A5073513316- Cerebrovascular and Carotid Artery Diseases
- Polyomavirus and related diseases
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Cardiovascular Health and Disease Prevention
- Bacteriophages and microbial interactions
- Acute Ischemic Stroke Management
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Antenna Design and Analysis
- Medical Imaging Techniques and Applications
- Full-Duplex Wireless Communications
- Intracranial Aneurysms: Treatment and Complications
- Radiation Dose and Imaging
- Advanced Neuroimaging Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Diagnosis and Treatment
- Radiology practices and education
- Plant Virus Research Studies
- Sarcoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Ultrasound in Clinical Applications
- Cardiovascular Disease and Adiposity
- Cutaneous lymphoproliferative disorders research
- Breast Cancer Treatment Studies
Fred Hutch Cancer Center
2016-2025
University of Washington
2016-2025
University of Utah
2015-2025
Nanjing University
2025
University of Washington Medical Center
2013-2024
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa
2024
Hispanics in Philanthropy
2012-2024
Seattle Cancer Care Alliance
2016-2022
Christian Medical College & Hospital
2022
The Mountain Institute
2021-2022
The purpose of this study was to determine whether gadolinium (Gd) is deposited in brain and bone tissues patients receiving only non-Group 1 agents, either macrocyclic or linear protein interacting Gd-based contrast with normal renal function. Group agents are most associated nephrogenic systemic fibrosis that the US Federal Drug Administration has defined as contraindicated at risk for disease.This institutional review board approved Health Insurance Portability Accountability Act...
Although studies have attempted to differentiate intracranial vascular disease using vessel wall magnetic resonance imaging (VWI), none incorporated multicontrast imaging. This study uses T1- and T2-weighted VWI vasculopathies.We retrospectively reviewed patients with clinically defined vasculopathies causing luminal stenosis/irregularity who underwent studies. Two blinded experts evaluated T1 precontrast postcontrast characteristics, including the pattern of thickening; presence, pattern,...
<h3>Importance</h3> Merkel cell carcinoma (MCC) often behaves aggressively; however, disease-recurrence data are not captured in national databases, and it is unclear what proportion of patients with MCC experience a recurrence (estimates vary from 27%-77%). Stage-specific that includes time diagnosis would provide more precise prognostic information contribute to risk-appropriate clinical surveillance. <h3>Objective</h3> To estimate risk stage-specific mortality over since diagnosis....
Abstract A simultaneous noncontrast angiography and intraplaque hemorrhage (SNAP) MR imaging technique is proposed to detect both luminal stenosis in atherosclerosis patients a single scan. Thirteen with diagnosed carotid atherosclerotic plaque were admitted after informed consent. All scans performed on 3T system SNAP, 2D time‐of‐flight magnetization‐prepared 3D rapid acquisition gradient echo sequences. The SNAP sequence utilized phase sensitive acquisition, was designed provide positive...
Background Robust approaches to quantify tumor heterogeneity are needed provide early decision support for precise individualized therapy. Purpose To conduct a technical exploration of longitudinal changes in patterns on dynamic contrast‐enhanced (DCE) magnetic resonance imaging (MRI), diffusion‐weighted (DWI) and FDG positron emission tomography / computed (PET/CT), their association radiation therapy (RT) response cervical cancer. Study Type Prospective observational study with MRI PET/CT...
Compressed sensing-sensitivity encoding is a promising MR imaging acceleration technique. This study compares the image quality of compressed accelerated with conventional sequences.Patients known, treated, or suspected brain tumors underwent 3D T1-echo-spoiled gradient echo T2-FLAIR sequences in addition to corresponding acquisition as part their clinical imaging. Two neuroradiologists blinded sequence and patient information independently evaluated both acquisitions. The were on 4- 5-point...
Although studies have evaluated the differential imaging of moyamoya disease and atherosclerosis, none investigated added value vessel wall magnetic resonance (MRI). This study evaluates diagnostic MRI in differentiating disease, atherosclerotic-moyamoya syndrome (A-MMS), vasculitic-MMS (V-MMS) with a multicontrast protocol.We retrospectively reviewed carotid artery territories patients clinically defined vasculopathies (moyamoya vasculitis) steno-occlusive intracranial disease. Two...
Background and Purpose— Our goal is to determine the added value of intracranial vessel wall magnetic resonance imaging (IVWI) in differentiating nonocclusive vasculopathies compared with luminal alone. Methods— We retrospectively reviewed images from patients both IVWI identify cases clinically defined vasculopathies: atherosclerosis (intracranial atherosclerotic disease), reversible cerebral vasoconstriction syndrome, inflammatory vasculopathy. Two neuroradiologists blinded clinical data...
Background Carotid atherosclerotic plaque rupture is an important source of ischemic stroke. However, the prevalence high‐risk ( HRP ) defined as plaques with luminal surface disruption, a lipid‐rich necrotic core occupying >40% wall, or intraplaque hemorrhage in Chinese population remains unclear. This study uses carotid magnetic resonance imaging CMRI to investigate arteries patients cerebrovascular symptoms. Methods and Results Patients cerebral symptoms anterior circulation within 2...
Background Contrast-enhanced mammography (CEM) and abbreviated breast MRI (ABMRI) are emerging alternatives to standard for supplemental cancer screening. Purpose To compare the diagnostic performance of CEM, ABMRI, MRI. Materials Methods This single-institution, prospective, blinded reader study included female participants referred from January 2018 June 2021. CEM was performed within 14 days MRI; ABMRI produced images. Two readers independently interpreted each after a washout period....
Background The Eastern Cooperative Oncology Group–American College of Radiology Imaging Network Cancer Research Group multicenter A6702 trial identified an optimal apparent diffusion coefficient (ADC) cutoff to potentially reduce biopsies by 21% without affecting sensitivity. Whether this performance can be achieved in clinical settings has not yet been established. Purpose To validate the point-of-care ADC measurements with for reducing unnecessary lesions detected at breast MRI. Materials...
Abstract Approximately one‐third of Merkel cell carcinoma (MCC) patients eventually develop distant metastatic disease. Little is known about whether the location primary lesion predictive initial site, or if survival likelihood differs depending on site. Such data could inform imaging/surveillance practices and improve prognostic accuracy. Multivariate competing‐risk analyses were performed a cohort 215 MCC with metastases, 31% whom had two more sites metastasis. At time metastasis in...
Myelin development during adolescence is becoming an area of growing interest in view its potential relationship to cognition, behavior, and learning. While recent investigations suggest that both white matter (WM) gray (GM) undergo protracted myelination adolescence, quantitative relations between myelin WM GM have not been previously studied. We quantitatively characterized the dependence cortical GM, WM, subcortical density across brain on age, gender, puberty status with use a novel...