- Osteoarthritis Treatment and Mechanisms
- Peripheral Artery Disease Management
- Rheumatoid Arthritis Research and Therapies
- Mitochondrial Function and Pathology
- Animal Behavior and Reproduction
- Wnt/β-catenin signaling in development and cancer
- Parasite Biology and Host Interactions
- Peroxisome Proliferator-Activated Receptors
- Total Knee Arthroplasty Outcomes
- Hip and Femur Fractures
- Protease and Inhibitor Mechanisms
- Cardiovascular Health and Disease Prevention
- Genetics and Neurodevelopmental Disorders
- Connective tissue disorders research
- Orthopaedic implants and arthroplasty
- Primate Behavior and Ecology
- Pelvic and Acetabular Injuries
- Bone fractures and treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Orthopedic Infections and Treatments
- Metabolism and Genetic Disorders
- Bone and Joint Diseases
Brown University
2023-2024
University of Notre Dame
2018
Abstract: This review compares internal fixation versus arthroplasty in the treatment of nondisplaced femoral neck fractures (FNFs) calling attention to evolving areas consensus that influence clinical decision-making. The Garden classification system, typically dichotomized into (types I and II) displaced III IV) fractures, has been used as a guide for surgical Conventionally, FNF elderly with fixation, hemi-, or more recently total hip, arthroplasty. Studies over last decade have raised...
Osteoarthritis (OA) is now considered as a multifaceted disease affecting various articular tissues, including cartilage, bone, synovium, and surrounding ligaments. The pathophysiology strongly implicates intricate chemical communication, primarily through cytokines, leading to the production of degradative enzymes in inflammatory peptides structural changes resulting characteristic clinical features such joint deformities loss cartilage space seen on X-rays. Recent studies highlight...
Endogenous ochronosis, also known as alkaptonuria, is a rare disease for its bluish-black discoloration of the skin, sclerae, and pinnae, well urine that turns black upon standing. Though rarely fatal, joint degradation common sequela, many patients require multiple large arthroplasties throughout their lifetime. aspects pathophysiological mechanisms have been described, questions remain, such how initiation ochronotic pigmentation prompted specific circumstances make some tissues more...