Divyajot Sandhu

ORCID: 0000-0003-2445-5803
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Stroke Rehabilitation and Recovery
  • Intracranial Aneurysms: Treatment and Complications
  • Neurological Disorders and Treatments
  • Vascular Malformations Diagnosis and Treatment
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiac Ischemia and Reperfusion
  • Neurosurgical Procedures and Complications
  • Biomarkers in Disease Mechanisms
  • Optical Imaging and Spectroscopy Techniques
  • Pericarditis and Cardiac Tamponade
  • Hospital Admissions and Outcomes
  • Lung Cancer Diagnosis and Treatment
  • Pleural and Pulmonary Diseases
  • Management of metastatic bone disease
  • Dementia and Cognitive Impairment Research
  • Bone and Joint Diseases
  • Trauma and Emergency Care Studies
  • Vascular Anomalies and Treatments
  • Trigeminal Neuralgia and Treatments
  • Emergency and Acute Care Studies
  • Liver Disease and Transplantation
  • Anesthesia and Neurotoxicity Research
  • Neurological Complications and Syndromes

University of South Dakota
2019-2025

Sanford USD Medical Center
2024

University of Sioux Falls
2024

Sanford Health
2019-2023

University of Minnesota System
2020

University of Minnesota
2016

University of Missouri
2013

The pipeline embolization device (PED; Medtronic, MN, USA) can sometimes herniate into the aneurysmal sac in an unexpected manner during or shortly after its deployment due to foreshortening. In this report, we describe 2 endovascular techniques, which be used reposition a herniated PED construct more favorable alignment.In 67-year-old patient who had intraprocedural herniation of giant cavernous aneurysm, stent anchor technique was reverse herniation, reorient construct, and achieve...

10.1159/000452284 article EN Interventional Neurology 2016-11-10

A 24-year-old woman was admitted for seizures. Magnetic resonance imaging revealed a subacute infarct of the right frontal operculum. Transthoracic echocardiogram showed evidence patent foramen ovale (PFO). Further study with transesophageal no PFO, but signs pulmonary arteriovenous malformation (PAVM) that confirmed on ensuing chest CT angiogram. May-Thurner syndrome (MTS) suspected and by magnetic venography showing 70% narrowing left common iliac vein. The PAVM successfully coiled patient...

10.7759/cureus.5141 article EN Cureus 2019-07-15

Stroke survivors and their caregivers report not receiving enough information at discharge. To identify strengths weaknesses of stroke discharge education, we delivered questionnaires that assessed patient caregiver recall, perceived utility, satisfaction as well 1- 3-month follow-up. Categorical data responses were compared between time periods using Fischer exact test. Recall significantly differed (86%) 1-month follow-up (54%, P < .05), but (69%). Patient utility both 1 month (69%) 3...

10.1177/2374373519893201 article EN cc-by-nc Journal of Patient Experience 2019-12-04

Objective To assess the effect of antidepressants on functional post-stroke recovery, we conducted a retrospective analysis among acute ischemic stroke patients with subgroup severe cases, assessing outcomes through 18 months. Methods A retrospectively gathered population was obtained from an institutional database. Grouping via intention-to-treat antidepressant use or lack thereof. Patients (NIHSS ≥ 21) were further analyzed independently. The primary and secondary modified Rankin scale...

10.7759/cureus.5908 article EN Cureus 2019-10-14

Objectives Sublethal, transient occlusion of peripheral vessels, called remote ischemic preconditioning (RIPC), induces a neuroprotective state against brain infarction. Recent studies suggest chronic hypoperfusion in patients with vascular disease (PVD) has analogous effects. We hypothesized positive correlation between the severity and extent neuroprotection. To determine if this exists, we compared stroke volumes clinical measures modified ranking scale (mRS) National Institute Health...

