Xin Gao

ORCID: 0000-0003-2444-8611
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About
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Research Areas
  • Functional Brain Connectivity Studies
  • Effects and risks of endocrine disrupting chemicals
  • Toxic Organic Pollutants Impact
  • EEG and Brain-Computer Interfaces
  • Advanced Neuroimaging Techniques and Applications
  • Neural dynamics and brain function
  • Dementia and Cognitive Impairment Research
  • Autism Spectrum Disorder Research
  • Advanced MRI Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Neurological disorders and treatments
  • Attention Deficit Hyperactivity Disorder
  • Parkinson's Disease Mechanisms and Treatments
  • Medical Imaging Techniques and Applications
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Cancer Genomics and Diagnostics
  • Renal cell carcinoma treatment
  • Birth, Development, and Health
  • Mental Health Research Topics
  • Estrogen and related hormone effects
  • Cancer, Lipids, and Metabolism
  • Cancer Immunotherapy and Biomarkers
  • Renal and related cancers
  • Health, Environment, Cognitive Aging
  • Per- and polyfluoroalkyl substances research

Shanghai Medical Information Center
2019-2024

University of Electronic Science and Technology of China
2024

The Fourth People's Hospital
2024

Shaoyang University
2024

First Bethune Hospital of Jilin University
2024

Inner Mongolia University
2023

PLA Information Engineering University
2019

Peking Union Medical College Hospital
2017-2019

Xiangya Hospital Central South University
2019

Plastic Surgery Hospital
2019

Abstract 18 F‐Fluorodeoxyglucose positron emission tomography ( F‐FDG PET) is widely employed to reveal metabolic abnormalities linked Parkinson's disease (PD) at a systemic level. However, the individual connectome details with PD based on PET remain largely unknown. To alleviate this issue, we derived novel brain network estimation method for connectome, that is, Jensen‐Shannon Divergence Similarity Estimation (JSSE). Further, intergroup difference between individual's and its global/local...

10.1002/mco2.305 article EN cc-by MedComm 2023-06-27

Automatic optical-to-synthetic aperture radar (SAR) image matching is still a challenging task due to the existence of severe nonlinear radiometric differences between images and presence strong speckles in SAR images. To address this problem, we propose novel feature descriptor called rank-based local self-similarity (RLSS) for optical-to-SAR template matching. The RLSS an improved version (LSS) descriptor, inspired by Spearman's rank correlation coefficient statistics. It can describe...

10.1109/lgrs.2019.2955153 article EN IEEE Geoscience and Remote Sensing Letters 2019-12-05

Abstract The early diagnosis of autism spectrum disorder (ASD) has been extensively facilitated through the utilization resting-state fMRI (rs-fMRI). With rs-fMRI, functional brain network (FBN) gained much attention in diagnosing ASD. As a promising strategy, graph convolutional networks (GCN) provide an attractive approach to simultaneously extract FBN features and facilitate ASD identification, thus replacing manual feature extraction from FBN. Previous GCN studies primarily emphasized...

10.1093/cercor/bhae064 article EN Cerebral Cortex 2024-03-01

Subjective cognitive decline (SCD) is considered the earliest preclinical stage of Alzheimer's disease (AD) that precedes mild impairment (MCI). Effective and accurate diagnosis SCD crucial for early detection timely intervention in AD. In this study, brain functional connectome (i.e., connections graph theory metrics) based on resting-state magnetic resonance imaging (rs-fMRI) provided multiple information about networks has been used to distinguish individuals with from normal controls...

10.3389/fnins.2020.577887 article EN cc-by Frontiers in Neuroscience 2020-09-29

Abstract Functional connectome has revealed remarkable potential in the diagnosis of neurological disorders, e.g. autism spectrum disorder. However, existing studies have primarily focused on a single connectivity pattern, such as full correlation, partial or causality. Such an approach fails discovering complementary topology information FCNs at different connection patterns, resulting lower diagnostic performance. Consequently, toward accurate disorder diagnosis, straightforward ambition...

10.1093/cercor/bhad477 article EN Cerebral Cortex 2023-11-21

Mild cognitive impairment (MCI) is generally considered to be a key indicator for predicting the early progression of Alzheimer's disease (AD). Currently, brain connection (BC) estimated by fMRI data has been validated an effective diagnostic biomarker MCI. Existing studies mainly focused on single pattern neuro-disease diagnosis. Thus, such approaches are commonly insufficient reveal underlying changes between groups MCI patients and normal controls (NCs), thereby limiting their...

