Conventional treatment of systemic lupus erythematosus (SLE) and nephritis (LN) is associated with damage accrual, hence increased morbidity rate. Off-label use rituximab (RTX) has shown significant promise in this patient group; however, data are still controversial. We aimed to analyze the outcomes RTX therapy refractory using a meta-analysis approach.Electronic search medical literature was conducted combination relevant keywords retrieve studies on safety efficacy SLE LN patients....

Anti-tumor necrosis factor-alpha induced lupus (ATIL) represents a major diagnostic and therapeutic challenge. Most cases of ATIL are caused by infliximab, followed etanercept adalimumab. Symptoms can range from common, mild cutaneous lesions to rare, serious pleural or pericardial effusions, deep venous thrombosis, life-threatening pneumonitis, neuritis. Constitutional symptoms often present in association with positive autoantibody serology. Diagnosis be considered if there is temporal...

In contrast to most regions of the world where a decline HIV epidemic can be seen, data from Middle East and North Africa (MENA) region suggests increasing incidence among key populations in region. Accurate collection has long been limited by social, cultural, religious taboos. Understanding knowledge levels attitudes toward HIV/AIDS is an important component design adequate culturally appropriate awareness prevention programs. A survey was conducted including 3841 participants during...

Bedside teaching (BST) is a fundamental component of clinical training and an essential tool in the creation competent physician.1-15 Sir William Osler (1849-1919), one Canada’s most renowned physicians, was first to introduce BST medical education 1892. He described modern as something that needed be taught at bedside: “Medicine learned by bedside not classroom.”9 allows physician patient interact bedside; through this physician-patient interaction process, students residents are...

Rheumatoid arthritis (RA) is often not diagnosed or treated quickly enough to alter outcomes. We aimed evaluate the lag times from disease onset first clinical consultation and diagnosis identify factors contributing delayed in Saudi Arabia.This retrospective, multicenter study collected data on 250 patients, six hospitals Arabia, who met 2010 American College of Rheumatology criteria for RA.The patients mean age was 43.3±12.0 years (mean duration: 6.6±5.8 years). The majority were female...

This paper aims to explore the assessment of patients with rheumatologic diseases, especially rheumatoid arthritis (RA), before undergoing orthopedic surgery. Perioperative ensures an early diagnosis patient's medical condition, overall health, co-morbidities, and risk factors associated proposed procedures. allows for proper postoperative management complications drugs such as disease-modifying anti-rheumatic (DMARD) anti-platelets, corticosteroids. The also supports follow up plans,...

To delineate the clinical features and outcomes of dengue infection to guide clinician early diagnosis identification risks factors for hemorrhagic fever. Methods: This study is a retrospective cross-sectional. Clinical records 567 patients with confirmed infection, admitted single hospital in Jeddah, Saudi Arabia, between January 2010 June 2014 were reviewed. Results: Dengue was most common adult males. Sixty-eight percent infections nationals. In addition diagnostic features, leucopenia...

This study investigated medical students' habits and perceptions of learning difficulties during their first year study.A specially-designed questionnaire was answered by 165 second-year science students at Umm Alqura University in Saudi Arabia.Out the 7 listed questionnaire, ranked peer competition first, followed poor English language skills.Male as top difficulty whereas females it fourth.A majority were dissatisfied with passive, lecture-based method teaching wanted curriculum to be...

Early diagnosis and initiation of treatment for inflammatory arthritis can greatly improve patient outcome. We aimed to provide standardized validated criteria use by primary care physicians (PCPs) in the identification individuals requiring referral a rheumatologist.We analyzed predictive value wide variety demographic variables, patient-reported complaints, physical examination results, biomarkers order identify most useful factors indicating requirement referral. Patients this...

Low back pain (LBP) is primarily managed in general practice and commonly underestimated or misdiagnosed by physicians. This article presents comprehensive review for diagnosis evaluation of LBP according to current clinical studies guidelines. Our objectives are define LBP, establish how take a detailed history physically examine it order enable physicians make an appropriate differential identify relevant investigations referrals patients with LBP. The first offers quick description...

Background: National Registries are essential to direct current practice. Rheumatoid arthritis (RA) registries in the middle east and North Africa remain scarcely represented. Objective: To describe a population of Saudi RA patients compare findings internationally reported data. Methods: This is an observational study that was conducted at Doctor Soliman Fakeeh Hospital (DSFH) Arabia. The ran from 2014 2018 using pool 433 patients. Inclusion criteria included adults older than 18 years age...

Current knowledge of patients' preferences for rheumatoid arthritis (RA) treatment is limited. Our goal was to determine the most favorable mode therapy and reasons behind choosing each route among RA patients in Rheumatoid Arthritis Saudi Database (RASD).In this cross-sectional, nationwide, qualitative study, we conducted interviews with 308 assess their preferred (oral, subcutaneous (SC) injection, or intravenous (IV) infusion) choice. The determining factors were evaluated using a...

Vitamin B12 is essential for neurological function and its deficiency associated with many neuropsychiatric disorders. We report the case of a previously healthy 53-year-old male patient presenting delirium multiple findings. Complete blood analysis indicated megaloblastic anemia. All infectious causes were excluded owing to negative cultures (blood urine). Tests human immunodeficiency virus, syphilis, toxoplasma also negative. Metabolic workup showed severe vitamin deficiency, decreased...

Rheumatoid arthritis (RA) is a chronic disabling disease that can jeopardize the ability of affected individuals to participate in paid work. Our objective was evaluate effectiveness 6-month course tumor necrosis factor (TNF) antagonist (adalimumab) on work ability, overall health, and fatigue RA patients.Between October 2012 February 2014, this prospective, observational study enrolled 63 consecutive patients with established adult at outpatient clinics Makkah, Jeddah, Riyadh Abha (Saudi...

Inhibitors of tumor necrosis factor alpha (TNF-α) are current mainstay therapies for rheumatoid arthritis (RA). The decision when to withdraw TNF-α inhibitors after achieving remission and the incidence relapse rates with elective discontinuation both important questions that demand intense survey in these patients. In this meta-analysis we aimed estimate magnitude rate inhibitor RA patients remission.Systematic searches PubMed/MEDLINE, Cochrane Library databases, grey literature...