A5029879973- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Gout, Hyperuricemia, Uric Acid
- Case Reports on Hematomas
- Lymphoma Diagnosis and Treatment
- Systemic Lupus Erythematosus Research
- Health Systems, Economic Evaluations, Quality of Life
- Spondyloarthritis Studies and Treatments
- Veterinary medicine and infectious diseases
- Biosimilars and Bioanalytical Methods
- Psychometric Methodologies and Testing
- Chronic Lymphocytic Leukemia Research
- Cerebral Palsy and Movement Disorders
- Delphi Technique in Research
- Clinical practice guidelines implementation
- Childhood Cancer Survivors' Quality of Life
- Esophageal Cancer Research and Treatment
- Foot and Ankle Surgery
- Multiple Sclerosis Research Studies
- Gastric Cancer Management and Outcomes
- Traditional Chinese Medicine Studies
- Inflammatory Bowel Disease
- Urticaria and Related Conditions
- Chronic Disease Management Strategies
- Aging and Gerontology Research
Erasmus MC
2024-2025
Erasmus University Rotterdam
2024-2025
University of Twente
2013-2024
Zorginstituut Nederland
2023
Transparency Lab (Netherlands)
2020-2022
Medisch Spectrum Twente
2010-2019
VieCuri Medisch Centrum
2017
KU Leuven
2017
Amsterdam UMC Location Vrije Universiteit Amsterdam
2017
University Medical Center
2017
The Acceptance and Action Questionnaire-II (AAQ-II) is a self-report measure designed to assess experiential avoidance as conceptualized in acceptance commitment therapy (ACT). current study the first evaluate psychometric properties of AAQ-II large sample adults (N = 376) with mild moderate levels depression anxiety who participated on effects an ACT intervention. internal construct validity local measurement precision were investigated by fitting data unidimensional item response theory...
To evaluate the efficacy and safety of anakinra in treating acute gout flares a randomized, double-blind, placebo-controlled, active comparator, non-inferiority (NI) trial.
The implementation of value-based health care in inflammatory arthritis requires a standardized set modifiable outcomes and risk-adjustment variables that is feasible to implement worldwide.The International Consortium for Health Outcomes Measurement (ICHOM) assembled multidisciplinary working group consisted 24 experts from 6 continents, including patient representatives, develop standard arthritis. process followed structured approach, using modified Delphi reach consensus on the following...
Objective. To evaluate the content validity and measurement properties of Patient-Reported Outcome Measurement Information System (PROMIS) physical function item bank a 20-item short form in patients with RA comparison HAQ disability index (HAQ-DI) 36-item Short Form Health Survey (SF-36) functioning scale (PF-10). Methods. The instruments was evaluated by linking their items to International Classification Functioning, Disability (ICF) core set for RA. measures were administered 690...
The added value of measuring patient-reported outcomes (PROs) for delivering patient-centered care and assessment healthcare quality is increasingly evident. However, system wide data collection initiatives are hampered by the proliferation outcome measures (PROMs) conflicting standards. As part a national initiative Dutch Ministry Health, Welfare Sport we developed consensus-based standard set generic PROs PROMs to be implemented across medical specialist care.A working group mandated...
Gout management strategies remain a topic of debate, particularly regarding the efficacy treat-to-target (T2T) and treat-to-avoid-symptoms (T2S) approaches. T2T, endorsed by major rheumatology societies, involves systematic serum urate (sUA) monitoring urate-lowering therapy (ULT) dose escalation to maintain sUA below predefined threshold. In contrast, T2S, which focuses on symptom relief rather than routine monitoring, is supported alternative guidelines. Despite widespread adoption T2T in...
Objective To calibrate the Dutch-Flemish version of PROMIS physical function (PF) item bank in patients with rheumatoid arthritis (RA) and to evaluate cross-cultural measurement equivalence US general population RA data. Methods Data were collected from enrolled Dutch DREAM registry. An incomplete longitudinal anchored design was used where completed all 121 items over course three waves data collection. Item responses fit a generalized partial credit model adapted for parameters examined...
Objective To compare the effectiveness of a strategy administering baricitinib versus one using TNF-inhibitors (TNFi) in patients with rheumatoid arthritis (RA) after conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) failure real-life treat-to-target (T2T) setting. Methods Patients biological and targeted DMARD (b/tsDMARD) naïve RA disease duration ≤5 years without contraindications to b/tsDMARD were randomised either TNFi or when csDMARD failed achieve control T2T...
To retrospectively compare the long-term clinical, functional, and cost outcomes for early RA patients (symptoms < 1 year) who did or not achieve remission in a treat-to-target strategy.Five-year data of 471 included DREAM induction cohort were used. Patients treated according to pre-specified 28-joint Disease Activity Score (DAS28) driven step-up treatment strategy starting with methotrexate, addition sulfasalazine, exchange sulfasalazine biological medication case failure. Two- 3-year...
