A5029031227- Academic Publishing and Open Access
- Epigenetics and DNA Methylation
- Genomics and Chromatin Dynamics
- Social Media in Health Education
- Advanced Topology and Set Theory
- scientometrics and bibliometrics research
- Bioinformatics and Genomic Networks
- Homotopy and Cohomology in Algebraic Topology
- RNA Research and Splicing
- Animal Genetics and Reproduction
- Rings, Modules, and Algebras
- Gene Regulatory Network Analysis
- Advanced Algebra and Logic
- Cellular Mechanics and Interactions
- semigroups and automata theory
- Computability, Logic, AI Algorithms
- Mathematical Dynamics and Fractals
- Microtubule and mitosis dynamics
- Conferences and Exhibitions Management
- Genetics, Aging, and Longevity in Model Organisms
- Retinal Development and Disorders
- Coding theory and cryptography
- Complexity and Algorithms in Graphs
- Microbial Natural Products and Biosynthesis
- Zebrafish Biomedical Research Applications
Eötvös Loránd University
2012-2024
Max Planck Institute of Molecular Cell Biology and Genetics
2017-2023
Company of Biologists
2020-2022
Max Perutz Labs
2015
Vienna Biocenter
2015
University of Vienna
2015
The world continues to face a life-threatening viral pandemic. virus underlying the Coronavirus Disease 2019 (COVID-19), Severe Acute Respiratory Syndrome 2 (SARS-CoV-2), has caused over 98 million confirmed cases and 2.2 deaths since January 2020. Although most recent respiratory pandemic swept globe only decade ago, way science operates responds current events experienced cultural shift in interim. scientific community responded rapidly COVID-19 pandemic, releasing 125,000 COVID-19–related...
Abstract Background Signaling networks in eukaryotes are made up of upstream and downstream subnetworks. The subnetwork contains the intertwined network signaling pathways, while regulatory part transcription factors their binding sites on DNA as well microRNAs mRNA targets. Currently, most databases contain only a subsection this network, making comprehensive analyses highly time-consuming dependent specific data handling expertise. need for detailed mapping systems is also supported by...
Amid the Coronavirus Disease 2019 (COVID-19) pandemic, preprints in biomedical sciences are being posted and accessed at unprecedented rates, drawing widespread attention from general public, press, policymakers for first time. This phenomenon has sharpened long-standing questions about reliability of information shared prior to journal peer review. Does typically withstand scrutiny review, or conclusions likely change version record? We assessed bioRxiv medRxiv that had been subsequently...
Upon fertilization, the genome of animal embryos remains transcriptionally inactive until maternal-to-zygotic transition. At this time, embryo takes control its development and transcription begins. How onset zygotic is regulated unclear. Here, we show that a dynamic competition for DNA binding between nucleosome-forming histones factors regulates zebrafish activation. Taking quantitative approach, found concentration non-DNA-bound core sets time transcription. The reduction in nuclear...
Endocytosis participates in downregulating incoming signals, but 'signaling endosomes' may also serve as physical platforms for crosstalk between signaling pathways. Here, we briefly review the role of endosomes and suggest that endosome-associated scaffold proteins mediate this crosstalk. In addition, using a proteome-wide silico approach - which analyze endosome-binding properties capacity candidates to recruit from more than one distinct pathway extend list putative crosstalk-mediating...
Abstract The world continues to face a life-threatening viral pandemic. virus underlying the COVID-19 disease, SARS-CoV-2, has caused over 98 million confirmed cases and 2.2 deaths since January 2020. Although most recent respiratory pandemic swept globe only decade ago, way science operates responds current events experienced paradigm shift in interim. scientific community responded rapidly pandemic, releasing 125,000 related articles within 10 months of first case, which more than 30,000...
In many organisms, early embryonic development is driven by maternally provided factors until the controlled onset of transcription during zygotic genome activation. The regulation chromatin accessibility and its relationship to gene activity this transition remain poorly understood. Here, we generated maps with ATAC-seq from activation lineage specification. During period, increases at regulatory elements. This increase independent RNA polymerase II-mediated transcription, exception...
