- Diagnosis and Treatment of Venous Diseases
- Systemic Sclerosis and Related Diseases
- Venous Thromboembolism Diagnosis and Management
- Dermatologic Treatments and Research
- Cerebral Venous Sinus Thrombosis
- Autoimmune Bullous Skin Diseases
- Vascular Malformations Diagnosis and Treatment
- Body Contouring and Surgery
- Cardiac and Coronary Surgery Techniques
- Cardiovascular and Diving-Related Complications
- Peripheral Artery Disease Management
- Bone Tumor Diagnosis and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Coronary Interventions and Diagnostics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Sarcoma Diagnosis and Treatment
- Dupuytren's Contracture and Treatments
- Dermatological and Skeletal Disorders
- Vascular Malformations and Hemangiomas
- Aortic aneurysm repair treatments
- Entomological Studies and Ecology
- Therapeutic Uses of Natural Elements
- Electrospun Nanofibers in Biomedical Applications
- Acute Ischemic Stroke Management
Fondazione Toscana Gabriele Monasterio
2014
University of Pisa
2014
Istituto per lo Studio e la Prevenzione Oncologica
2012
Medico
2012
Azienda Sanitaria Locale Alessandria
2002
Florence (Netherlands)
2002
Fondazione Stella Maris
2002
BACKGROUND Recently a new method of using foam sclerosing agent for the treatment leg veins has been described. We present pilot study technique producing (Tessari's method) (SFT) and its use in sclerotherapy major minor varicosities. OBJECTIVE A preliminary multicenter experience performed by means this kind made purified sodium tetradecylsulfate is The authors evaluated safety efficacy different doses concentrations drug as well methods preparing addition, results were evaluated. METHODS...
Sclerotherapy is the targeted chemical ablation of varicose veins by intravenous injection a liquid or foamed sclerosing drug. The treated may be intradermal, subcutaneous, and/or transfascial as well superficial and deep in venous malformations. aim this guideline to give evidence-based recommendations for foam sclerotherapy.This was drafted on behalf 23 European Phlebological Societies during Guideline Conference 7-10 May 2012 Mainz. conference organized German Society Phlebology. These...
To review the use of sclerosing foam in treatment varicose veins, to describe different techniques preparation, and report complications our 3-year experience with this treatment.From November 1997 end October 2000, 453 patients were treated a for large, medium, minor varicosities sodium tetradecylsulfate (STS) or polidocanol (POL). A first group 257 (90 167 medium large veins) received according Monfreux technique. From December 1999 196 prepared Tessari's method (36 size veins...
BACKGROUND Recently a new method of using foam sclerosing agent for the treatment leg veins has been described. We present pilot study technique producing (Tessari's method) (SFT) and its use in sclerotherapy major minor varicosities. OBJECTIVE A preliminary multicenter experience performed by means this kind made purified sodium tetradecylsulfate is The authors evaluated safety efficacy different doses concentrations drug as well methods preparing addition, results were evaluated. METHODS...
BACKGROUND Recently a new method of using foam sclerosing agent for the treatment leg veins has been described. We present pilot study technique producing (Tessari's method) (SFT) and its use in sclerotherapy major minor varicosities. OBJECTIVE A preliminary multicenter experience performed by means this kind made purified sodium tetradecylsulfate is The authors evaluated safety efficacy different doses concentrations drug as well methods preparing addition, results were evaluated. METHODS...
Objective: To assess the efficacy and safety of sclerotherapy varicose veins (VV) with sclerosing foam (SF) made using Tessari's method (three-way tap two plastic syringes). Design: Two multi-centre prospective clinical series were documented (CS1 CS2). In CS1, which ran from March to December 2000, 177 patients (39 men, 138 women), mean age 56 years, treated in three centres for W related incompetence saphenous veins, recurrence, perforators or collaterals. Conventional duplex-guided was...
Visual and neurological disturbances have always been reported following liquid sclerotherapy (LS) for venous insufficiency. In 1993 Cabrera introduced foam (FS) using a detergent sclerosant as Lauromacrogol 400 or sodium tetradecyl sulphate. Several authors with FS an increased incidence of such transient visual complications. This has associated gas air used to generate the sclerosing foam. The frequent association presence patent foramen ovale, common condition in normal population,...
Foam sclerotherapy has been proven to be a safe and effective treatment for superficial venous insufficiency, but transient visual neurologic disturbances continue reported. These side effects have theorized related the presence of air or gases in sclerosing foam that results "bubble" migration into cerebral circulation. We present differing hypothesis significant amounts endothelin are released from treated veins, capable causing these complications.We tested release 1 (ET-1) 12 rats after...
1 Florence, Italy Address correspondence and reprint requests to: Alessandro Frullini, MD, FACP, Studio Flebologico, Via Einstein 2A, Incisa Valdarno, Italy, or e-mail: [email protected]. A. MD has indicated no significant interest with commercial supporters.
OBJECTIVE To review the use of sclerosing foam in treatment varicose veins, to describe different techniques preparation, and report complications our 3-year experience with this treatment. METHOD From November 1997 end October 2000, 453 patients were treated a for large, medium, minor varicosities sodium tetradecylsulfate (STS) or polidocanol (POL). A first group 257 (90 167 medium large veins) received according Monfreux technique. December 1999 196 prepared Tessari's method (36 size veins...
The foam sclerotherapy technique has become one of the most commonly used treatments for superficial venous insufficiency. Despite excellent results, few visual/neurologic disturbances have been recently reported; their pathogenesis is still debated but a correlation with endothelin-1 (ET-1) release from treated vein proposed.The purpose this work was to evaluate ET-1 after and investigate effects anti-endothelin drug aminaphtone.As in vitro model, an endothelial cell culture, mimicking...
What little research has been done on methods of venous valve function recovery with radiofrequency had disappointing results. Valvuloplasty some supporters, but the majority physicians do not consider it a valid therapeutic option.To test new method treating varicose veins based their collagen structure. This procedure is thermal treatment, fast, significant shrinking and preservation endothelium.In laboratory, we subjected greater saphenous vein specimens to irradiation blue light-emitting...
Objectives Aminaphtone, a naphtohydrochinone used in the treatment of capillary disorders, may affect oedema chronic venous insufficiency. Aim study is to investigate effect aminaphtone on vascular endothelial permeability vitro and its effects three-dimensional capillary-like structures formed by human umbilical vein cells. Method Human cells were treated with 50 ng/ml VEGF for 2 h 6 h. Permeability assay, VE-cadherin expression Matrigel assay performed. Results VEGF-induced was...
To evaluate the chemical reaction of venous wall to different sclerosing agents, Authors studied level blood histamine concentration before and 8-10 min after sclerotherapy injection into large 3-6 mm subcutaneous varices. A total 45 sessions were studied: a solution iodine 2% was used in 15 (group A), liquid polidocanol B), 0.5% foam C). Histamine basal 4.49, 4.48 4.52 µg/100 mL, respectively, while an increase found 4.50 (102%), 4.42 (99%) 4.46 (100%) respectively. No significant...
Not available
In the literature cases of stroke and transient neurological symptoms have been described after sclerotherapy for chronic venous disease The initial interpretation these phenomena was that a micro air embolism in association with patent foramen ovale. This explanation did not always manage to justify all manifestations. Recent theories demonstrated area sclerosis, significant amount endothelin 1. We carried out retrospective assessment case studies on 540 patients at ten phlebological...