Spatiotemporal control of singlet oxygen ((1)O2) release is a major challenge for photodynamic therapy (PDT) against cancer with high therapeutic efficacy and minimum side effects. Here selenium-rubyrin (NMe2Se4N2)-loaded nanoparticle functionalized folate (FA) was designed synthesized as an acidic pH-activatable targeted photosensitizer. The nanoparticles could specifically recognize cells via the FA-FA receptor binding were selectively taken up by receptor-mediated endocytosis to enter...

A general strategy for constructing high-effective upconversion nanocapsules based on triplet–triplet annihilation (TTA) was developed by loading both sensitizer and annihilator into BSA–dextran stabilized oil droplets. This can maintain high translational mobility of the chromophores, avoid luminescence quenching chromophore aggregation, decrease O2-induced TTA-based emission. Pt(II)-tetraphenyl-tetrabenzoporphyrin (PtTPBP) BODIPY dyes (BDP-G BDP-Y with maximal fluorescence emission at 528...

A trifunctional photosensitizer was designed to achieve highly selective near-infrared tumor imaging, efficient photodynamic therapy and therapeutic self-monitoring.

Abstract While there have been numerous reports of long‐range polariton transport at room‐temperature in organic cavities, the spatiotemporal evolution propagation is scarcely reported, particularly initial coherent sub‐ps regime, where photon and exciton wavefunctions are inextricably mixed. Hence detailed process exciton‐polariton and, particular, role dark states has remained poorly understood. Here, femtosecond transient absorption microscopy used to directly image motion microcavities...

Abstract The X‐ray crystallographic, optical spectroscopic, and electrochemical properties of a newly synthesized class boron–diindomethene (BDI) dyes their tetrahydrobicyclo precursors (bc‐BDP) are presented. BDI chromophore was designed to show intensive absorption strong fluorescence in an applicationary advantageous spectral range. Its modular architecture permits fusion second subunit, for example, receptor moiety the dye's core yield directly linked yet perpendicularly prearranged...

Two energy transfer cassettes that exhibit a large pseudo Stokes' shift (up to 400 nm) due efficient through-bond 99%) have been constructed. Selective binding of Fe(III) with the donor entity significantly suppresses excitation resulting in fluorescence quenching aqueous solution and living cells.

Abstract Simultaneous targeted cancer imaging, therapy and real‐time therapeutic monitoring can prevent over‐ or undertreatment. This work describes the design of a multifunctional nanomicelle for recognition precise near‐infrared (NIR) therapy. The encapsulates new pH‐activatable fluorescent probe robust NIR photosensitizer, R16FP, is functionalized with newly screened cancer‐specific aptamer targeting viable cells. light up lysosomes imaging. Upon irradiation, R16FP‐mediated generation...

The synthesis and characterization of a highly photostable bromo-substituted BODIPY dye (I) fused-ring-expanded with thienopyrrole moieties is reported. results MTT assays flow cytometric analyses in living HeLa cells demonstrate that I has high singlet oxygen quantum yield (ΦΔ = 0.63) exhibits photocytotoxicity upon irradiation the NIR region making it potentially suitable for use PDT.

A new class of boron−dipyrromethene (BDP or BODIPY) dyes was obtained by phenanthrene fusion to the β-pyrrole positions, absorbing in wavelength range important laser sources. Despite a 'propeller-like' distorted structure crystalline state, chromophore absorbs (log ε ≥ 5) and fluoresces (Φf 0.8) strongly can be easily turned into fluorescence light-up probe. Incorporation latex beads produces bright photostable single-dye Förster Resonance Energy Transfer (FRET) particles for microscopy...

A series of 3-D lanthanide porous coordination polymers, [Ln(6)(BDC)(9)(DMF)(6)(H(2)O)(3)·3DMF](n) [Ln = La, 1; Ce, 2; Nd, 3], [Ln(2)(BDC)(3)(DMF)(2)(H(2)O)(2)](n) Y, 4; Dy, 5; Eu, 6], [Ln(2)(ADB)(3)(DMSO)(4)·6DMSO·8H(2)O](n) 7; Sm, 8; 9; Gd, 10], {[Ce(3)(ADB)(3)(HADB)(3)]·30DMSO·29H(2)O}(n) (11), and [Ce(2)(ADB)(3)(H(2)O)(3)](n) (12) (H(2)BDC benzene-1,4-dicarboxylic acid H(2)ADB 4,4'-azodibenzoic acid), have been synthesized characterized. In 1-3, the adjacent Ln(III) ions are...

