A5102992388- Neuroscience and Neural Engineering
- Advanced Memory and Neural Computing
- Nanowire Synthesis and Applications
- EEG and Brain-Computer Interfaces
- Photoreceptor and optogenetics research
- Nanoplatforms for cancer theranostics
- Molecular Communication and Nanonetworks
- Advanced Sensor and Energy Harvesting Materials
- Silicon Nanostructures and Photoluminescence
- Neural dynamics and brain function
- Chronic Lymphocytic Leukemia Research
- Photodynamic Therapy Research Studies
- Airway Management and Intubation Techniques
- Sexual function and dysfunction studies
- Lymphoma Diagnosis and Treatment
- Nanomaterials and Printing Technologies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Muscle activation and electromyography studies
- Transcranial Magnetic Stimulation Studies
- Surgical Sutures and Adhesives
- Periodontal Regeneration and Treatments
- Wireless Body Area Networks
- Integrated Circuits and Semiconductor Failure Analysis
- Tracheal and airway disorders
- Conducting polymers and applications
Incheon National University
2025
Yonsei University
2018-2024
RIKEN Center for Emergent Matter Science
2024
RIKEN
2024
Eulji University
2009-2011
University of Ulsan
2006
Asan Medical Center
2006
Ulsan College
2006
Korea University Medical Center
2003
Abstract Transparent implantable devices have received significant attention in neuroscience and biomedical engineering by combining neural recording optical modalities. Opaque, metal‐based electrode arrays for electrophysiology block imaging cause photoelectric artifacts, making them difficult to integrate with optogenetics. Here, a artifact‐free, highly conductive, transparent poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) array is introduced as promising implants. The...
Numerous wireless optogenetic systems have been reported for practical tether-free optogenetics in freely moving animals. However, most devices rely on battery-powered or coil-powered requiring periodic battery replacement bulky, high-cost charging equipment with delicate antenna design. This leads to spatiotemporal constraints, such as limited experimental duration due life animals' restricted movement within specific areas maintain power transmission. In this study, we present a wireless,...
Understanding brain function is essential for advancing our comprehension of human cognition, behavior, and neurological disorders. Magnetic resonance imaging (MRI) stands out as a powerful tool exploring function, providing detailed insights into its structure physiology. Combining MRI technology with electrophysiological recording system can enhance the functionality through synergistic effects. However, integration neural implants presents challenges because strong electromagnetic (EM)...
In the rapidly evolving field of human-machine interfaces (HMIs), high-resolution wearable electronic skin (e-skin) is essential for user interaction. However, traditional array-structured tactile require increased number interconnects, while soft material–based computational methods have limited functionalities. Here, we introduce a thin and e-skin interfaces, offering high mapping capabilities through electrical impedance tomography (EIT). We employed an organic/inorganic hybrid structure...
Abstract Challenges in the understanding of three-dimensional (3D) brain networks by simultaneously recording both surface and intracortical areas signals remain due to difficulties constructing mechanical design spatial limitations implanted sites. Here, we present a foldable flexible 3D neural prosthetic that facilitates mapping complex circuits with high spatiotemporal dynamics from cortical region. This device is tool map transmission through sophisticatedly designed four penetrating...
Abstract Ultrathin crystalline silicon is widely used as an active material for high‐performance, flexible, and stretchable electronics, from simple passive components to complex integrated circuits, due its excellent electrical mechanical properties. However, in contrast conventional wafer‐based devices, ultrathin silicon‐based electronics require expensive rather complicated fabrication process. Although silicon‐on‐insulator (SOI) wafers are commonly obtain a single layer of silicon, they...
Abstract Photodynamic therapy (PDT) is attracting attention as a next-generation cancer treatment that can selectively destroy malignant tissues, exhibit fewer side effects, and lack pain during treatments. Implantable PDT systems have recently been developed to resolve the issues of bulky expensive conventional implement continuous repetitive treatment. Existing implantable systems, however, are not able perform multiple functions simultaneously, such modulating light intensity, measuring,...
