A5101985513- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Mycobacterium research and diagnosis
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Syphilis Diagnosis and Treatment
- Reproductive tract infections research
- HIV/AIDS drug development and treatment
- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- HIV-related health complications and treatments
- Viral-associated cancers and disorders
- Immunodeficiency and Autoimmune Disorders
- Antibiotic Resistance in Bacteria
- Fungal Infections and Studies
- Infectious Diseases and Mycology
- Infectious Diseases and Tuberculosis
- Antifungal resistance and susceptibility
- Sex work and related issues
- Infectious Disease Case Reports and Treatments
- Polyomavirus and related diseases
- Family Caregiving in Mental Illness
- Diabetic Foot Ulcer Assessment and Management
- Immune Cell Function and Interaction
- Full-Duplex Wireless Communications
Minzu University of China
2024-2025
Hangzhou Xixi hospital
2014-2024
Zhejiang University
2021-2024
Zhejiang Chinese Medical University
2022-2024
First Affiliated Hospital of Wannan Medical College
2010-2011
Wannan Medical College
2010-2011
Escherichia coli is a major pathogen responsible for calf diarrhea. However, it has developed resistance to many antimicrobial drugs their inappropriate usage. The bacterial quorum sensing system transmits information between bacteria, it's important in regulating virulence, drug and acid so on. This can found Gram-negative bacteria operates through acyl-homoserine lactone (AHL) signaling molecules. In this study, type I AHL, N-Octanoyl-L-Homoserine (C8), was added E. growth medium...
Introduction Escherichia coli is a major pathogen responsible for calf diarrhea, which has been exacerbated by the irrational and unscientific use of antimicrobial drugs, leading to significant drug resistance. Methods This study focused on isolation identification E. from diarrhea samples in Tongliao area China. Isolation was conducted using selective media, Gram staining, 16S rRNA sequencing. The minimum inhibitory concentration (MIC) determined through microbroth dilution method....
Human immunodeficiency virus (HIV) infection is characterized not only by severe but also persistent inflammation and immune activation. These characteristics persist in people living with HIV (PLHIV) receiving effective antiretroviral therapy (ART) are associated morbidity mortality nonacquired syndrome (AIDS) events. ART can inhibit replication promote reconstitution, which currently the most way to control AIDS. However, despite long-term overall suppression of plasma RNA level, PLHIV...
Background Due to the inability be cultured in vitro , biological characteristics and pathogenicity of Pneumocystis jirovecii remain unclear. Intestinal microflora disorder is related occurrence development various pulmonary diseases. This work explores pathogenesis pneumocystis pneumonia (PCP) acquired immune deficiency syndrome (AIDS) patients from a microbiome perspective, provide better strategies for diagnosis, treatment, prevention PCP. Methods Subjects were divided into three groups:...
We present an AIDS patient coinfected with Cytomegalovirus, Pneumocystis jirovecii pneumonia, nontuberculous mycobacteria, and COVID-19, who finally recovered from the coinfection. The 36-year-old man had two hospitalizations. In first hospitalization, was diagnosed HIV, COVID-19 quickly accurately, corresponding treatment worked well. second hospitalization can be divided into four stages: (1) Persistent fever period; (2) Pulmonary Progression; (3) ICU (4) Pneumothorax period. During...
(NTM) are a group of mycobacteria that commonly found in the environment and can cause disease humans. The symptoms NTM infection be similar to those tuberculosis, making diagnosis challenging. morbidity associated with is increasing, clinical management
Precise prediction of the occurrence complicated perianal abscesses (PAs) in monkeypox (mpox)-infected patients is important for therapeutic optimization. This study sought to identify risk factors PA.
Introduction: Pneumocystis pneumonia (PCP) is one of the most common opportunistic infections in HIV-infected patients. However, coinfection with Tropheryma whipplei infrequent AIDS patients PCP. Case Presentation: We report a 28-year-old male patient coinfected T. and jirovecii diagnosed bronchoalveolar lavage. After sulfamethoxazole–trimethoprim meropenem treatment, showed clinical improvement 2 weeks. Conclusion: Clinicians need to be alert occurrence infection PCP timely diagnosis...
