A5101569501- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Viral-associated cancers and disorders
- Rabies epidemiology and control
- MicroRNA in disease regulation
- Lymphoma Diagnosis and Treatment
- Marine Invertebrate Physiology and Ecology
- RNA Research and Splicing
- Histiocytic Disorders and Treatments
- Venomous Animal Envenomation and Studies
First Affiliated Hospital of Guangzhou Medical University
2021-2023
Guangzhou Medical University
2021-2023
Sun Yat-sen University
2019-2022
Third Affiliated Hospital of Sun Yat-sen University
2019-2022
Epstein-Barr virus (EBV) is widely recognised to cause various tumours, and EBV-associated gastric carcinoma (EBVaGC) a special type of GC. It has obviously different clinical features pathological manifestations from EBV-negative carcinoma, but its progression remains elusive. The underlying cancer viral infection detected by genome-wide transcriptome analysis been demonstrated in numerous diseases. We performed comparative RNA sequencing identify gene expression signatures between GC...
Abstract Background: Emerging studies have showed that circular RNAs (circRNAs) are important regulators for tumorigenesis by modulating malignant behaviors of tumor cells. However, the functions EBV-encoded circRNAs in EBV-associated gastric carcinoma (EBVaGC) remain poorly understood. Methods: The expression ebv-circRPMS1 EBVaGC tissues, xenografts and cell lines were analyzed BaseScope, qRT-PCR situ hybridization (ISH). effects on (GC) proliferation, apoptosis, migration invasion measured...