A5042319501- Antioxidant Activity and Oxidative Stress
- Phytochemicals and Antioxidant Activities
- Genomics, phytochemicals, and oxidative stress
- Genetics, Aging, and Longevity in Model Organisms
- Biochemical effects in animals
- Fatty Acid Research and Health
- Telomeres, Telomerase, and Senescence
- Nutritional Studies and Diet
- Adipose Tissue and Metabolism
- Sirtuins and Resveratrol in Medicine
- Tryptophan and brain disorders
- Vitamin C and Antioxidants Research
- Free Radicals and Antioxidants
- Circadian rhythm and melatonin
- Metabolomics and Mass Spectrometry Studies
- Skin Protection and Aging
- Muscle metabolism and nutrition
- Medicinal Plants and Bioactive Compounds
- Dietary Effects on Health
- Diet and metabolism studies
- Exercise and Physiological Responses
- Nutrition and Health in Aging
- Frailty in Older Adults
- Nutrition, Genetics, and Disease
- Birth, Development, and Health
University of Molise
2016-2025
Harvard University
2018-2022
University of Sannio
2014
University of Maryland, Baltimore
2014
Objective: Berries are a rich source of anthocyanins, and clinical data suggest that polyphenol-rich diet may exert health-promoting effects by reducing oxidative stress. The aim this study was to elucidate the dietary supplementation with Delphinol (trademark owned MNL Chile) standardized maqui berry (Aristotelia chilensis) extract on products lipid peroxidation in healthy, overweight, smoker subjects.Methods: In double-blind, placebo-controlled design, 42 participants (age 45–65 years)...
Abstract Ageing is a challenge for any living organism and human longevity complex phenotype. With increasing life expectancy, maintaining long-term health, functionality well-being during ageing has become an essential goal. To increase our understanding of how works, it may be advantageous to analyze the phenotype centenarians, perhaps one best examples successful ageing. Healthy involves interaction between genes, environment, lifestyle factors, particularly diet. Besides evaluating...
Emerging evidence suggests that combinatorial action of numerous biologically active compounds may be a valuable source in variety therapeutic applications. Several nutraceuticals have demonstrated to augment the efficacy pharmacological approaches or provide physiological benefit improve age-related decline. Recently, possibilities anti-ageing interventions multiplied also ameliorate mitochondrial alterations ageing-associated diseases. In this report, we approached novel treatment strategy...
During the last two centuries average lifespan has increased at a rate of approximately 3 months/year in both sexes, hence oldest old people are becoming population with fastest growth Western World. Although life expectancy is increasing dramatically, healthy not going same pace. This underscores importance studies on prevention age-related diseases, order to satisfactorily decrease medical, economic and social problems associated advancing age, related an number individuals autonomous...
Aim of the present study was to assess impact gender on relationship between long-term mortality and clinical frailty. In an observational, longitudinal 10-year mortality, we examined 1284 subjects. The Frailty Staging System used Cox model employed variables independently associated with survival using a backward stepwise algorithm. To investigate possible interactions selected variables, extension multivariable fractional polynomial algorithm adopted. Women were more likely be older, have...
Decreased adult neurogenesis, or the gradual depletion of neural stem cells in neurogenic niches, is considered a hallmark brain aging. This review provides comprehensive overview intricate relationship between aging, and potential neuroregenerative properties astaxanthin, carotenoid principally extracted from microalga Haematococcus pluvialis. The unique chemical structure astaxanthin enables it to cross blood–brain barrier easily reach brain, where may positively influence neurogenesis....