A5051304369- Inflammatory Bowel Disease
- Microscopic Colitis
- Diverticular Disease and Complications
- Eosinophilic Esophagitis
- Autoimmune and Inflammatory Disorders
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- Colorectal Cancer Surgical Treatments
- Immunodeficiency and Autoimmune Disorders
- Helicobacter pylori-related gastroenterology studies
- Celiac Disease Research and Management
- Chronic Lymphocytic Leukemia Research
- Diagnosis and treatment of tuberculosis
- Liver Diseases and Immunity
- Adolescent and Pediatric Healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Biosimilars and Bioanalytical Methods
- Pharmaceutical studies and practices
- Tuberculosis Research and Epidemiology
- Autoimmune Bullous Skin Diseases
- Viral gastroenteritis research and epidemiology
- Appendicitis Diagnosis and Management
- Intraperitoneal and Appendiceal Malignancies
- Liver Disease Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
University of Colorado Anschutz Medical Campus
2022-2025
Cleveland Clinic
2018-2024
University of Colorado Denver
2022-2024
Medscape
2023
AbbVie (United States)
2023
Takeda (Japan)
2023
Shionogi (United States)
2023
Bristol-Myers Squibb (Switzerland)
2023
Takeda (United States)
2023
BioFire Diagnostics (United States)
2023
<h3>Importance</h3> Individuals with adenomatous polyps are advised to undergo repeated colonoscopy surveillance prevent subsequent colorectal cancer (CRC), but the relationship between adenomas at and long-term CRC incidence is unclear. <h3>Objective</h3> To compare by adenoma findings. <h3>Design, Setting, Participants</h3> Multicenter, prospective cohort study of participants in Prostate, Lung, Colorectal, Ovarian (PLCO) Cancer randomized clinical trial flexible sigmoidoscopy (FSG)...
We evaluated the real-world effectiveness and safety of ustekinumab (UST) in patients with Crohn's disease (CD).This study used a retrospective, multicenter, multinational consortium UST-treated CD patients. Data included patient demographics, phenotype, activity, treatment history, concomitant medications. Cumulative rates clinical, steroid-free, endoscopic, radiographic remissions were assessed using time-to-event analysis, clinical predictors by multivariate Cox proportional hazard...
Background/Aim: Spondyloarthritis (SpA), the most common extra-intestinal manifestation of inflammatory bowel disease (IBD), is reported in up to 39% patients with IBD. Despite this high prevalence, risk factors for developing SpA IBD are not well described. In study, we aimed determine associated symptoms and their prevalence an cohort. Methods: Two validated screening questionnaires detection (DETAIL = DETection Arthritis Inflammatory boweL diseases, IBIS-Q Identification Questionnaire)...
There are limited data on the postoperative outcomes in Crohn's disease patients exposed to preoperative ustekinumab or vedolizumab. We hypothesised that biologic use is not associated with complications after ileocolic resection.Crohn's who underwent resection over 2009-2019 were identified at a large regional health system. Preoperative within 12 weeks of surgery was categorised as no biologic, anti-tumour necrosis factor, vedolizumab, ustekinumab. The primary endpoint 90-day...
Ileocolic resection for Crohn's disease traditionally does not include a high ligation of the ileocolic pedicle, and most commonly is performed with stapled side-to-side anastomosis. The mesentery has recently been implicated in pathophysiology disease. Two techniques have developed are associated reduced postoperative recurrence: Kono-S anastomosis that excludes diseased extended mesenteric excision resects mesentery. We aimed to assess technical feasibility safety novel combination...
Postoperative recurrence (POR) of Crohn's disease (CD) is common after surgical resection. We aimed to compare biologic type and timing for preventing POR in adult CD patients ileocecal resection (ICR).We performed a retrospective cohort study who underwent an ICR at 2 medical centers. Recurrence was defined by endoscopy (≥ i2b Rutgeerts score) or radiography (active inflammation neoterminal ileum) stratified postoperative prophylactic within 12 weeks following (none, tumor necrosis factor...
Summary There are conflicting data assessing the impact of isolated post‐operative anastomotic inflammation on future disease progression. The aim this study was to determine relative risk severe progression in Crohn’s (CD) patients with disease. Methods Retrospective cohort adult CD undergoing ileocolonic resection between 2009 and 2020. Patients a ileocolonoscopy ≤18 months from surgery ≥1 subsequent were included. Disease activity assessed using modified Rutgeerts’ score (RS). Primary...
Abstract Background Fecal calprotectin (FC) is a reliable predictor of active bowel inflammation in postoperative Crohn’s disease (CD), but cutoffs vary between studies. Recent guidelines recommend cutoff &lt;50 ug/g to avoid routine endoscopy patients at low pretest probability for CD recurrence. We evaluated the performance this threshold real-world cohort after ileocolic resection (ICR). Methods In retrospective study, with post-ICR 2009 2020 FC &gt; 60 days &lt; 1 year...
Abstract Background Inflammatory bowel diseases (IBD) are costly, chronic illnesses. Key cost-drivers of IBD health care expenditures include pharmaceuticals and unplanned care, but evolving treatment approaches have shifted these factors. We aimed to assess changes in cost determine shifts cost-drivers, examine differences by socioeconomic insurance status over time. Methods The Medical Expenditure Panel Survey (MEPS), a nationally representative database that collects data on utilization...
Postoperative recurrence [POR] of Crohn's disease following ileocolonic resection is common. The impact immediate postoperative intra-abdominal septic complications [IASC] on endoscopic and surgical has not been elucidated.To evaluate if IASC associated with an increased risk for POR.This was a retrospective study adult patients undergoing primary anastomosis between 2009 2020. defined as anastomotic leak or abscess within 90 days the date surgery. Multivariable logistic Cox proportional...