A5028187134- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Poxvirus research and outbreaks
- Bacillus and Francisella bacterial research
- Public Health in Brazil
- Antimicrobial Resistance in Staphylococcus
- Healthcare Regulation
- SARS-CoV-2 detection and testing
- Infection Control in Healthcare
- COVID-19 Impact on Reproduction
- Bacterial biofilms and quorum sensing
- Antibiotic Use and Resistance
- Virology and Viral Diseases
- Maternal and Neonatal Healthcare
- Vaccine Coverage and Hesitancy
- Bacterial Identification and Susceptibility Testing
- Zoonotic diseases and public health
- Advanced biosensing and bioanalysis techniques
- Health Education and Validation
- Vibrio bacteria research studies
- Biosensors and Analytical Detection
- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Mosquito-borne diseases and control
- Viral Infections and Vectors
Universidade Federal do Rio de Janeiro
2020-2025
Hospital Universitário Clementino Fraga Filho
2020-2025
Universidade de São Paulo
2024
Instituto de Infectologia Emílio Ribas
2019
The incidence of candidemia in our hospital has been stable over an 18-year period (1.3 episodes per 1000 admissions). Since March 2020, we have observed increase cases candidemia.In the was prepared to receive patients with COVID-19, cancellation elective procedures, discharge less sick and activation beds for COVID-19. We compared 2 periods: from January 2019 February 2020 (period 1) September 2).We diagnosed 41 candidemia, 16 1 25 (9 COVID-19 patients). Compared non-COVID-19 patients,...
Abstract ACE2 and TMPRSS2 are key players on SARS-CoV-2 entry into host cells. However, it is still unclear whether expression levels of these factors could reflect disease severity. Here, a case–control study was conducted with 213 positive individuals where cases were defined as COVID-19 patients respiratory distress requiring oxygen support (N = 38) controls those mild to moderate symptoms the who did not need therapy along entire clinical course 175). mRNA evaluated in nasopharyngeal...
Community testing is a crucial tool for the early identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and transmission control. The emergence highly mutated Omicron variant (B.1.1.529) raised concerns about its primary site replication, impacting sample collection detectability by rapid antigen tests. We tested performance Panbio diagnostic test (Ag-RDT) using nasal oral specimens COVID-19 diagnosis in 192 symptomatic individuals, with quantitative...
Background The angiotensin-converting enzyme 2 (ACE2) and the transmembrane serine protease (TMPRSS2) are central human molecules in SARS-CoV-2 virus-host interaction. Evidence indicates that ACE1 may influence ACE2 expression. This study aims to determine whether ACE1, ACE2, TMPRSS2 mRNA expression levels, along with Alu 287 bp polymorphism ( rs4646994 ), contribute severity mortality of COVID-19. Methods Swabs were collected two Brazilian cities 2020: Belo Horizonte n = 134) Rio de Janeiro...
The global reemergence of measles in 2018-2019 reinforces the relevance high-coverage immunization to maintain disease elimination. During an outbreak Sao Paulo State 2019, several cases were reported individuals who adequately vaccinated according current schedule recommends. This study aimed assess IgG antibody seropositivity and titers previously adults. A cross-sectional was conducted at CRIE-HC-FMUSP (Sao Paulo, Brazil) 2019. It included healthy adults had received two or more...
Abstract Background Staphylococcus aureus is one of the leading causes bloodstream infections (BSI) worldwide. In Brazil, hospital-acquired methicillin-resistant S. USA100/SCC mec II lineage replaced previously well-established clones. However, emergence community-associated (CA) MRSA lineages among hospitalized patients an increasing issue. Methods Consecutive isolates recovered from BSI episodes admitted between January 2016 and December 2018 in a Brazilian teaching hospital were tested...
Current guidelines for patient isolation in COVID-19 cases recommend a symptom-based approach, averting the use of control real-time reverse transcription PCR (rRT-PCR) testing. However, we hypothesized that patients with persistently positive results by RT-PCR severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could be potentially infectious prolonged time, even if immunocompetent and asymptomatic, which would demand longer social period than presently recommended. To test this...
Mpox is a zoonotic disease historically reported in Africa. Since 2003, limited outbreaks have occurred outside In 2022, the global spread of cases with sustained interhuman transmission and unusual features raised public health concerns. We explore mpox outbreak Rio de Janeiro (RJ) state, Brazil, an observational study mpox-suspected from June to December 2022. Data collection relied on healthcare notification form. Diagnosis was determined by MPXV-PCR. 46 confirmed cases, anti-OPXV IgG...
Mpox is a zoonotic disease historically reported in Africa. Since 2003, limited outbreaks have occurred outside In 2022, the global spread of cases with sustained interhuman transmission and unusual features raised public health concerns. We explore mpox outbreak Rio de Janeiro (RJ) state, Brazil, an observational study mpox-suspected from June to December 2022. Data collection relied on healthcare notification form. Diagnosis was determined by MPXV-PCR. 46 confirmed cases, anti-VACV IgG...
This study aimed to identify factors associated with colonization by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in adult patients admitted a Brazilian hospital. is cross-sectional study, which underwent nasal swab and were asked about hygiene behavior, habits, clinical history. Among the 702 patients, 180 (25.6%) had S. 21 (2.9%) MRSA. The MRSA attending gym (OR 4.71; 95% CI; 1.42 – 15.06), smoking habit last year 2.37; 0.88 6.38), previous hospitalization...
Em 2003, os primeiros casos de transmissão do vírus monkeypox (MPXV) fora continente Africano foram confirmados em um surto nos EUA. Desde então, esporádicos viajantes retornados da África descritos. No ano 2022, a mpox se disseminou rapidamente por diferentes países e foi declarada emergência saúde pública importância internacional pela OMS. O apresenta manifestações clínicas similares à varíola humana, porém menor intensidade, usualmente lesões cutâneas, evolução sincrônica, associadas ou...
O NEEDIER (Núcleo de Enfrentamento e Estudos Doenças Infecciosas Emergentes Reemergentes) foi importante para o diagnóstico da covid-19 na comunidade UFRJ profissionais saúde segurança pública. Ao longo pandemia, notaram-se mudanças nas características sintomas do público atendido, associados às ondas causadas por diferentes variantes vírus. presente estudo tem como objetivo avaliar as clínicas epidemiológicas população com atendida no nesses diversos períodos. Coorte indivíduos...
Abstract Community testing is a crucial tool for the early identification of SARS-CoV-2 infection and transmission control. The emergence highly mutated Omicron variant (B.1.1.259) raised concerns about its primary site replication, impacting sample collection, detectability by rapid antigens tests. We tested Antigen Rapid Diagnostic Test (Ag-RDT) performance using nasal, oral, saliva specimens COVID-19 diagnosis in 192 symptomatic individuals, RT-qPCR from nasopharyngeal samples as Variant...