A catalytic system consisting of KI, 18-crown-6, and TBHP for arylsulfonylation activated alkenes with sulfonylhydrazides as sulfonyl precursor is described. This protocol provides a practical environmentally benign method the construction sulfonated oxindoles in water.

Abstract Boron dipyrromethenes (BODIPYs) with bulky triphenylsilylphenyl(ethynyl) and triphenylsilylphenyl substituents on pyrrole sites were prepared via Hagihara–Sonogashira Suzuki–Miyaura cross‐coupling ethynyl‐terminated tetraphenylsilane boronic acid‐terminated tetraphenylsilane. The chromophores are designed to prevent intermolecular π–π stacking interaction enhance fluorescence in the solid state. Single crystals of 1 a 2 b for X‐ray structural analysis obtained, weak interactions...

Cu( ii )-catalyzed divergent synthesis of naphthofurans and benzochromanes through [3 + 2 1] 1 annulations is established.

The self-assembly of metallo-supramolecules has attracted considerable attention in recent decades. These discrete architectures are primarily driven by coordination interactions, typically involving M-N/O (Werner-type) or M-C (organometallic) bonding. However, the use M-π interactions for constructing these multinuclear complexes remains largely unexplored. In this work, we report trinuclear and tetranuclear copper(I) a combination interactions. Cu(I)-NHC were synthesized from...

The synthesis of a series 1,2-diamino-o-carboranes (1-4) is reported. molecular structures these diamino-o-carboranes are remarkable as the inner-cluster C-C bonds all ultra-long (162.7-193.1 pm) and vary substantially with small variations in substituents. results quantum mechanical investigations suggest that origin bond elongation significant in-plane negative hyperconjugation lone pairs nitrogen substituents σ* orbitals o-carboranes.

Chirality widely exists in a diverse array of biologically active molecules and life forms, the catalytic constructions chiral have triggered heightened interest fields chemistry materials pharmaceutical sciences. However, synthesis silicon-stereogenic organosilicon compounds is generally recognized as much more difficult task than that carbon-stereogenic centers because no abundant organosilicon-based sources nature. Herein, we reported highly enantioselective rhodium-catalyzed...

An isolable dicoordinate dialkylsilylene, 2,2,5,5-tetrakis(trimethylsilyl)silacyclopentane-1,1-diyl (6), was found to react with CO2 and ArN═C═X (X = O, S) smoothly give the corresponding bis(silyl)carbonate, 4-imino-1,3-dioxasiletane 4-imino-1,3-dithiasiletane derivatives in high yields, respectively. The molecular structures of these products were determined by X-ray crystallography. All reactions are parallel those a hypercoordinate silylene η5-pentamethylcyclopentadienyl ligands,...

A selective and efficient synthesis of diaryl 1,3,5-oxadiazines was established for the first time from simple readily available amidines in wet DMSO. DMSO employed as a dual carbon synthon water offered oxygen atom to construct oxadiazine ring. The reaction involved two new C–N C–O bond formations.

A new, stable and scalable reagent based on a sulfoxide skeleton for direct deuteriodifluoromethylthiolation has been developed. The displays excellent reactivities toward Tf2O promoted C–H of electron-rich arenes, indoles, alkenes, intramolecular lactonization 2-alkynylbenzoates. Moreover, high deuteration rates good to yields were achieved under metal-free reaction conditions. As result, wide range deuteriodifluoromethylthilolated compounds prepared, enabling further applications in drug discovery.

Because of the three-dimensional bioisosteric feature, bicyclo[1.1.1]pentylamines (BCPAs) are valuable scaffolds in synthetic chemistry and medicinal chemistry. Here, we report a Halogen Atom Transfer (XAT) mediated radical C-N coupling between C3-iodo-BCPs diazonium salts presence base. Similarly, multicomponent reaction (MCR) enables simultaneous construction C-C bond simultaneously. Versatile roles were also explored.

A novel series of disilanylene-bridged BODIPY-based chromophores have been reported.

Non-symmetric thieno[3,2-<italic>b</italic>]thiophene-fused BODIPYs were designed and characterized, further functionalization through the Knoevenagel condensation reaction to form a NIR sensor was achieved.

