A5019414569- Veterinary Equine Medical Research
- Toxoplasma gondii Research Studies
- Vector-borne infectious diseases
- Parasitic Infections and Diagnostics
- Veterinary Orthopedics and Neurology
- Neurological diseases and metabolism
- Helminth infection and control
- Streptococcal Infections and Treatments
- Hereditary Neurological Disorders
- Botulinum Toxin and Related Neurological Disorders
- Diphtheria, Corynebacterium, and Tetanus
- Dermatological diseases and infestations
- Coccidia and coccidiosis research
- Plant Toxicity and Pharmacological Properties
- Insect and Pesticide Research
- Viral Infections and Vectors
- Animal Nutrition and Physiology
- Veterinary Oncology Research
- Spine and Intervertebral Disc Pathology
- Vector-Borne Animal Diseases
- Osteoarthritis Treatment and Mechanisms
- Veterinary Medicine and Surgery
- Viral gastroenteritis research and epidemiology
- Veterinary Pharmacology and Anesthesia
- Reproductive Physiology in Livestock
University of Pennsylvania
2016-2025
University of Nebraska Medical Center
2025
Nebraska Medical Center
2025
Georgia College & State University
2024
Indiana University School of Medicine
2023
Indiana University – Purdue University Indianapolis
2023
Swansea University
2022
United States Army Combat Capabilities Development Command
2021
Stanford University
2011-2018
West Chester University
2012
Borrelia burgdorferi infection is common in horses living Lyme endemic areas and the geographic range for exposure increasing. Morbidity after B. unknown. Documented, naturally occurring syndromes attributed to include neuroborreliosis, uveitis, cutaneous pseudolymphoma. Although other clinical signs such as lameness stiffness are reported horses, these often not well documented. Diagnosis of disease based on burgdorferi, cytology or histopathology infected fluid tissue antigen detection....
Equine neuroborreliosis (NB), Lyme disease, is difficult to diagnose and has limited description in the literature.Provide a detailed of clinical signs, diagnostic, pathologic findings horses with NB.Sixteen histologically confirmed NB.Retrospective review medical records at University Pennsylvania via an ACVIM listserv query inclusion criteria requiring possible exposure Borrelia burgdorferi histologic consistent previous reports NB without evidence other disease.Sixteen were identified, 12...
Abstract OBJECTIVE To determine the prevalence of vitamin E deficiency in horses at admission and time discharge. The hypothesis was that concentrations would decrease during hospitalization. METHODS A prospective cohort study performed client-owned admitted as patients or companions through emergency service a tertiary referral center. Exclusion criteria included supplementation. Whole blood collected into an additive-free tube for all discharge if horse hospitalized minimum 5 days. Serum...
Abstract Objective To determine the accuracy of a dorsal ultrasound-guided approach for perineural injection sixth and seventh cervical spinal nerves (CSNs) with use clinically relevant volume injectate (2 mL). We hypothesized that majority injections would result in identification contrast solution intervertebral foramen (IVF) on CT corresponding methylene blue dye staining CSN postmortem evaluation, distribution into epidural space not occur. Methods 7 horses donated to University...
Vitamin E is a dietary lipid that essential for vertebrate health and fertility. The biological activity of vitamin thought to reflect its ability quench oxygen- carbon-based free radicals thus protect the organism from oxidative damage. However, recent reports suggest may also display other activities. Here, examine possible mechanisms underlie such nonclassical activities E, we investigated possibility it functions as specific modulator gene expression. We show treatment cultured...
Background Recent work demonstrated the value of antigen‐specific antibody indices ( AI and C‐value) to detect intrathecal production against S arcocystis neurona for antemortem diagnosis equine protozoal myeloencephalitis EPM ). Objectives The study was conducted assess whether can be reduced a simple serum : cerebrospinal fluid CSF ) titer ratio achieve accurate diagnosis. Animals Paired samples from 128 horses diagnosed by postmortem examination. sample set included 44 cases, 35...
Background Recent research suggests that serum : CSF titer ratios could provide the most accurate antemortem diagnosis of equine protozoal myeloencephalitis ( EPM ) caused by S arcocystis neurona . Objectives The purpose this study was to assess utility two commercially available tests, indirect fluorescent antibody test IFAT and surface antigen 2, 4/3 ELISA SAG ), using archived paired samples. Animals Samples were obtained from 4 types clinical patients. Confirmed positive cases (n = 9...
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Summary A retrospective study of 43 cases temporohyoid osteoarthropathy was performed to evaluate the epidemiological features and a possible association with crib‐biting. Data collected from records included case details, what diagnostics were utilised, whether medical or surgical treatment administered, outcome. Owners contacted via telephone asked horse had displayed crib‐biting behaviour. Forty‐three horses diagnosed neurological disease associated osteoarthropathy, 62.8% which Quarter...
Abstract Case Description —6 alpaca crias from a single farm were examined because of diarrhea (n = 4) or decreased fecal production 2). Clinical Findings — Cryptosporidium parvum was identified by means flotation in samples 5 the 6 crias, and diagnosis cryptosporidiosis made. In remaining cria, presumptive Three people involved caring for this subsequently confirmed to have cryptosporidiosis, 3 other suspected cryptosporidiosis. Sequence analysis ssu rDNA gene loci C as causative agent 4...
Fibrinous parapneumonic pleural effusions are associated with decreased efficacy of fluid drainage and increased risk medical treatment failure in people, but similar associations have not been established horses.We hypothesized that fibrin deposition the cavity horses increases poor outcome.Seventy four bacterial pleuropneumonia diagnosed by culture cytology tracheal aspirates, fluid, or both, effusion ultrasonographic examination.Retrospective study cases was from 2002 to 2012. Information...
Background Prognosis associated with lymphoma in horses is poorly characterized, and treatment often palliative. Long‐term outcome after chemotherapy for not well documented. Objective To report long‐term of treated chemotherapy. Animals Fifteen equids. Methods Retrospective case series. Medical record search call cases on the ACVIM listserv lymphoma. Results adequate data were identified. Complete remission was achieved 5 (33.3%), partial response 9 equids (60%), stable disease 1 horse....
Confirmation of Borrelia burgdorferi infection in horses has required enzyme-linked immunosorbent assay (ELISA) or Western blot tests performed by reference laboratories. An in-clinic C 6 ELISA SNAP kit been marketed for dogs. This canine was evaluated using serum from experimentally infected ponies. Serum samples originated 2 previous studies. In the first study, 7 ponies were exposed to B. burgdorferi–infected ticks; 4 served as uninfected controls. obtained bimonthly 9 months. second 16...
Antemortem diagnosis of equine protozoal myeloencephalitis (EPM) is challenging. Limited information available regarding a commercial test (surface antigen 1 [SAG-1] ELISA). Performance another (indirect fluorescent antibody [IFAT]) using samples from an independent group has not been well described.The primary goal was to evaluate the SAG-1 ELISA and IFAT naturally occurring EPM cases. A secondary obtain more clinical presentation.Hospital cases were admitted over 20 months classified into...