10.7759/cureus.6105 article EN Cureus 2019-11-08

Introduction to ischemic conditioning: In 1986, Murray built upon a series of accumulated works demonstrated that brief “training” episodes fortified cardiac tissue against impending prolonged infarction (Murry et al., 1986). This discovery altered the dogmatic understanding ischemia, highlighting time-dependent compromise during was bimodal, not linear, in nature. Instead being invariably deleterious, an organ’s response ischemia is dependent both duration as well adaptions from previous,...

10.4103/1673-5374.284987 article EN cc-by-nc-sa Neural Regeneration Research 2020-01-01

Objective: To assess the effect of antidepressants on post-ischemic stroke recovery. Background: Antidepressants, namely selective serotonin reuptake inhibitors (SSRIs), have demonstrated efficacy at enhancing post-stroke recovery in trials such as “FLuoxetine for motor After acute ischaeMic strokE” (FLAME) trial. Other studies, including “Effects fluoxetine functional outcomes after stroke” (FOCUS) trial, did not find significant improvements outcomes. In 2015, our institution adopted...

10.1212/wnl.94.15_supplement.128 article EN Neurology 2020-04-14

<h3>Introduction</h3> Reperfusion injury is a recognized but fairly uncommon consequence of revascularization anterior circulation large vessel occlusion. It has not been described in the posterior circulation, perhaps because lower incidence occlusive disease and many these lesions were historically amenable to revascularization. We describe two cases brainstem hemorrhage following vertebrobasilar arterial <h3>Methods</h3> The medical records images patients who underwent reviewed. Cases...

10.1136/neurintsurg-2016-012589.78 article EN cc-by-nc 2016-07-01

OBJECTIVE: The goal of this study was to determine if clinical simulation improved resident's confidence in delivering Acute Stroke(AS)care including patient interaction acute setting,rapid neurological assessment NIHSS and ABCD2 medical decision making.

10.1212/wnl.80.7_supplement.p05.003 article EN Neurology 2013-02-12

OBJECTIVE: To present data which demonstrate that small aneurysms have a higher tendency to rupture than previously thought and are responsible for considerable proportion of subarachnoid hemorrhages seen at our center.

10.1212/wnl.80.7_supplement.p04.089 article EN Neurology 2013-02-12

Introduction Aneurysmal subarachnoid hemorrhage (aSAH) accounts for about 10% of hemorrhagic strokes [1] and holds a high mortality morbidity rate. [2, 3] Vasospasm is one the more devastating complications aSAH. Novel imaging modalities have drastically improved our ability in prompt detection vasospasm these patients. However, clinical management this complication still debated among experts. [4] Systemic cerebral vasodilators are widely used aSAH patients, but guidelines interventional...

10.1161/svin.03.suppl_2.091 article EN cc-by-nc-nd Stroke Vascular and Interventional Neurology 2023-11-01

e24156 Background: Osseous metastases (OMs), a common cause of cancer pain, are only partially palliated by analgesics. Stereotactic body radiotherapy (SBRT) and radiofrequency ablation (RFA) increasingly used, but the comparative effectiveness SBRT vs. RFA for OMs has not been adequately evaluated. Herein we analyzed palliative benefits in terms pain relief from OMs. Methods: A systematic review was performed all studies reporting outcomes (defined as five or fewer fractions radiation)...

10.1200/jco.2020.38.15_suppl.e24156 article EN Journal of Clinical Oncology 2020-05-20

INTRODUCTION: Cortical laminar necrosis (CLN) is a specific pattern of neuronal death due to sparsity glucose and oxygen. These lesions can cause persistent neurological deficits, even after treatment the triggering etiology. Among various causes CLN, data on hepatic encephalopathy manifesting as CLN scarce. Here we report case acute presenting CLN. CASE DESCRIPTION/METHODS: 63 years old lady with history stroke, alcohol abuse nonalcoholic steatohepatitis leading cirrhosis, was brought in...

10.14309/01.ajg.0000712720.58802.83 article EN The American Journal of Gastroenterology 2020-10-01
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