Cilia are cellular projections that perform sensory and motile functions. A key ciliary subdomain is the transition zone, which lies between basal body axoneme. Previous work in Caenorhabditis elegans identified two ciliopathy-associated protein complexes or modules direct assembly of zone Y-links. Here, we identify C. CEP290 as a component third module required to form an inner scaffolding structure called central cylinder. Co-inhibition all three completely disrupted structure....
Abstract Amidst the COVID-19 pandemic, preprints in biomedical sciences are being posted and accessed at unprecedented rates, drawing widespread attention from general public, press policymakers for first time. This phenomenon has sharpened longstanding questions about reliability of information shared prior to journal peer review. Does typically withstand scrutiny review, or conclusions likely change version record? We assessed bioRxiv medRxiv that had been subsequently published a through...
In the cytoplasm, filamentous actin (F-actin) plays a critical role in cell regulation, including migration, stress fiber formation, and cytokinesis. Recent studies have shown that filaments form nucleus are associated with diverse functions. Here, using live imaging of an F-actin-specific probe, superfolder GFP-tagged utrophin (UtrCH-sfGFP), we demonstrated dynamics nuclear zebrafish (Danio rerio) embryos. early embryos up to around high stage, UtrCH-sfGFP increasingly accumulated nuclei...
SUMMARY Upon fertilization, the genome of animal embryos remains transcriptionally inactive until maternal-to-zygotic transition. At this time, embryo takes control its development and transcription begins. How onset zygotic is regulated unclear. Here, we show that a dynamic competition for DNA binding between nucleosome-forming histones factors regulates zebrafish activation. Taking quantitative approach, found concentration non-DNA bound core sets time transcription. The reduction in...
ABSTRACT In many organisms, early embryonic development is driven by maternally provided factors until the controlled onset of transcription during zygotic genome activation. The regulation chromatin accessibility and its relationship to gene activity this transition remains poorly understood. Here, we generated maps from activation lineage specification. During period, increases at regulatory elements. This increase independent RNA polymerase II-mediated transcription, with exception...
Using graph spectra, we give a new proof of statement Shparlinski which was the main tool in estimation energy distance set and derive some consequence it. Assuming additional condition, on ener
A given subset $A$ of natural numbers is said to be complete if every element $\N$ the sum distinct terms taken from $A$. This topic strongly connected knapsack problem which known NP complete. The main goal paper study structure sums in a higher dimension. We show 'dense' sets and generalized arithmetic progrssions certain sets.
Abstract We study generic properties of topological groups in the sense Baire category. First, we investigate countably infinite groups. extend a classical result B. H. Neumann, Simmons and A. Macintyre on algebraically closed word problem. Recently, I. Goldbring, S. Kunnawalkam Elayavalli, Y. Lodha proved that every isomorphism class is meager among In contrast, it follows from work W. Hodges model-theoretic forcing there exists comeager abelian present new elementary proof this result....
Let Aη := { 2 n η : = 0, 1, 2, . .}, where 1 ≤ < 2. In the recent paper [Discrete Math.Lett. 4 (2020) 31-36], authors examined subset-sums of set and then presented an encryption algorithm.The basics latter part is that encoded message a public natural number N everyone allowed to query for (Aη Aη) ∩ [1, ] until they find element it.Using results about P (Aη), Aη, it was shown with secret key γ can be decoded in logarithmic time, but eavesdropper without takes on average more than N/log...
The original knapsack problem is well known to be NP-complete. In a multidimensional version one have decide whether $p\in \N^k$ in sumset-sum of set $X \subseteq or not. this paper we are going investigate communication complexity related this.
We prove that the universal solenoid is generic (in sense of Baire category) connected compact metrizable abelian group. also settle dual problem in Pontryagin duality: $(\mathbb{Q},+)$, which solenoid, countably infinite torsion-free