- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Hemodynamic Monitoring and Therapy
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Sports Performance and Training
- Cardiac, Anesthesia and Surgical Outcomes
- Tracheal and airway disorders
- Airway Management and Intubation Techniques
- Congenital Diaphragmatic Hernia Studies
- Abdominal Surgery and Complications
- Sports injuries and prevention
- Traumatic Brain Injury and Neurovascular Disturbances
- Parathyroid Disorders and Treatments
- Patient Safety and Medication Errors
- Health and Lifestyle Studies
- Sports Analytics and Performance
- Muscle and Compartmental Disorders
- Appendicitis Diagnosis and Management
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pharmaceutical Practices and Patient Outcomes
- Mechanical Circulatory Support Devices
- Erythrocyte Function and Pathophysiology
- Organ Transplantation Techniques and Outcomes
Hospital Clínico de la Universidad de Chile
2013-2024
University of Chile
2008-2022
University of Glasgow
2021
Hebron University
2015
Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia
2015
Pontificia Universidad Católica de Chile
2002-2013
Centro Nacional de Medicina Tropical
2006-2008
Positive end-expiratory pressure (PEEP) and prone positioning may induce lung recruitment affect alveolar dynamics in acute respiratory distress syndrome (ARDS). Whether there is interdependence between the effects of PEEP on these variables unknown.To determine high recruitment, cyclic recruitment/derecruitment, tidal hyperinflation how are influenced by recruitability.Mechanically ventilated patients (Vt 6 ml/kg ideal body weight) underwent whole-lung computed tomography (CT) during...
The decision of when to stop septic shock resuscitation is a critical but yet relatively unexplored aspect care. This especially relevant since the risks over-resuscitation with fluid overload or inotropes have been highlighted in recent years. A guideline has proposed normalization central venous oxygen saturation and/or lactate as therapeutic end-points, assuming that these variables are equivalent interchangeable. However, physiological determinants both totally different, it legitimate...
Latin America bears an important burden of critical care disease, yet the information about it is scarce. Our objective was to describe structure, organization, processes care, and research activities in Latin-American ICUs.Web-based survey submitted ICU directors.ICUs located nine countries.Individual ICUs.None.Two hundred fifty-seven 498 (52%) surveys responded: 51% from Brazil, 17% Chile, 13% Argentina, 6% Ecuador, 5% Uruguay, 3% Colombia, between Mexico, Peru, Paraguay. Seventy-nine...
Endothelial damage and angiogenesis are fundamental elements of neovascularisation fibrosis observed in patients with coronavirus disease 2019 (COVID-19). Here, we aimed to evaluate whether early endothelial angiogenic biomarkers detection predicts mortality major cardiovascular events COVID-19 requiring respiratory support. Changes serum syndecan-1, thrombomodulin, factor concentrations were analysed during the first 24 h 10 days after hospitalisation high-flow nasal oxygen or mechanical...
Background: The procedures needed to insert nasojejunal tubes (NJTs) are often invasive or uncomfortable for the patient and require hospital resources. objectives of this study were describe our experience in inserting a self‐propelling NJT with distal pigtail end evaluate clinical validity cost efficacy enteral nutrition (EN) approach compared parenteral (PN). Materials Methods: Prospective from July 2009 December 2010, including hospitalized noncritical patients who required short‐term...
Intraabdominal hypertension (IAH) develops frequently in patients with septic shock. Even a moderate increase intraabdominal pressure (IAP) this setting could be associated high lactate levels. The authors conducted prospective, observational, nonrandomized control trial the surgical intensive care unit of an academic tertiary center. Twenty-seven shock (septic group), and 19 undergoing abdominal surgery more than two risk factors for IAH (postoperative group) were admitted consecutively to...