- Advanced biosensing and bioanalysis techniques
- DNA and Nucleic Acid Chemistry
- RNA Interference and Gene Delivery
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanocluster Synthesis and Applications
- Carbon and Quantum Dots Applications
- Advanced Nanomaterials in Catalysis
- Cell death mechanisms and regulation
- Virus-based gene therapy research
- Sirtuins and Resveratrol in Medicine
- Erythrocyte Function and Pathophysiology
- Ubiquitin and proteasome pathways
- Phytochemistry and Biological Activities
- Medicinal plant effects and applications
- Phytochemistry and biological activity of medicinal plants
- Autophagy in Disease and Therapy
- PARP inhibition in cancer therapy
- Electrochemical sensors and biosensors
- Cancer-related Molecular Pathways
- Toxin Mechanisms and Immunotoxins
- interferon and immune responses
- Phytochemical and Pharmacological Studies
Central South University
2018-2023
Gono University
2023
Changsha University
2018
Currently, prostate cancer is one of the major malignant tumors in males. Recurrence and metastasis are main obstacles that prevent effective treatment cancer. In present study, we aimed to evaluate emodin (EG) against human PC3 DU145 cells. Our study showed EG significantly decreased cell viability cells strikingly induced non-apoptotic death via necroptosis was visualized through colony formation assay, Hoechst 33258 staining, TEM analysis. Furthermore, RNA-sequencing KEGG functional...
A label-free fluorescence assay has been developed for the detection of carcinoembryonic antigen based on dsDNA-templated copper nanoparticles.
Reactive oxygen species are involved in the etiology and progress of many kinds diseases such as cancer, cardiovascular diseases, inflammatory neurodegenerative disorders. Epidemiological studies reported that fruits, vegetables, wines containing a high percentage phenolics flavonoids showed positive impact treating reducing cancer risk, increasing life expectancy.Some Mongolian medicinal plants were studied for their antioxidant activity anticancer effects.Selected plant extracts examined...
Abstract Background Currently, prostate cancer is one of the major malignant tumors for males. Natural products from TCM are acknowledged as excellent anticancer agents to fight sensitive and resistant cancer. We aimed explore potential mechanism molecular targets emodin (EG) against human cells based on RNA-sequencing measures biology techniques. Methods Seven robustaflavones EG isolated Selaginella trichoclada were identified by UV, HRESIMS, 1D/2D NMR spectral Human PC3 DU145 evaluated...