Background/Objectives: Gestational diabetes mellitus (GDM) presents significant risks for both maternal and neonatal health, affecting fetal growth increasing the likelihood of future (DM) development in affected women. The dysregulation metabolic biomarkers, including catestatin, has been implicated GDM pathophysiology. However, clinical significance catestatin remains poorly understood, particularly context different therapeutic approaches. Methods: This observational, prospective,...

Our study aimed to investigate the value of inflammatory indices in predicting latency period until birth patients with preterm premature rupture membranes (PPROM).

Aims: This study aimed to evaluate the perinatal outcomes of patients who underwent cervical cerclage and investigate relationship between these systemic inflammatory indices. Methods: A retrospective was conducted at Ankara Etlik City Hospital November 2022 2023. Patients were divided into three groups based on indication for cerclage: history-indicated (H-IC), ultrasound-indicated (U-IC) physical examination-indicated (PE-IC). The markers neutrophil-to-lymphocyte ratio (NLR),...

Fetal growth restriction (FGR) is a critical pregnancy complication linked to increased perinatal morbidity and mortality. Inflammation plays key role in FGR's pathophysiology, systemic inflammation markers may serve as predictors. This study evaluates the of various indices; immune-inflammation index (SII), inflammatory response (SIRI), pan-immune-inflammation value (PIV), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), monocyte-to-lymphocyte (MLR),...

Background: The aim of this study was to examine the relationship between conventional and novel Doppler parameters, including cerebroplacental ratio (CPR), cerebral–placental–uterine (CPUR), umbilical-to-cerebral (UCR), amniotic-to-umbilical-cerebral (AUCR), with diagnosis preeclampsia (PE) adverse neonatal outcomes in PE cases. Methods: This prospective case-control conducted at Ankara Etlik City Hospital Perinatology Clinic November 2023 May 2024. population divided into two groups: Group...

ABSTRACT Aim This study aims to evaluate the relationship between systemic inflammatory markers, derived from complete blood count (CBC) parameters, and spontaneous preterm labor. By comparing these markers term pregnancies, seeks determine their potential predictive value for adverse neonatal outcomes, including birth weight, APGAR (appearance, pulse, grimace, activity, respiration) scores, intensive care unit (NICU) admission. Methods evaluated in 478 women with labor a gestational...

Objectives: Maternal heart disease is a leading cause of non-obstetric maternal mortality and morbidity, complicating the necessary physiological changes during pregnancy. This study aimed to evaluate perinatal outcomes in pregnancies complicated by disease. Methods: A retrospective analysis was conducted from November 2022 2023 at tertiary care hospital. Ninety-three pregnant women with were included categorized into congenital disease, rheumatic other cardiac conditions. Data on...

Objectives: The aim of this study is to evaluate the effect colchicine use on maternal inflammatory markers and pregnancy outcomes in pregnant women diagnosed with Familial Mediterranean Fever (FMF) receiving therapy. Methods: This retrospective analysis included 42 FMF who underwent treatment 126 healthy controls. Neutrophil/Lymphocyte Ratio (NLR), Platelet/Lymphocyte (PLR), Monocyte/Lymphocyte (MLR) rates blood groups first trimester, obstetric morbidities were compared. Results: patient...

Objectives: This study aimed to evaluate the relationships between maternal and neonatal outcomes Fibrosis-4 Index (FIB-4) Aspartate Aminotransferase-to-Platelet Ratio (APRI) in healthy pregnancies, late-onset preeclampsia (LOP), early-onset (EOP). Methods: A retrospective was conducted on 239 pregnant women diagnosed with EOP (n=62), LOP (n=56), pregnancies (n=121) at Etlik City Hospital. Maternal outcomes, as well APRI, FIB-4 scores were compared. Statistical analyses included ANOVA,...

Background/Objectives: This study evaluated the prognostic value of corpus luteum Doppler findings in predicting pregnancy outcomes patients with threatened abortion, or without subchorionic hemorrhage. Methods: A prospective cohort included 180 pregnant women diagnosed abortion first trimester—120 hemorrhage and 60 Corpus parameters, including systole/diastole ratio, Resistance Index, Pulsatility were measured via transvaginal ultrasonography. Pregnancy categorized as first-trimester...

