A5038569988- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Respiratory Support and Mechanisms
- Anesthesia and Neurotoxicity Research
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Cardiac Arrest and Resuscitation
- Airway Management and Intubation Techniques
- Pancreatitis Pathology and Treatment
- Family and Patient Care in Intensive Care Units
- COVID-19 Clinical Research Studies
- Healthcare Decision-Making and Restraints
- Gastrointestinal motility and disorders
- Patient Safety and Medication Errors
- Hemodynamic Monitoring and Therapy
- Esophageal and GI Pathology
- SARS-CoV-2 and COVID-19 Research
- Mechanical Circulatory Support Devices
- Pneumonia and Respiratory Infections
- Lung Cancer Diagnosis and Treatment
- Congenital Diaphragmatic Hernia Studies
- Pancreatic and Hepatic Oncology Research
- Ethics and bioethics in healthcare
Universidad Regional Autónoma de Los Andes
2024
Hospital Clínico de la Universidad de Chile
2014-2023
University of Chile
2011-2022
Beijing Tongren Hospital
2022
Capital Medical University
2022
Teradata (United States)
2012
Hospital Clínico de la Universidad Católica
2006
Positive end-expiratory pressure (PEEP) and prone positioning may induce lung recruitment affect alveolar dynamics in acute respiratory distress syndrome (ARDS). Whether there is interdependence between the effects of PEEP on these variables unknown.To determine high recruitment, cyclic recruitment/derecruitment, tidal hyperinflation how are influenced by recruitability.Mechanically ventilated patients (Vt 6 ml/kg ideal body weight) underwent whole-lung computed tomography (CT) during...
Since the publication of 2018 Clinical Guidelines about sedation, analgesia, delirium, mobilization, and sleep deprivation in critically ill patients, no evaluation adequacy assessment these recommendations were studied an international context. This survey aimed to investigate current practices if COVID-19 pandemic has changed them.This study was open multinational electronic directed physicians working adult intensive care units (ICUs), which performed two steps: before during pandemic.We...
Patients who develop postoperative delirium (POD) have several clinical complications, such as increased morbidity, hospital stays, higher costs, cognitive and functional impairment, mortality. POD is a condition preventable by standard non-pharmacological measures An intensive Occupational Therapy (OT) intervention has been shown to be highly effective in preventing critically ill medical patients, but it unknown the effect surgical patients. Thus, we designed prospective study with aim...
The authors describe two cases that developed organizing pneumonia (OP) associated with novel influenza A(H1N1) virus. These patients were admitted to intensive care unit (ICU) because of severe respiratory failure. After initial clinical improvement, both worsened their condition during second week ICU stay, presenting fever, increasing in inflammatory parameters and worsening oxygen exchange mechanics. Chest x-rays computed tomographies showed an increment on lung infiltrates, given by...
Deep sedation in critically ill patients is associated with a longer duration of mechanical ventilation and prolonged length stay the intensive care unit. Several protocols have been used to improve these outcomes. We implement evaluate an analgesia-based, goal-directed, nurse-driven protocol treat who receive ventilation.We performed prospective, two-phase (before-after), non-randomized multicenter study that involved 13 units Chile. After observational phase (observational group, n=155),...
Although patients with advanced or metastatic lung cancer have poor prognosis, admission to the ICU for management of life-threatening complications has increased over years. Patients newly diagnosed appear as good candidates admission, but more robust information assist decisions is lacking. The aim our study was evaluate prognosis unresectable patients.A retrospective multicentric analyzed outcome admitted a (diagnosis within month) between 2010 and 2013.Out 100 patients, 30 had small cell...
Small intestine bacterial overgrowth in patients with chronic pancreatitisBackground: Previous reports describe 30-40% of small (SIBO) pancreatitis (CP), SIBO is a cause persistent symptoms this group even when they are treated pancreatic enzymes.Aim: To asses the frequency CP.Patients and methods: We studied 14 CP using an hydrogen breath test lactulose to detect SIBO, nonabsorbable carbohydrate, whose results not influenced by presence exocrine insufficiency.Main signs were bloating 9...
The prognosis of severe COVID-19 patients has motivated research communities to uncover mechanisms SARS-CoV-2 pathogenesis also on a regional level. In this work, we aimed understand the immunological dynamics with different degrees illness, and upon long-term recovery. We analyzed immune cellular subsets SARS-CoV-2-specific antibody isotypes 66 admitted Hospital Clínico Universidad de Chile, which were categorized according WHO ten-point clinical progression score. These included 29...
non-pharmacological interventions to prevent delirium are useful in hospitalised older adults. However, they poorly implemented clinical practice. We aimed develop a software for bedside use by adults and improve their access these interventions.a transdisciplinary team composed of healthcare professionals, designers, engineers participated the development software. Scrum methodology was used coordinate work team, evaluated feasibility study.a touchscreen mobile devices that supports Android...
Prospective assessment of medication errors in critically ill patients a university hospital Background: Critically are especially vulnerable to (ME) due their severe clinical situation and the complexities management.Aim: To determine frequency characteristics ME identify shortcomings processes management an Intensive Care Unit.Patients Methods: During 3 months period, observational prospective randomized study was carried out ICU hospital.Every step patient's (prescription, transcription,...