A5091121922- Pancreatitis Pathology and Treatment
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Helicobacter pylori-related gastroenterology studies
- Pancreatic and Hepatic Oncology Research
- Liver Disease Diagnosis and Treatment
- Inflammatory Bowel Disease
- Biomarkers in Disease Mechanisms
- Gastric Cancer Management and Outcomes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Health Promotion and Cardiovascular Prevention
- Paraoxonase enzyme and polymorphisms
- Lipid metabolism and disorders
- Bladder and Urothelial Cancer Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Economic and Financial Impacts of Cancer
- Healthcare Policy and Management
- S100 Proteins and Annexins
- Medical Malpractice and Liability Issues
- Telomeres, Telomerase, and Senescence
- Pathogenesis and Treatment of Hiccups
- Inflammation biomarkers and pathways
- Parkinson's Disease and Spinal Disorders
- Gout, Hyperuricemia, Uric Acid
Sağlık Bilimleri Üniversitesi
2021-2025
Istanbul University
2021-2023
University of Health Sciences Antigua
2023
University of Health Sciences
2023
State Hospital
2023
Haydarpaşa Numune Eğitim ve Araştırma Hastanesi
2021
Universidad CES
2021
Bakırköy Psychiatric Hospital
2020
Aims: We aimed to evaluate the presence of TERT promoter region mutations in transitional epithelial cell bladder cancer by analyzing h-TERT mutation high and low-grade tumors compare it with clinicopathological data patients. Methods: A total 90 patients diagnosed cancer, 60 30 high-grade were included this study. To detect gene DNA samples obtained, most frequently mutated was amplified PCR using forward reverse primers analysis performed sequence analysis. Results: positive 38 negative 22...
We read with great interest the research article titled “The Relationship of Gallstone Disease Serum RBP4 Level, Vitamin D, Lipid Profile, Insulin Resistance and Uric Acid Levels” by Kurt İnci et al., published in second issue Hitit Journal Science 2024 (1). would like to express our gratitude authors editorial team for their valuable contributions. Through this letter, we aim highlight specific elements that believe will enrich ongoing discussion around article.
Objective: This research aimed to evaluate whether the neutrophil lymphocyte and platelet (N/LP) ratio may be used predict risk of admission intensive care unit (ICU), need for mechanical ventilation in-hospital mortality in Coronavirus disease 2019 (COVID-19) cases. Methods: The study was conducted retrospectively on data 134 COVID-19 patients who were admitted ICU. N/LP calculated as follows: count x 100 / (lymphocyte count). Each member cohort categorised into 1 2 groups based their...
Background: To investigate the protective efficacy of pentoxifylline through biochemical parameters and histopathological scores in a caerulein- alcohol-induced experimental model chronic pancreatitis rats.Methods: A with caerulein alcohol was created female rats genus Sprague Dawley. Pentoxifylline administered doses 25 mg/kg (low dose) 50 (high as agent. Each group contained 8 animals. The groups were: 1 (control group); + alcohol, 2 (low-dose mg/kg, 3 (high-dose 4 (placebo); saline, 5...
Objectives We aimed to determine whether inflammatory indexes (II), including the neutrophil–lymphocyte ratio (NLR), C-reactive protein (CRP) albumin (CAR), CRP–lymphocyte (CLR), and systemic immune-inflammation index (SIII) can be diagnostic for common bile duct stones (CBDSs) excretion before endoscopic retrograde cholangiopancreatography (ERCP). Backgrounds Because of spontaneous clearance, it is mandatory ascertain presence CBDSs ERCP. Methods Retrospectively, we evaluated two groups....
The aim of the study was to evaluate whether a new and successful treatment opportunity can be provided in acute pancreatitis may prevent symptomatic treatments show its effect through etiopathogenesis. Therefore, we want investigate efficacy golimumab an experimental rat model cerulein-induced pancreatitis.A total 35 rats, including 7 rats each group, were distributed into 5 groups (sham, pancreatitis, placebo, pancreatitis+golimumab mg/kg, 10 mg/kg). An accomplished by intraperitoneal...
