Introduction Pancreatic cancer is a truculent disease with limited treatment options and grim prognosis. Immunotherapy has shown promise in treating various types of cancer, but its effectiveness pancreatic been lacking. As result, it crucial to identify markers associated immunological pathways order improve the outcomes for this deadly cancer. The purpose study was investigate diagnostic prognostic significance three markers, CD8, CD68, VISTA, ductal adenocarcinoma (PDAC), most common...

Motivated by the fact that location(s) and structural properties of pinning node(s) affect algebraic connectivity a network with respect to reference value, thereby its dynamic performance, this paper studies application single multiple distributed cooperative secondary control generators (DGs) in an islanded microgrid operation. It is shown selection set based on degree distance leader DG(s) from rest improves transient performance for voltage frequency regulation. The efficacy strategy...

The aim of this study is to examine the impact doping Mg–Zr on CaO derived from natural calcite, which are utilized as heterogeneous catalysts produce biodiesel through transesterification reaction canola oil and methanol. were synthesized via wet impregnation method with varying concentrations (2.5, 5, 7.5, 10 wt%) over (Mg/Zr mass ratio 2:1), followed by calcination at 600 °C. Physicochemical analyses, encompassing XRD, BET, SEM, EDX, TGA, employed for catalyst characterization. samples'...

Background: Sepsis is a severe and life-threatening condition leading to widespread inflammation organ dysfunction. It medical emergency that requires immediate attention treatment. One of the key indicators used assess severity prognosis sepsis lactate level. Another indicator significant difference in level carbon dioxide (CO2) between veins arteries. Methods: In this study, we aimed evaluate differences venous arterial PCO2 levels during first 6 hours treatment septic shock. prospective...

Spontaneous pneumorrhachis and pneumoperitoneum are very rare conditions thatinvolve the presence of air within spinal canal peritoneum, respectively, withoutany traumatic or underlying disease. During Covid-19 pandemic, there have beenreports spontaneous pneumomediastinum occurring in some patients with severecases virus. Herein, we present a case pneumomediastinum,pneumothorax, pneumoperitoneum, pneumoretroperitoneum, pneumorrhachis,and subcutaneous emphysema young male without any past...

For a power grid, false data injection attacks attempt to exploit the configuration and information structure of system, introduce erroneous but conforming values into certain state variables, evade existing detection techniques based on residual testing, leading severe security threat overall system. Accordingly, an enhanced method evading in grids is proposed. Since system can typically be partitioned group microgrids proposed approach shows that (i.e., their boundaries sharing structures)...

To evaluate quality of life (QOL) caregivers severely disabled war survivors and identify variables threatening caregivers' QOL.A cross-sectional study was performed on 532 Iran-Iraq related injured by using Persian version 36-item Short Form Health Survey (SF-36).Caregivers had lower QOL compared to the Iranian female population (p < .001). Caregivers amputees better SF-36 scores two groups chemical warfare ranging from .01 <.001). Caregiving being married at time trauma were independent...

Objective: Septic shock is a response to infection and tissue hypoperfusion which does not respond fluid therapy eventually leads organ dysfunction. Aggressive treatment of broad-spectrum antimicrobial supportive measures are the cornerstones successful treatment. In addition main treatment, there adjunctive therapies. Steroids one treatments have been studied in management refractory septic shock. Despite numerous studies on role steroids mortality severe sepsis shock, still lots...

Objectives: Pain management is an important issue in traumatic patients. The aim of this randomized clinical trial was to compare the analgesic effect intravenous acetaminophen with morphine sulfate patients diaphyseal long bone fracture. Methods: This double-blind carried out academic trauma center Mashhad, Iran, from February October 2013. After primary modalities like limb elevation, ice and splinting, were allocated receive either 15 mg/kg or 0.1 randomly. pain severity measured using a...

Background: Sickle cell disease (SCD) is a congenital hemoglobinopathy. A low Hb level and high hemoglobin-to-hematocrit ratio may lead to the vaso-occlusive crisis in patients, for management of which hyperbaric oxygen, hydration, pain relief therapy are proposed. Objectives: In this study, we sought compare effects morphine ketorolac on relieving painful sickle crisis. Methods: double-blind, randomized clinical trial, recruited 92 SCD patients who referred Emergency Department...

Cyber-security of power systems is vital importance in this decade and the attackers attempt to manipulate data inject malicious state variables divert system. Cyber-attack utilizes information system generate attacking vector order elude tests. The proposed novel approach intends change being exploited by adversary through adding virtual buses network referred as spy nodes. These nodes, including extra measurements fed attacker, are able perceived topology on which attacker depends....

Abstract Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy with an unfavorable outcome. The present research aimed to identify novel biological targets for AML diagnosis and treatment. In this study, we performed in-silico method antisense RNAs (AS-RNAs) their related co-expression genes. GSE68172 was selected from the database of Gene Expression Omnibus compared using GEO2R tool find DEGs. Antisense were all genes that had significant expression survival plot drawn them...

Acute renal colic is one of the most painful situations in patients' life. The best management modality for pain alleviation paramount importance.This study aimed to evaluate effect intravenously administered morphine and oral tamsulosin compared independent use patients with colic.This double-blind clinical trial was conducted on 200 aged 18 55 years referred tertiary level referral hospital. were randomly assigned two groups, A B. subjects group treated hydrochloride capsules, while B...

Background: Approximately 25% of the residents' time in each shift is allocated to educating lower-level assistants and interns.Assistants have played a major role interns' education.Aim: To assess teaching abilities emergency medicine training monitoring medical interns undergraduate students.Methods: This cross-sectional study was performed 2015 at center Imam Reza hospital Mashhad University Medical Sciences.We employed researcher-made questionnaire search capability residents...

Background: On the basis of literature, vitamin D is known as an important medium in bodily immune function, and it therefore may play a role pathogenesis sepsis. Objectives: In this study, we aimed to evaluate relationship between serum levels sepsis severity. Patients Methods: This study was case-control that evaluated adult patients admitted emergency department Imam Reza hospital with suspected These were enrolled case group. addition, healthy individuals without diagnostic criteria...

The Relationship between Emotional Intelligence and Job Stress with Safety Behavior among Work Permit Issuers in One of the Oil Industries

Orotracheal intubation is one of the sure ways to manage airways in critical patients (1, 2). Failed (Failure properly place endotracheal tube (ETT) trachea) a rather common event (3). There have been many techniques confirm proper intubation, but none them are applicable all conditions. Methods such as capnography, tracheal sonography and chest-X-ray, were introduced for verification they their own limitations (4, 5). Given significance airway management, authors focused on secondary method...

Introduction: Shoulder dislocation is the most common presentation of joint in emergency department (ED). Bilateral shoulder seldom happens and often posterior type. It usually occurs due to seizure electric shock. Trauma among causes bilateral anterior dislocation. Here, we present a case attack. Case Presentation: A 21-year-old man presented ED with complaint pain restricted range motion. The patient was under therapy for epilepsy, but discontinued his recent weeks. He had attack while...