A5050645681- African Botany and Ecology Studies
- Plant Toxicity and Pharmacological Properties
- Sesquiterpenes and Asteraceae Studies
- Nitric Oxide and Endothelin Effects
- Microwave-Assisted Synthesis and Applications
- Electrochemical Analysis and Applications
- Bee Products Chemical Analysis
- Ethnobotanical and Medicinal Plants Studies
- Insect and Pesticide Research
- Electron Spin Resonance Studies
- Plant and animal studies
- Chemical synthesis and alkaloids
- African cultural and philosophical studies
Walter Sisulu University
2008-2021
University of the Free State
2014
Bindura University of Science Education
2005
Because about 50% of the Zimbabwean population is at risk contracting malaria each year, majority people, especially in rural areas, use traditional plant-based medicines to combat malaria. This explorative ethnobotanical survey was undertaken document how conceptualized and diagnosed by healers, record medicinal plants used prevention treatment malaria, their mode preparation administration. The research conducted three villages Headman Muzite׳s area Chiriga village. These are located...
An antiplasmodial activity-guided isolation was carried out on the dichloromethane extract of Tithonia diversifolia dried leaves. A total five germacranolide type sesquiterpene lactones and a new flavonol, 3,6-dihydroxy-2-(4′-hydroxyphenyl)-7-methoxy-4H-chromen-4-one, were isolated. The flavonol reported an IC50 above 6.00 µM against chloroquine sensitive strain, NF54. antimalarial activity leaf attributed to orizabin tagitinin C.
The stability constant for copper(II) complex with ribose bis(thiosemicarbazone) (log K=18.46±0.15) was determined from UV-Vis data using LETAGROP program. Its interaction nitric oxide studied by spectroscopic and electrochemical techniques. This observed in the spectra as a shoulder around 350 nm an isosbestic point at 420 nm. corresponding equilibrium calculated obtained value K=8.68±0.12), indicates formation of stable nitrosyl complex. Copper(II) bis(thiosemicarbazonato) immobilized on...
The anaesthetic activities of steam distillates Adenia gummifera stem on Apis mellifera were evaluated by a diffusion method. Live, direct and fractional (61–80°C fraction) had greater effect while vacuum mild. activity significantly increased with concentration up to 6% (v/v), then it levelled off, excessive exposure was lethal. number bees in given volume no significant but container (F cal = 66.4; F 3,8 4.07) bee-distillate distance 31.0; 2,6 5.14) did, suggesting the rate active...