A5089087919- Cell Image Analysis Techniques
- Advanced Fluorescence Microscopy Techniques
- Single-cell and spatial transcriptomics
- Neuroinflammation and Neurodegeneration Mechanisms
Stanford University
2020
The projection targets of a neuronal population are key feature its anatomical characteristics. Historically, tissue sectioning, confocal microscopy, and manual scoring specific regions interest have been used to generate coarse summaries mesoscale projectomes. We present here TrailMap, three-dimensional (3D) convolutional network for extracting axonal projections from intact cleared mouse brains imaged by light-sheet microscopy. TrailMap allows region-based quantification total axon content...
Abstract The projection targets of a neuronal population are key feature its anatomical characterization. Historically, tissue sectioning, confocal microscopy, and manual scoring specific regions interest have been used to generate coarse summaries mesoscale projectomes. We present here TrailMap, 3D convolutional network for extracting axonal projections from intact cleared mouse brains imaged by light-sheet microscopy. TrailMap allows region-based quantification total axon content in large...