A5036539899- Testicular diseases and treatments
- Ubiquitin and proteasome pathways
- Congenital Diaphragmatic Hernia Studies
- Childhood Cancer Survivors' Quality of Life
- Sexual Differentiation and Disorders
- Hernia repair and management
- Vascular Malformations and Hemangiomas
- Pleural and Pulmonary Diseases
- Congenital Anomalies and Fetal Surgery
- Protease and Inhibitor Mechanisms
- Bone fractures and treatments
- Urological Disorders and Treatments
- Pregnancy-related medical research
- Tumors and Oncological Cases
- Retinopathy of Prematurity Studies
- Burn Injury Management and Outcomes
- Clinical Nutrition and Gastroenterology
- Child Nutrition and Feeding Issues
- Elbow and Forearm Trauma Treatment
- Restraint-Related Deaths
- Effects and risks of endocrine disrupting chemicals
- Gastrointestinal disorders and treatments
- Spinal Dysraphism and Malformations
- Abdominal Trauma and Injuries
- Pancreatitis Pathology and Treatment
Medical University of Białystok
2015-2025
ORCID
2020
University of Białystok
2017
Cryptorchidism is the most common congenital birth defect in boys and affects about 2–4% full-term male neonates. Its etiology multifactorial. Purpose . To evaluate serum bisphenol A (BPA) levels with cryptorchidism healthy to assess risk of environmental exposure BPA using authors’ questionnaire. The data were acquired from a study on (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>98</mml:mn></mml:math>) control group...
Research on the markers of immunoregulatory response in multiple sclerosis (MS) is still great importance. The aim our study was evaluation leptin, fibronectin, and UCHL1 concentrations as potential biomarkers a relapsing-remitting type MS (RRMS). Surface Plasmon Resonance Imaging (SPRI) biosensors were used for proteins 100 RRMS patients 46 healthy volunteers. Plasma significantly higher compared to control group (p < 0.001, respectively). concentration revealed highest diagnostic...
to explore the association of plasma concentrations bisphenol A (BPA), S (BPS), and F (BPF) with unilateral cryptorchidism. In addition, analyze selected demographic intraoperative characteristics.Retrospective analysis determine total BPA, BPS BPF using gas chromatography - mass spectrometry (GC-MS) among prepubertal boys cryptorchidism prebupertal male control subjects. During operation, size, turgor location cryptorchid testes were assessed.Plasma BPF.In children cryptorchidism, levels...
Research on the markers of autoimmune response in multiple sclerosis (MS) is still great importance. The aim our study was evaluation plasma 20S constitutive proteasome, immunoproteasome, and cathepsin S concentrations as potential biomarkers a relapsing-remitting type MS (RRMS). Surface plasmon resonance imaging (SPRI) biosensors were used for protein concentrations. Plasma significantly higher RRMS patients compared to control group. All three parameters characterized by excellent...
The aim of this study was to measure the serum AMH (anti-Mullerian hormone) concentrations in a group boys with or without cryptorchidism, evaluation karyotypes, testicular position, morphology, and major length undescended testes. Fifty who were 1-4 years old (median = 2.4 years) unilateral cryptorchidism evaluated. All them underwent orchidopexy 2010. Prior procedure, all subjects had undergone karyotyping exclude chromosomal abnormalities. healthy within same age range 2.1 admitted for...
Ubiquitin-mediated protein degradation plays a crucial role in various cellular processes, including signal transduction, cell differentiation, and stress response. Ubiquitin C-terminal hydrolase 1 (UCHL1) is unique deubiquitinating enzyme that has both ligase activities. The aim of this study was the determination UCHL1 concentration serum children with appendicitis, before after surgery. Material methods: 42 acute who were managed at Pediatric Surgery Department, between 2013 2014,...
The aim of this study was to develop a new, label-free, highly selective Surface Plasmon Resonance Imaging biosensor for the quantitative determination matrix metalloproteinase-2.
The aim of the study is to characterize changes in circulating proteasome (c-proteasome) activity following mild traumatic brain injury children. Fifty children managed at Department Pediatric Surgery because concussion—mild head was randomly included into study. were aged 11 months 17 years (median = 10.07 + −1.91 years). Plasma assessed using Suc-Leu-Leu-Val-Tyr-AMC peptide substrate, 2–6 h, 12–16 and 2 days after injury. Twenty healthy admitted for planned inguinal hernia repair served as...
The aim of the study was to check whether plasma levels brain-derived neurotrophic factor (BDNF), interleukin-8 (IL-8), interleukin-11 (IL-11) and ubiquitin C-terminal hydrolase L1 (UCHL-1) change in children with mild head trauma (N = 29) compared controls 13). Protein concentration (12 concussion without loss consciousness 17 severe consciousness) control group were measured by means Enzyme-Linked Immunosorbent Assay (ELISA) method. IL-8 BDNF statistically higher (9.89 pg/mL 2798.00 pg/mL,...
Primary spontaneous pneumothorax (PSP) occurs at a frequency of 7.4-18 cases per 100 000 population year. The PSP typically in young adults and is uncommon children. aim this study was to review our institutional experience with children.Twenty-two paediatric patients confirmed PSP, treated from 2004 2014 the Paediatric Surgery Clinic. There were 18 boys 4 girls. mean age 16 years, 6 months ± 1 month (range 14-17). body mass index (BMI) 20.1 (ranging 17 24).The recurrence rate 48%. interval...
The ubiquitin-proteasome system regulate p53, caspase and Bcl-2 family proteins, is crucial for the degradation of defective germ cells in testes. Purpose: to evaluate concentration ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) blood plasma boys with cryptorchidism if there any correlation patient age.Patients-50 aged 1-4 years (median = 2,4y.) unilateral cryptorchidism. Exclusion criteria were: previous human chorionic gonadotropin treatment, an abnormal karyotype, endocrine or...