To compare the measurement properties of HAQ disability index (HAQ-DI), HAQ-II and short form 36 physical functioning scale (PF-10) in patients with gout.A cross-sectional sample 97 gout completed all three measures. Reliability was assessed by examining internal consistency scales. Validity testing for expected intercorrelations associations other aspects health status ability to discriminate between different levels general health. Additionally, distributional were examined.All measures...
Abstract Background The aim of this retrospective study was to examine the longitudinal association between disease activity and radiographic damage in a cohort patients with early RA (symptom onset < 1 year) treated according treat-to-target (T2T) therapy. Methods Baseline 3-year follow-up data were used from included DREAM remission induction cohort. Patients received protocolized T2T treatment, aimed at 28-joint score-erythrocyte sedimentation rate (DAS28-ESR) remission. Disease...
Objective. To compare the psychometric functioning of multidimensional disease-specific, multiitem generic, and single-item measures fatigue in patients with rheumatoid arthritis (RA). Methods. Confirmatory factor analysis (CFA) longitudinal item response theory (IRT) modeling were used to evaluate measurement structure local reliability Bristol RA Fatigue Multi-Dimensional Questionnaire (BRAF-MDQ), Medical Outcomes Study Short Form-36 (SF-36) vitality scale, BRAF Numerical Rating Scales...
Outcomes obtained using different physical function patient reported outcome measures (PROMs) are difficult to compare. To facilitate standardization of measurement and reporting we developed an item response theory (IRT) based standardized score metric for ten commonly used PROMs. Data a total 16,386 respondents from representative cohorts patients with rheumatic diseases as well the Dutch general population were map items PROMs on continuous latent variable. The resulting IRT common was...
To evaluate and compare the measurement precision sensitivity to change of Health Assessment Questionnaire disability index (HAQ DI), Short Form 36 physical functioning scale (PF-10), simulated Patient-Reported Outcomes Measurement Information System (PROMIS) function computer adaptive tests (CATs) with 5, 10, 15 items, using item response theory-based simulation studies.The various instruments was evaluated by calculating root mean square errors (RMSEs) between true levels (latent score)...
Objective To evaluate, from a societal perspective, the incremental cost‐effectiveness of withdrawing tumor necrosis factor inhibitor ( TNF i) treatment compared to continuation these drugs within 1‐year, randomized trial among rheumatoid arthritis patients with longstanding, stable disease activity or remission. Methods Data were collected pragmatic, open‐label trial. Cost‐utility analysis was performed using nonparametric bootstrapping method, and acceptability curve constructed...
Objective. The Social Role Participation Questionnaire (SRPQ) assesses the influence of health on 11 specific roles and 1 general role along 4 dimensions. In this study, a shortened version SRPQ (s-SRPQ) was developed in patients with ankylosing spondylitis (AS) to facilitate data collection clinical studies practice. Methods. Using from 246 AS population controls, fit each different participation dimensions, contribution measurement precision, correlation between dimensions were evaluated...
Abstract Objective To evaluate the current perspectives of patients and health professionals regarding efficacy safety low-dose glucocorticoids (GCs) in RA. Methods Two online surveys were disseminated to professionals, their native language, through national patient organizations rheumatology medical societies, respectively. SurveyMonkey®, MediGuard.org Glucocorticoid Low-dose Outcome RA Study (GLORIA) website used offer deliver these surveys. Results A total 1221 with exposure GCs, 414...
Abstract Background Our objective was to evaluate the effectiveness and cost-effectiveness of positive psychology intervention ‘Happiness Route’ compared an active control condition in a vulnerable population with accumulation health psychosocial problems. Methods We conducted randomized, single-blind, actively-controlled, parallel group study seven municipalities Netherlands. To be eligible, participants had experience loneliness, problems low socio-economic status. Each received several...
Objective To explore the association between achieving favorable clinical outcomes and patients’ perceived change in overall health status after 12 months of treat‐to‐target patients with early rheumatoid arthritis ( RA ) to identify determinants subjective nonimprovement. Methods Baseline 12‐month data included Dutch Rheumatoid Arthritis Monitoring remission induction cohort study at least a moderate response (by European League Against Rheumatism criteria) 1 year were selected for...
Objective. The aim of this study was to identify baseline predictors achieving patient-perceived satisfactory improvement (PPSI) in pain after 6 months treat target patients with early RA. Methods. Baseline and month data were used from included the Dutch Rheumatoid Arthritis Monitoring remission induction cohort study. Simple multivariable logistic regression analyses significant an absolute 30 mm or a relative 50% on visual analogue scale for pain. Results. At months, 125 209 (59.8%)...