Abstract Simultaneous monitoring of electrophysiology and magnetic resonance imaging (MRI) could guide the innovative diagnosis treatment various neurodegenerative diseases that are previously impossible. However, this technique is difficult because existing metal‐based implantable neural interface for not free from signal distortions its intrinsic susceptibility while performing an MRI implanted area interface. Moreover, brain tissue heating implants generated by radiofrequency field poses...
Simultaneous two-photon imaging and electrophysiological recordings offer considerable potential for advancing neurological research therapies. However, traditional metal-based neural interfaces suffer from photoelectric artifacts, while existing transparent implants rely on opaque interconnect lines to address conductivity limitations. Herein, we developed an optically poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) electrode array with electrodes lines. Through a...
Abstract Ultra-thin Crystalline silicon stands as a cornerstone material in the foundation of modern micro and nano electronics. Despite proliferation various materials including oxide-based, polymer-based, carbon-based, 2D materials, crystal continues to maintain its stronghold, owing superior functionality, scalability, stability, reliability, uniformity. Nonetheless, inherent rigidity bulk leads incompatibility with soft tissues, hindering utilization amid biomedical applications. Because...
Recent progress in the fabricating flexible electronics has been developed significantly due to increased interest of which can be applied enormous fields not only conventional electronic devices but bio/eco devices. Flexible wide range such as display, power storage, solar cells, wearable and healthcare monitoring Recently, are being attached on skin even implanted into human body monitor bio-signals for treatment purpose. To improve electrical characteristic mechanical properties...
Here, we present a protocol for the fabrication of transparent implantable electrode arrays integrating optogenetics and electrophysiology. We describe steps fabricating microelectrodes using conductive polymer poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate). then detail procedures analyzing performance electrodes recording light-evoked neural activities from transgenic mouse. This utilizes photolithography rather than conventional electrodeposition. For complete details on use...
Waldenstrom macroglobulinemia (WM) is a B-cell lymphoproliferative disorder associated with bone marrow involvement of lymphoplasmacytic lymphoma (LPL) and an IgM monoclonal gammopathy. Generally B-lymphocytes in LPL do not express CD5 that important for differential diagnosis disorders. In WM, various renal diseases type I cryoglobulinemia are well described separately, but cryoglobulinemic glomerulonephropathy very rarely reported. A 61-yr-old woman complained generalized edema, cyanosis...
A pseudochylothorax, a chyliform pleural effusion, is rare disease of effusion that contains cholesterol crystals or high lipid content not the result disrupted thoracic duct.Most cases were found in patients with long-standing due to chronic inflammatory disease, such as old tuberculous pleurisy rheumatoid pleurisy.We experienced case pseudochylothorax 74-year-old man, who was being treated for pulmonary tuberculosis and 10 years ago.The diagnosis confirmed on pathological study which...
Fiberoptic bronchoscope guided tracheal intubation is more popular in patient with expected difficult by conventional laryngoscopy. We report a case of smooth fiberoptic under local anesthesia. A 10% lidocaine spray 2-3 puffs pharyngolaryngeal topical anesthesia and 2% injection through 19 gauge epidural catheter (ARROW) placed over the suction channel for laryngeal were sufficient to prevent pain, coughing nausea.
Abstract Photodynamic therapy (PDT) is attracting attention as a next-generation cancer treatment that can selectively destroy malignant tissues, exhibit fewer side effects, and lack pain during treatments. Although implantable PDT systems have recently been developed to resolve the issues of bulky expensive conventional implement continuous repetitive treatment, they only focus on providing function termination. In procedures, monitoring must be done simultaneously. Existing systems,...
Low-Cost Flexible Electronics Multiple generations of ultra-thin crystalline silicon nano/micro-membrane sheets with high areal density can be formed from a single <111> mother wafer using an unusual anisotropic etching technique, which utilized for various electronic applications in flexible devices. More details found article number 2302597 by Ki Jun Yu, John A. Rogers, and co-workers.