Abstract A three‐component domino approach for the synthesis of chroman‐spiroquinazolin(thi)ones is described. It involves a condensation 2‐aminoacetophenones and iso(thio)cyanates followed by hetero‐Diels‐Alder annulation with 2‐hydroxybenzyl alcohol derivatives. The reaction exhibits broad substrate scope under metal‐free catalytic condition. magnified image

Direct incorporation of deuterauted functionalizties into molecules has emerged as an attractive approch in organic synthesis. Among them, the selenomethyl is great interest bue still less explored due...

A class of sulfonium ylide-based reagents for electrophilic deuteriodifluoromethylation is reported. Thus, a wide array ubiquitous O-nucleophiles such as sulfonic acid, alcohol, carboxyl and phosphoric acid are deuteriodifluoromethylated, providing straightforward approach to access the OCF2D-functionalizazed scaffolds that otherwise challenging synthesize using conventional methods. This base-free protocol also displays broad functional group compatibility amenable effective late-stage...

Nido -C 2 B 9 carborane anion supported Zn–salen complexes are superior to closo -carborane ones in ROCOP of epoxides and anhydrides.

N-Heterocyclic carbenes (NHCs) have been widely utilized over the past three decades due to their broad applications, yet synthetic methods for preparation remain limited. A promising approach NHC generation involves thermolysis of adducts. Herein, we report synthesis pentafluorobenzene adducts featuring an o-carboranyl group in backbone (2), which, unlike previously studied systems, resists thermal decomposition. Density functional theory (DFT) calculations were used investigate...

An unprecedented eco-friendly multi-component domino approach for the synthesis of spiroquinazolin-2-(thi)ones and quinolin-(thio)ureas <italic>via</italic> Fe(<sc>iii</sc>)-catalyzed double [4 + 2] cycloadditions is described.

The discovery of ferrocene in 1951 was a significant landmark the field organometallic chemistry, and since then, numerous sandwich- or half-sandwich metallic complexes have been reported. However, silver stands as an intriguing exception this regard, knowledge its bonding situation has remained undisclosed. Herein, unprecedented 12-vertex metallacarboranes Ag(I) (2a 2b) were synthesized through reaction sodium hexamethyldisilazide (NaHMDS) with mixture nido-C2B9 carborane anion-supported...

Metallacyclic complexes [(MesC−Cmeth)Pd(L)]2(OTf)4 (MesC−Cmeth = 1,1′-dimesityl-3,3′-methylenediimidazolin-2,2′-diylidene; L 4,4′-dithiodipyridine (L1) (5), 1,2-bis(4-pyridylthio)ethane (L2) (6), 1,3-bis(4-pyridylthio)propane (L3) (7)) were obtained by the self-assembly of [(MesC−Cmeth)Pd(CH3CN)2](OTf)2 with flexible pyridine-based ligands L1−L3 in high yields. The reaction a rigid pyrazine ligand led to formation mononuclear [(MesC−Cmeth)Pd(pyrazine)2](OTf)2 (4), which can be ascribed...

Deprotonation of the bis(imidazolium) salt (1,1′-dimethyl-3,3′-ethylenediimidazolium dibromide, L·2HBr) with silver oxide in a solution mixture CH2Cl2 and CH3OH affords carbene complex [Ag2L2]Cl2 (1, L = 1,1′-dimethyl-3,3′-ethylenediimidazol-2-ylidene). With as only solvent for synthesis after recrystallization chlorinated ambient condition, polymeric [(L·2H)(Ag2Br4)]n (2) was formed. The presence chloride 1 bromide 2 indicates that halogen exchange reaction occurred unambiguously during not...

The reduction of dichloro- and dibromo-cyclopentasilanes with C8K was investigated. A potassium silyl anion a fused tricyclic silane were isolated, respectively. These results indicate that homocyclic silylene intermediate is generated in the dibromocyclopentasilane. trimethylsilyl group bulky enough to protect from dimerization, however, it not good protecting for hindering 1,2-silyl migration.