti; 6.7 3.3 8.3 2.6) were taking higher number psychotropic drugs (0.8 1.1 0.2 0.5) than those no 29). At 24 months' follow-up, 25 subjects...
Aim: to verify the capacity of basic and instrumental activities daily living (BADL IADL) disability scales a performance-based test (Physical Performance Test; PPT) detect effect on functional several common chronic conditions in elderly people. Method: cross-sectional survey entire population aged 70 over, Ospitaletto (Brescia, northern Italy)—549 subjects; 89.6% eligible population; 179 males 370 females—was carried out 1992. A multi-dimensional questionnaire administered at subject's...
To find a correlation between chronic nonrheumatic atrial fibrillation (CNRAF) and cognitive impairment in group of older, nondemented patients.Acute Care Unit for the Elderly, Poliambulanza Hospital, Brescia (Italy).Two hundred fifty-five hospital in-patients older than 70 years (42 with CNRAF 213 controls normal sinus rhythm) were assessed by complete clinical history, physical examination, ECG, serum albumin levels, APACHE II score, mental status (Mini-Mental State Exam [MMSE] Geriatric...