Diagnosis of neurosyphilis is currently based on the cerebrospinal fluid (CSF) assessments and CSF-Venereal Disease Research Laboratory (CSF-VDRL) traditional "gold standard." In real world, CSF CSF-VDRL are not always available. This study aimed to identify noninvasive predictors real-world clinical parameters diagnostic criteria in populations with different HIV status. this retrospective cohort study, syphilis patients statuses hospitalized for screening were retrospectively recruited at...
Abstract This study aimed to compare between the clinical and laboratory characteristics of neurosyphilis those syphilis in human immunodeficiency virus (HIV) positive explore risk factors associated with occurrence HIV infected. In-patients diagnosed co-infection who underwent a lumbar puncture completed cerebrospinal fluid (CSF) examination were divided into group group. The demographic characteristics, symptoms signs, tests 2 groups comparatively analyzed. Logistic regression analysis was...
Neuropsychiatric adverse events (NPAEs) occur frequently in people living with human immunodeficiency virus (PLWH) receiving antiretroviral therapy (ART). This study aimed to assess the dynamic trends and risk factors of NPAEs among PLWH Hangzhou taking efavirenz (EFV)- or dolutegravir (DTG)- elvitegravir (EVG)-based regimens.A total 287 ART-naive were included this study, EFV (400mg)- (n = 122), (600mg)- 37), DTG- 73), EVG-based 47) other ART regimens 8) as initial regimen administered for...
Chlamydia psittaci is the pathogen of psittacosis and infects a wide range birds even humans. Human infection occurs most commonly in those with history contact or poultry. We describe case human immunodeficiency virus infected patient Zhejiang Province for first time. C. was confirmed by nested polymerase chain reaction (PCR) Real-Time PCR. Phylogenetic analysis revealed that sequences from patient's samples clustered genotype A same branch. Our study highlights possibility diagnosing...
Abstract This study aims to develop and evaluate a model predict the immune reconstitution among HIV/AIDS patients after antiretroviral therapy (ART). A total of 502 are randomized training cohort evaluation cohort. Least absolute shrinkage selection operator (LASSO) regression multivariate logistic analysis performed identify indicators establish nomogram for predicting reconstitution. Decision curve (DCA) clinical impact (CIC) used effectiveness nomogram. Predictive factors included white...
This study explores the risk factors for low-level viremia (LLV) occurrence after ART and develops a prediction model.
Kaposi's sarcoma (KS) is a soft tissue lesion that resembles hyperpigmented angiosarcoma and typically associated with human herpesvirus 8 (HHV-8) infection. It most frequently observed in immunocompromised patients, particularly those AIDS, also referred to as HIV-associated (AIDS-KS). The disease progresses rapidly, challenging manage, has high mortality rate. This case report presents patient AIDS-KS who experienced relapse after chemotherapy anthracyclines. Subsequent the same method had...
The role of HIV infection in precipitating different clinical features cryptococcal meningitis (CM) patients remains controversial. One hundred twelve CM living with HIV/AIDS (CM+HIV+ patients) and 112 without (CM+HIV− were enrolled after propensity score matching. Demographic characteristics, symptoms, routine blood tests, biochemical cerebrospinal fluid (CSF) profiles compared between the two groups. Kaplan–Meier analysis Cox proportional hazards model was used to assess 10-week mortality....
As a malignant tumor derived from vascular endothelial cells, Kaposi's sarcoma (KS) is quite common in AIDS patients. Nonspecific clinical symptoms often lead to timely diagnosis or wrong treatment, leading recurrent disease and poor prognosis. Anti-retroviral therapy (ART) could significantly reduce its morbidity aggressiveness. one of the ARTs, liposome anthracyclines are preferred chemotherapy regimen for disseminated KS with multiple organs tissue invasion. The curative effect highly...
To better deliver antiretroviral drugs for treating patients with acquired immune deficiency syndrome (AIDS) poor reconstitution, a novel nanopole capsule was designed in this study. Forty-eight AIDS reconstitution were chosen as subjects to test their state. CD4+ T and Regulatory cells (Treg) infected HIV cultured polyethyleneimine (PEI) polychitosan (PC) drug delivery system efficiency. The infiltration efficiency performed study the of systems, cell numbers Treg calculated evaluate...