- Synthesis and Biological Evaluation
- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Click Chemistry and Applications
- Nanomaterials for catalytic reactions
- Synthesis of Tetrazole Derivatives
- Quinazolinone synthesis and applications
- Catalytic C–H Functionalization Methods
- Advanced Synthetic Organic Chemistry
- Advanced Photocatalysis Techniques
- Catalytic Cross-Coupling Reactions
- Phenothiazines and Benzothiazines Synthesis and Activities
- Computational Drug Discovery Methods
- Chemical Synthesis and Analysis
- Asymmetric Hydrogenation and Catalysis
- Synthesis and pharmacology of benzodiazepine derivatives
- Synthesis and Characterization of Heterocyclic Compounds
- Recycling and utilization of industrial and municipal waste in materials production
- Ferrocene Chemistry and Applications
- Advancements in Transdermal Drug Delivery
- TiO2 Photocatalysis and Solar Cells
- Advanced Cellulose Research Studies
- Synthesis and Reactivity of Heterocycles
- Advanced Drug Delivery Systems
- Nanoplatforms for cancer theranostics
Banasthali University
2021-2025
Abstract A novel series of 1,4‐triazole and 1 H ‐tetrazole pharmacophoric motifs embellished analogues linked to the privileged 1,4‐benzodiazepine nucleus through an amidophenylene, methylene phenylene spacer were realized prodigiously a domino click reaction. The structures these compounds established on basis their micro analytical IR, HNMR, 13 C NMR Mass spectral data. noteworthy feature this approach, over variety other methods available in literature for preparation 1,4‐regioisomer...
Abstract: Tetrazole is a most versatile pharmacophore of which more than twenty FDAapproved drugs have been marketed globally for the management various diseases. In spite many remarkable and consistent efforts having made by chemists towards development greener sustainable strategies synthesis tetrazole derivatives, this approach still needs attention. The present review focuses on green synthetic preparation derivatives from different starting materials such as nitrile, isonitrile,...
Nitrogen-containing heterocycles attract the attention of chemists due to their multifarious activities. Amongst all, pyrimidine plays a central role and exhibits broad spectrum biological Literature is replete with various aspects synthetic development in chemistry for wide array applications. It aroused our interest compile novel efficient approaches towards synthesis its derivatives. Pyrimidine derivatives are broadly useful as therapeutic agents, owing high degree structural diversity....
The present review focuses on the synthesis of two heteroatoms containing sixmembered heterocyclic compounds, i.e., pyrimidine. In this review, a number pyrimidine derivatives have been illustrated, which show exceptional ability towards clinical practices. Pyrimidine antimicrobial, antibacterial, antifungal, antiallergic, antiinflammatory, anticancer, and anticonvulsant activities. Therefore, researchers are encouraged to synthesize novel, potent, safe, selective that effective against...
A water-assisted cascade reaction has been described to afford a new series of trifluoromethylated dipyridiodiazepinone derivatives as antibacterial agents. This methodology broad substrate scope with minimal waste generation.
A new series of thieno nucleus embellished trinuclear (19, 20) and tetranuclear (21-24) nitrogen heteroaryl have been synthesized by the Suzuki cross-coupling reaction using bis(triphenylphosphine)palladium(II) dichloride. All compounds were characterized IR, 1 H-NMR, 13 CNMR Mass spectral properties. In vitro antibacterial studies compound conducted broth microdilution assay employing Gram-positive Gram-negative strains half-maximal inhibitory concentration (IC50 ) was determined. The...
Abstract: Azepine is a privileged nitrogen-containing ring that has been found to display wide range of biological activities. valuable skeleton in designing novel compounds medicinal chemistry due its interesting chemical and properties. The study on the synthesis this system engenders fascinating area research owing potential form an active pharmacophore for De Novo exploration. In study, conventional domino results were compared access diverse set azepines high yield. approach...
ABSTRACT. Novel five-membered ring (pyrrole, pyrazole and imidazole)-based pyrimidine quinazoline derivatives were synthesized by one-pot domino approach. This approach has the advantages of high yield, mild reaction conditions a simple work-up procedure. The structure compound was elucidated spectroscopy technique elemental analysis. examined for antimicrobial activity against four bacteria (E. coli, S. pyogenes, aureus, P. aeruginosa) two fungi (C. albicans A. clavatus) most exhibited...
<title>Abstract</title> The present study demonstrates the isolation of pure cellulose (CU) from <italic>Cedrus deodar</italic>a <italic>(C. deodara)</italic> wood wool. Further, CU and modified mercaptobenzothiazole-functionalized (CU-MBT) were evaluated for adsorptive removal Hg(II), Pb(II), Cd(II) ions bacterial strains water. Advanced characterizations through TGA, HR-TEM, FE-SEM, FTIR, XRD, EDX XPS performed to analyze adsorbents. adsorption kinetics CU-MBT followed pseudo-second-order...