- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Diseases and Immunity
- Liver Disease and Transplantation
- Romani and Gypsy Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Hepatitis Viruses Studies and Epidemiology
- Hepatocellular Carcinoma Treatment and Prognosis
- Parasitic infections in humans and animals
- Parasitic Infections and Diagnostics
- Hemoglobinopathies and Related Disorders
- Gallbladder and Bile Duct Disorders
- Congenital Anomalies and Fetal Surgery
- Esophageal and GI Pathology
- Nutritional Studies and Diet
- Drug Transport and Resistance Mechanisms
- Autopsy Techniques and Outcomes
- Cytomegalovirus and herpesvirus research
- IgG4-Related and Inflammatory Diseases
- Toxoplasma gondii Research Studies
- Pigment Synthesis and Properties
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Polyomavirus and related diseases
- Bartonella species infections research
University of Pavol Jozef Šafárik
2016-2025
Univerzitná Nemocnica Louisa Pasteura
2020-2025
Center for Disease Analysis
2022
General University Hospital in Prague
2016
Background: A 69-year-old man with multiple myeloma and left-sided heart failure presented to the hospital a two-month fever. Method: transjugular liver biopsy was performed due rapid progression of failure. The procedure complicated by an intraperitoneal hemorrhage. bleeding managed expectantly. Result: Significantly elevated serum bilirubin levels occurred on 13th day after biopsy. Increasing were observed until patient’s death biliovenous fistula at site. Simultaneously, his slightly...
Hepatocellular carcinoma (HCC) has multiple molecular classes that are associated with distinct etiologies and, besides particular characteristics, also differ in clinical aspects. We aim to characterize the aspects of alcoholic liver disease-related HCC by a retrospective observational study included all consequent patients diagnosed MRI or histologically verified participating centers from 2010 2016. A total 429 were analysis, which 412 (96%) had cirrhosis at time diagnosis. The most...
Prevalence of Hepatitis B is relatively low in developed European countries. However specific subpopulations may exist within each country with markedly different burden. Roma minority very numerous Slovakia and their lifestyle completely to non-Roma population. The aim this study map prevalence compare it population explore potential socio-economic health related risk factors. Cross-sectional epidemiology was performed that included randomly sampled geographically corresponding random...
Background and Aims . Chronic hepatitis C is a systemic disease type 2 diabetes mellitus (T2DM) belongs to more common extrahepatic. The aim of this study was (i) explore the prevalence impaired fasting glucose (IFG) T2DM in patients with chronic C, (ii) effect direct acting antivirals (DAA) treatment on glycemia, (iii) factors that modulate DAA glycemia C. Methods We performed longitudinal retrospective observational focused undergoing Data about history diabetes, virus, treatment, liver...
Background: The Roma population is one of the largest marginalized groups in Europe. aim our work was to summarize morbidity lifestyle-related diseases and infectious living segregated settlements. Methods: We used data from cross-sectional study HepaMeta, which we examined 452 subjects with an average age 34.7 ± 9.1 years, 35.2% were men, 403 non-Roma 33.5 7.4 45.9% men. collected by means a questionnaire, anthropometric measures, analyzed blood urine samples. Results: had higher incidence...
Background: The simultaneous presence of chronic hepatitis B (CHB) and metabolic syndrome (MS) in the high-risk Roma community constitutes a high risk for liver cirrhosis potentially hepatocellular carcinoma. This study aims to explore relationship between MS CHB. Methods: Data from cross-sectional HepaMeta Study conducted Slovakia 2011 among living rural communities were used. Participants tested MS, lipid levels - total cholesterol, density lipoproteins (HDL), low (LDL), triglycerides...
Background: The Roma population is one of the major marginalized groups in Europe, having higher incidence all spectrums disease and a shorter life expectancy. Yet, reasons for morbidity its exact prevalence were not properly studied. Objectives: objective our study was to compare frequency metabolic syndrome (MetS) people non-Roma Slovakia, levels uric acid correlation with components syndrome. Methods: A group 452 aged 18–55 years, compared control 403 people. data obtained by...
Background: Obesity-induced metabolic syndrome is a multiple risk factor for cardiovascular (CV) factors and type 2 diabetes, ethnic minorities seem to have unfavourable medical in general more frequently than majority populations. Objective: The aim of this study was evaluate the prevalence relation Roma population compared with non-Roma residing eastern part Slovakia. Results: 123 79 patients were evaluated. Men between 40-55 years age had 4.76-times higher odds women 5.26-times sydrome...
Background: Viral hepatitis B and C prevalence in the Roma population of eastern Slovakia is largely unknown. This study aimed to explore associated risk factors chronic viral among living segregated communities Slovakia. Methods: Data from cross-sectional HepaMeta conducted 2011 rural were used. Participants tested for presence HBsAg, anti-HBc IgG anti-HCV. The assessed mainly via a structured questionnaire/interview. Results: Altogether 452 screened, 11 excluded due missing data. A total...
Hepatitis E infection is one of the most frequent causes acute hepatitis in world. Currently five human genotypes with different geographical distributions and distinct epidemiologic patterns are identified. In Slovakia, only rare cases have been reported past years. Because important risk factors associated HEV include consumption contaminated pork meat poor hygienic standards, aim study was to evaluate prevalence anti-HEV total antibodies main for population living separated segregated...