A5079569718- Iron Metabolism and Disorders
- Vitamin D Research Studies
- Pancreatic function and diabetes
- Phytochemicals and Medicinal Plants
- Medicinal Plants and Bioactive Compounds
- Calpain Protease Function and Regulation
- Hemoglobinopathies and Related Disorders
- Medicinal Plants and Neuroprotection
- Cancer, Lipids, and Metabolism
- Biological Stains and Phytochemicals
- Obesity and Health Practices
- Vitamin C and Antioxidants Research
- Lipoproteins and Cardiovascular Health
- Inflammatory mediators and NSAID effects
- Seaweed-derived Bioactive Compounds
- Plant-based Medicinal Research
- Cystic Fibrosis Research Advances
- Obesity, Physical Activity, Diet
- Genetics and Neurodevelopmental Disorders
- Natural Products and Biological Research
- Food Industry and Aquatic Biology
- Prenatal Screening and Diagnostics
- Seed and Plant Biochemistry
- Pharmacological Effects of Natural Compounds
- Biochemical effects in animals
King Saud bin Abdulaziz University for Health Sciences
2017-2024
Armed Forces Hospital
2024
National Guard Health Affairs
2008-2019
King Abdullah International Medical Research Center
2017
King Abdulaziz Medical City
2008-2009
Abstract In this study, a polar extract of Aconitum lycoctonum L. was used for the synthesis silver nanoparticles (AgNPs), followed by their characterization using different techniques and evaluation potential as antioxidants, amylase inhibitors, anti-inflammatory antibacterial agents. The formation AgNPs detected color change, from transparent to dark brown, within 15 min surface resonance peak at 460 nm in UV–visible spectrum. FTIR spectra confirmed involvement various biomolecules AgNP s...
In diabetes mellitus, uncontrolled hyperglycemia has been reported to induce oxidative stress, which may lead health complications. Vitamin D, however, acts as a non-enzymatic antioxidant protect cells against stress and damage.To investigate the antioxidative effect of vitamin D combined with calcium in streptozotocin (STZ)-induced diabetic rats.Rats were divided into four groups (ten rats each group). The first group (control) received normal diet water. second group, including STZ-induced...
Despite being one of the most consumed analgesics worldwide, liver injury is an adverse effect diclofenac (DF). In pursuit reliable hepatoprotective natural remedies, this study aimed to investigate potential protective ferulic acid (FA) and its mechanism against DF‐induced injury. Various network databases datasets were used collect targets corresponding FA Enrichment analyses common performed, a protein‐protein interaction (PPI) was constructed, hub genes identified, upstream miRNA...
Congenital hyperinsulinism (CHI) is a major cause of persistent hypoglycemia and brain damage. Therapeutic strategies to avoid near total pancreatectomy in patients who are unresponsive maximum doses diazoxide octreotide remain be identified, although sirolimus, mammalian target rapamycin (mTOR) inhibitor, has been used successfully treat diffuse type CHI.We sirolimus three infants with CHI. Diagnosis was confirmed clinically, biochemically by genetic testing. Homozygous mutations KCNJ11,...
We report a Saudi girl who presented at birth with neonatal diabetes, duodenal atresia, and progressive cholestasis. After other gene testing was negative, the clinical diagnosis of Mitchell-Riley syndrome ultimately considered further genetic analysis revealed novel missense homozygous variant in RFX6: c.983A>T (p.asp328Val). Despite intensive management, patient died from severe Klebsiella pneumoniae sepsis 5 months age. This rare should be suspected any neonate hyperglycemia complicated...
Around 60% of the world's population uses traditional medicines derived from medicinal plants. Diabetes is a metabolic disorder that manifests as either lack insulin production by pancreatic beta cells or failure body to properly use generated. Fever nut an herb has been used in herbal treatments for many years manage range diseases due its antioxidants, phytochemical, saponin, and polyphenol content The present study was carried out investigate chemical composition therapeutic potential...
Background Sickle cell disease (SCD) is a genetic blood disorder characterized by abnormal hemoglobin S, leading to red deformities, chronic hemolysis, and frequent vaso-occlusive crises (VOC). While advancements in medical care have improved survival rates, adults with SCD continue face substantial challenges their quality of life (QoL) due pain, recurrent VOCs, various complications. This study aimed evaluate the health-related (HRQoL) adult patients aged 14 years above identify key...
We report a case of 36-month-old Saudi girl who presented with recurrent episodes unexplained hypoelectrolytaemia. Her cystic fibrosis CFTR (Cystic Fibrosis Transmembrane conductance Regulator) full gene sequence confirmed that she was homozygous for D579G mutation.
Therapeutic plants and their constituents are increasingly recognized for potential health advantages attracting significant global attention in the context of addressing chronic ailments such as diabetes, cardiovascular disease, cancer. Diabetes is a prevalent condition that has consistent increase its overall prevalence. Quinoa, classified pseudo-cereal, possesses features render it very suitable dietary option those with owing to notable functional advantages. The present study aimed...
Osteoporosis is systematic skeleton disease that defined by low bone mass and changes in structure of tissue, which leads to high risks weak bones fractures. According International Foundation 1 3 women 5 men over the age 50 years are suffering from osteoporosis. Barley grass powder best functional food for supplying nutrients removing toxins human cells, its components have also provided significant health benefits because it contains many such as essential amino acids, fiber, vitamins both...