Background: Preeclampsia is a serious pregnancy complication known to be related the pathophysiology of platelet dysfunction and inflammation. The aim this study was investigate role indices inflammatory markers in preeclampsia their importance predicting adverse neonatal outcomes. Methods: A total 118 cases (84 with mild 34 severe preeclampsia) healthy pregnant women were included study. Blood samples obtained at time diagnosis analyzed for (platelet count (PC), distribution width (PDW),...

Objectives: This study aims to identify the risk factors associated with massive transfusion in obstetric hemorrhage and evaluate their predictive value facilitate early intervention improve maternal outcomes. Methods: A retrospective cohort was conducted on 1305 women who received blood transfusions for at Etlik City Hospital between October 2022 December 2024. Patients were categorized into two groups: those required (≥10 units of products) least one unit transfusion. Demographic,...

This study aimed to assess the predictive value of Diastolic Deceleration Area (DDA), a novel Doppler ultrasound parameter, in detecting adverse neonatal outcomes fetuses with late-onset fetal growth restriction (FGR). While parameters such as cerebroplacental ratio (CPR), umbilicocerebral (UCR), and cerebralplacentaluterine (CPUR) are commonly used for monitoring, their power varies. Given importance cerebral blood flow redistribution adaptation hypoxia, we investigated whether DDA could...

To determine the role of sortilin in pathogenesis preeclampsia by examining serum levels maternal blood. This prospective case-control study was conducted from May to November 2023 at Perinatology Clinic Ankara Etlik City Hospital. The cohort divided into two groups: Group 1 consisted 44 pregnant women diagnosed with preeclampsia, and 2 served as control group, comprising healthy women. groups were matched individually, controls selected based on similar age gestational time sample...

Aims: The aim of this study was to investigate the impact concordance and discordance in fetal sex on maternal, pregnancy, neonatal outcomes dichorionic twin pregnancies. Methods: This retrospective cohort analysis includes DCDA pregnancies delivered at Ankara Etlik City Hospital from January 2023 December 2024. Pregnancies were categorized into three distinct groups according combinations gender: male-male (group 1), female-female 2), male-female 3). Maternal demographic, outcome data...

Aims: The primary aim of the study was to evaluate Doppler parameters focusing on fetal cerebral and placental circulation in gestational diabetes mellitus (GDM) investigate their relationship with maternal glycemic profiles. Methods: A prospective cohort conducted involving 52 pregnant women diagnosed GDM 55 control participants. ultrasonography performed between 34 37 weeks gestation key hemodynamic parameters, including umbilical artery (UA) systolic/diastolic (S/D) ratio, UA pulsatility...

Aims: Abortus imminens (AI) is defined as vaginal bleeding and/or pelvic pain before the 20th week of pregnancy. It affects approximately 20% pregnancies. The HALP score, which integrates hemoglobin, albumin, lymphocyte, and platelet levels, a marker inflammation nutritional status. This study investigates association between score AI its potential role in predicting pregnancy outcomes. Methods: retrospective was conducted at Ankara Etlik City Hospital September 2022 March 2024. A total 254...

Aims: Diabetes mellitus (DM), including gestational (GDM) and pregestational diabetes (pre-GDM), adversely affects maternal fetal outcomes due to hyperglycemia vascular changes. The Caval Aortic Index, a non-invasive measure of blood volume, could provide insights into these complications. In our study, we aimed determine the functional changes in inferior vena cava (IVC) aorta (Ao) diameters as well importance caval aortic index predicting perinatal diabetic pregnant women. Methods: This...

Aims: This study aims to evaluate the effectiveness of diagnostic tests, clinical, and laboratory markers in predicting insulin requirements pregnant women diagnosed with gestational diabetes mellitus (GDM). Additionally, we assessed differences maternal neonatal outcomes between insulin-managed diet-managed GDM patients. Methods: A retrospective analysis was conducted on 406 at Ankara Etlik City Hospital October 2022 December 2024. Patients were categorized based method used: one-step 75 g...

OBJECTIVE: To evaluate maternal Resolvin D1 levels in women with gestational diabetes mellitus (GDM) and investigate the association between perinatal outcomes. STUDY DESIGN: This case-control study included 88 singleton pregnancies, conducted from August 2023 to January 2024, at a tertiary care center. Participants were divided into two groups: 44 pregnant diagnosed GDM comprised group, healthy served as control group. Additionally, group was categorized based on management approach 21...