10.3389/fcell.2021.782727 article EN cc-by Frontiers in Cell and Developmental Biology 2021-11-22

We aimed to use an individual metabolic connectome method, the Jensen-Shannon Divergence Similarity Estimation (JSSE), characterize aberrant connectivity patterns and topological alterations of individual-level brain predict long-term surgical outcomes in temporal lobe epilepsy (TLE).

10.3389/fcell.2021.803800 article EN cc-by Frontiers in Cell and Developmental Biology 2022-01-11

The functional connectivity network (FCN) has been used to achieve several remarkable advancements in the diagnosis of neuro-degenerative disorders. Therefore, it is imperative accurately estimate biologically meaningful FCNs. Several efforts have dedicated this purpose by encoding biological priors. However, owing high complexity human brain, estimation an 'ideal' FCN remains open problem. To best our knowledge, almost all existing studies lack integration domain expert which limits their...

10.1109/jbhi.2022.3190277 article EN cc-by IEEE Journal of Biomedical and Health Informatics 2022-07-13

Functional connectivity network (FCN) analysis is an effective technique for modeling human brain patterns and diagnosing neurological disorders such as Alzheimer's disease (AD) its early stage, Mild Cognitive Impairment. However, accurately estimating biologically meaningful discriminative FCNs remains challenging due to the poor quality of functional magnetic resonance imaging (fMRI) data our limited understanding brain. Inspired by inter-similarity nature FCNs, similar regions interest...

10.18632/aging.103719 article EN cc-by Aging 2020-09-13

Functional brain network (FBN) provides an effective biomarker for understanding activation patterns and a diagnostic criterion neurodegenerative diseases detections. Unfortunately, it remains challenges to estimate the biologically meaningful or discriminative FBNs accurately, because of poor quality functional magnetic resonance imaging data our limited human brain. In this study, novel FBN estimation model based on group similarity prior was proposed. particular, we extended tensor form...

10.3389/fnins.2020.00165 article EN cc-by Frontiers in Neuroscience 2020-03-10

Subjective cognitive decline (SCD) was considered to be the preclinical stage of Alzheimer's disease (AD). However, less is known about altered rich-club organizations morphological networks in individuals with SCD. This study included 53 SCD and 54 well-matched healthy controls (HC) from Neuroimaging Initiative (ADNI) database. Individual-level brain were constructed by estimating Jensen-Shannon distance-based similarity distribution regional gray matter volume. Rich-club properties then...

10.3389/fnagi.2022.834145 article EN cc-by Frontiers in Aging Neuroscience 2022-02-25

Structural magnetic resonance imaging (sMRI) reveals abnormalities in patients with autism spectrum syndrome (ASD). Previous connectome studies of ASD have failed to identify the individual neuroanatomical details preschool-age individuals. This paper aims establish an morphological method characterize connectivity patterns and topological alterations individual-level brain their diagnostic value ASD.Brain sMRI data from 24 17 normal controls (NCs) were collected; participants both groups...

10.3389/fnins.2022.952067 article EN cc-by Frontiers in Neuroscience 2022-06-28

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces aberrant release of gonadotropins, FSH, and LH blocks ovulation during induced ovarian follicular development in rats by an unknown mechanism. In the current study, TCDD (0, 8, or 32 microg/kg orally) was administered to immature female Sprague-Dawley rats, synchronous 24 h later with equine chorionic gonadotropin (eCG, 5 IU s.c.). Both doses a significant premature increase serum FSH (P < 0.05) at 12 post-eCG. This surge facilitated...

10.1095/biolreprod.102.010439 article EN Biology of Reproduction 2003-06-01

Background: <TEX>$FOXP3^+$</TEX> regulatory T cells (Tregs) inhibit effector cell functions and are implicated in tumour progression. However, together with microvessel density (MVD) they remain controversial prognostic predictors for renal carcinoma (RCC), potential associations have yet to be determined. The objective of this study was determine the significance Tregs MVD their relationship RCCs. Design: Paraffin-embedded tissues from 62 RCC patients were analysed using...

10.7314/apjcp.2012.13.3.867 article EN cc-by Asian Pacific Journal of Cancer Prevention 2012-03-31

Objective Autism spectrum disorder (ASD) is a common neurodevelopmental characterized by the development of multiple symptoms, with incidences rapidly increasing worldwide. An important step in early diagnosis ASD to identify informative biomarkers. Currently, use functional brain network (FBN) deemed for extracting data on imaging Unfortunately, most existing studies have reported utilization information from connection train classifier; such an approach ignores topological and, turn,...

10.3389/fnins.2022.913377 article EN cc-by Frontiers in Neuroscience 2022-05-06
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