Abstract Boron dipyrromethenes (BODIPYs) with bulky triphenylsilylphenyl(ethynyl) and triphenylsilylphenyl substituents on pyrrole sites were prepared via Hagihara–Sonogashira Suzuki–Miyaura cross‐coupling ethynyl‐terminated tetraphenylsilane boronic acid‐terminated tetraphenylsilane. The chromophores are designed to prevent intermolecular π–π stacking interaction enhance fluorescence in the solid state. Single crystals of 1 a 2 b for X‐ray structural analysis obtained, weak interactions...

Two pyrene dimers containing an –O–Si–Si–O− or −O–Si–O− linkage have been designed which exhibit ratiometric excimer/monomer emission upon fluoride anion induced Si–O bond cleavage. Incorporation of the probe into water soluble polymeric nanoparticles enhances its intracellular uptake and displays fluorescent sensing for F− in living cells.

A novel selective fluorescent chemosensor 1 has been synthesized with a phenanthrene-fused dipyrromethene structure. Selective binding of Cu2+ by results in complex that displays high selectivity and sensitivity for H2S. The signal transduction occurs via reversible formation–separation the Cu-1 CuS. Its potential utility biological applications was confirmed fluorescence imaging H2S live cells.

Abstract A series of fused‐ring‐expanded aza‐boradiazaindacene (aza‐BODIPY) dyes have been synthesized by reacting arylmagnesium bromides with phthalonitriles or naphthalenedicarbonitriles. An analysis the structure–property relationships has carried out based on X‐ray crystallography, optical spectroscopy, and theoretical calculations. Benzo 1,2‐naphtho‐fused 3,5‐diaryl aza‐BODIPY display markedly red shifted absorption emission bands in near‐IR region (>700 nm) due to changes energies...

Abstract Considerable achievements on multiple emission capabilities and tunable wavelengths have been obtained in inorganic luminescent materials. However, the development of organic counterparts remains a grand challenge. Herein we report series 2-/2,6-aryl substituted boron-dipyrromethene dyes with wide-range multi-fluorescence emissions across red near infrared their aggregation states. Experimental data X-ray diffraction, UV–vis absorption, room temperature fluorescence spectra proved...

Hybridization of two fluorescent BODIPY dyes in a microcavity is achieved by coupling different exciton transitions to the same cavity mode. We characterize luminescence such hybrid system following nonresonant laser excitation and show that relative population along polariton branches can be controlled changing detuning. This effect used enhance energy transfer states lower branch negatively detuned cavities. compare efficiency via hybridization with dipole–dipole coupling.

Abstract Bose-Einstein condensates of exciton-polaritons in inorganic semiconductor microcavities are known to possess strong interparticle interactions attributed their excitonic component. The play a crucial role the nonlinear dynamics such systems and can be witnessed as energy blueshifts polariton states. However, localised nature Frenkel excitons strongly coupled organic precludes Coulomb exchange-interactions that change mechanisms nonlinearity accordingly. In this report, we unravel...

The preparation of novel stable radical systems that survive and may be manipulated under harsh conditions is essential for their practical applications, such as energy storage conversion materials. Here, we present a facile synthesis an electrically neutral benzo-fused nickel corrole shows remarkable photo- thermal stability. carbon-based organic character was confirmed using electron spin resonance population analyses. This reversibly converted to its aromatic or antiaromatic ion via...

Abstract Open‐shell radicals are promising near‐infrared (NIR) photothermal agents (PTAs) owing to their easily accessible narrow band gaps, but stabilization and functionalization remain challenging. Herein, highly stable π‐extended nickel corrole with [4n+1] π systems synthesized used prepare NIR‐absorbing PTAs for efficient phototheranostics. The light‐harvesting ability of gradually improves as the number fused benzene rings on β‐pyrrolic locations increases radially, naphthalene‐...

Four novel borondipyrromethene (BDP) and -diindomethene (BDI) dyes with one or two (dimethylamino)styryl extensions at the chromophore were synthesized spectroscopically investigated. An X-ray crystal structure shows that extended auxochrome is virtually planar. All thus display intense red/near infrared (NIR) absorption emission. The group induces a charge-transfer character entails bright solvatochromic fluorescence, which only quenched increasing solvent polarity according to energy-gap...