A5051875592- Circular RNAs in diseases
- MicroRNA in disease regulation
- Inflammatory Myopathies and Dermatomyositis
- Agricultural Innovations and Practices
- Eosinophilic Disorders and Syndromes
- Botany and Plant Ecology Studies
- Sarcoidosis and Beryllium Toxicity Research
- Acute Lymphoblastic Leukemia research
- Rheumatoid Arthritis Research and Therapies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- T-cell and B-cell Immunology
- Ecology and Vegetation Dynamics Studies
- Autoimmune and Inflammatory Disorders Research
- Botany, Ecology, and Taxonomy Studies
- Muscle and Compartmental Disorders
- Immune Cell Function and Interaction
- Organic Food and Agriculture
- Systemic Lupus Erythematosus Research
- Toxin Mechanisms and Immunotoxins
- Signaling Pathways in Disease
- Agricultural Systems and Practices
- Systemic Sclerosis and Related Diseases
Cangzhou Central Hospital
2015-2023
Xinjiang Agricultural University
2022
This study aimed to investigate the effects of miR-613 on proliferation, invasion and apoptosis rheumatoid arthritis synovial fibroblasts (RASFs).Synovial tissue samples were collected from 20 (RA) patients 10 with joint trauma undergoing replacement surgery. The RASFs isolated cultured. MiR-613 DKK1 expression in both tissues cells was detected using quantitative real-time PCR (qRT-PCR). Dual luciferase reporter gene assay employed evaluate effect activity DKK1. Then transfected mimics,...
To explore the effect and mechanism of pirfenidone in inhibiting pulmonary fibrosis connective tissue disease-associated interstitial lung disease (CTD-ILD).From 2018 to 2020, 50 CTD-ILD patients were enrolled clinical study. Based on whether was used during treatment, into group control group. Pulmonary function tests compared before after treatment. Enzyme-linked immunosorbent assay (ELISA) performed detect expression tumor necrosis factor-α (TNF-α), signal transducer activator...
Objective . To develop a targeted drug for the treatment of rheumatoid arthritis. Methods In this study, methotrexate (MTX) was combined with glucosamine (Glu) and modified folic acid (FA) to prepare acid‐glucosamine/methotrexate polymer (FA‐Glu/MTX). The stability, sustained release, cytotoxicity, therapeutic effect were evaluated based on in vitro vivo experiments. Results FA‐Glu/MTX had good low cytotoxicity. addition, results experiments proved that compared MTX, has stronger RA certain...
Livestock can transport seeds long distances by endozoochory due to their large home range and capacity move among different habitats. However, differences in digestive system body size between livestock species may result variations the dispersal of domestic livestock. To test such effects, we explore effects endozoochorous seed Malus sieversii three livestock: cattle, horse, sheep Ili Botany Garden, northwest China. We collected M. fed them horses sheep. After feeding, all from feces every...