Background/aim: Acute pancreatitis is a clinical picture with wide range of symptoms from mild inflammation to multiorgan failure and death. The aim this study investigate the effects Adalimumab (ADA) on apoptosis in cerulein-induced acute model rats. Material methods: Experimental was created by applying 4 intraperitoneal cerulein injections at 1-h intervals. A total 40 rats, 8 each group, were randomly distributed into five groups. In groups that ADA treatment given, two different doses...
Introduction:The definitive diagnosis of coronavirus disease-2019 (COVID-19) infection is made by polymerase chain reaction (PCR) tests on nasopharyngeal and oropharyngeal swab samples.However, the presence viral RNA has also been identified in stool samples.In this study, we aimed to investigate relationship between severe acute respiratory syndrome-coronavirus-2 positivity outcomes COVID-19 disease.Methods: Fifty-four patients who were hospitalized April-June 2020 had positive PCR samples...
In ulcerative colitis (UC), serum vascular endothelial growth factor (sVEGF) concentrations are elevated and there conflicting results about calprotectin (SCP) sVEGF as biomarkers. We aimed to evaluate the relationship between SCP levels in UC patients associations of these molecules with phenotypes UC.
Background/aim: While chloride (Cl) is the most abundant anion in serum, it unfortunately one of commonly disregarded laboratory test results routinely drawn upon admission into medical intensive care unit (MICU). We aimed to investigate relation between in-hospital mortality, different pathologies requiring MICU, serum Cl levels, and other biochemical tests a tertiary center. Materials methods: The prospective study included data from 373 patients admitted ICU center 2017 2019. Data under...
Amaç: Ülseratif kolitte (ÜK) hastalık aktivitesinin değerlendirilmesi ve tedavinin şekillendirilmesi için birçok klinik aktivite indeksi non invaziv belirteç araştırılmış fakat hiçbiri inflamatuvar aktivitenin saptanmasında histopatolojik endoskopik incelemeler kadar kesin bulgu vermemiştir. Basit kolayca elde edilebilen nötrofillerin lenfosit plateletlere (N/LP) oranının ÜK’deki aktivitesi hastalığın şiddeti arasındaki ilişkiyi incelemeyi amaçladık.Gereç Yöntem: Baron skoru Klinik Kolit...
In this study, we aimed to assess the predictive value of Intermountain Risk Score (IMRS) in intensive care unit (ICU) patients with COVID-19.Our retrospective study included data 194 who were admitted COVID-19 ICU a tertiary center. diagnoses made by positive result from real-time reverse-transcriptase (RT) polymerase chain reaction (PCR) assay nasal and pharyngeal swab specimens. Patients had negative RT-PCR results or not under 18 years old excluded study. Complete blood count,...
Aims: There is evidence of anti-inflammatory qualities associated with a soluble receptor for advanced glycation end products (sRAGE). We aimed to evaluate whether serum sRAGE levels patients inflammatory bowel diseases (IBDs) could serve as biomarker by utilizing several clinical and laboratory models disease activity these individuals.
 Methods: This case-control study included 77 ulcerative colitis (UC) (51 males 26 females), 49 Crohn’s (CD) (33 16 females) 54 healthy controls (38...
Background.Short-and long-term lung damage after coronavirus disease 2019 (COVID-19) has been emphasized in many studies, but pulmonary-specific health-related quality of life (HRQOL) examined only a limited capacity.Objectives.In this study, we aimed to assess HRQOL and dyspnea among patients hospitalized for COVID-19 by applying the St George's Respiratory Questionnaire (SGRQ) patient groups 1, 3 6 months following discharge (groups T1, T3 T6). Materials methods.This cross-sectional study...
A 1-day point prevalence study was planned to obtain country data by determining the clinical characteristics, follow-up and treatment methods of coronavirus disease 2019 (COVID-19) cases that required intensive care unit (ICU) in second year pandemic.
Objective: Annexin A1(AnxA1) is an anti-inflammatory mediator. In the current study,we aimed to evaluate whether or not serum A1 levels of inflammatory boweldiseases (IBDs) patients relate clinical and laboratory traits IBDs.
 Methods: This case-control study included 67 ulcerative colitis (UC) (47 males 20 females), 53 Crohn’s disease (CD) (37 16 females) 60 healthy controls (36 24 females). The Mayo Clinical scoring system (MCS) was used for UC histological activity index (HAI)...