A renal biopsy represents the gold standard in diagnosis, prognosis, and management of patients with glomerulonephritis. So far, non-invasive elastographic techniques have not confirmed their utility replacing a biopsy; however, new improved software from Hologic Supersonic Mach 30 is promising method for assessing tissue's stiffness viscosity. We investigated whether this elastography technique could reveal tissue fibrosis chronic glomerulonephritis.Two-dimensional-shear wave (SWE) PLUS...

Introduction: Contrast-induced nephropathy (CIN) has emerged as a prevalent and serious complication associated with the administration of iodinated contrast media during diagnostic therapeutic procedures. Given rising global prevalence chronic kidney disease(CKD,) it is crucial to gain deeper understanding risks linked exposure. Therefore, aim this study, conducted at Vascular Surgery Clinic in tertiary hospital Eastern Europe (Timisoara, Romania), assess incidence CIN identify its risk...

Background/Objectives: Chronic kidney disease–mineral and bone disorder (CKD-MBD) systemic inflammation contribute to mortality in hemodialysis (HD) patients. The primary aim of this study was determine whether specific CKD-MBD markers inflammatory biomarkers are associated with increased risk HD Methods: We conducted a retrospective cohort on 63 stage 5D CKD patients undergoing maintenance HD. Serum intact parathyroid hormone (iPTH), soluble Klotho, calcium, phosphorus, 25(OH)D...

Studies published so far using ultrasound-based elastography in the kidneys, lack to prove a clear relationship between kidney shear wave speed (KSWS) and renal disease progression. Taking into account that is highly vascularized organ, present study aims find KSWS vascular factors (blood pressure [BP], arterial stiffness). Our included 38 diabetic patients (mean age 56.52 ± 16.12 years, 19 female, male). KSWS, an indicator of stiffness, was measured point Shear Wave Elastography (pSWE;...

Abstract This study aimed to analyze the utility of bidimensional shear-wave elastography for renal assessment and in prediction chronic kidney disease (CKD). The included 92 subjects: 50 healthy volunteers 42 patients with different degrees CKD (mean age, 57.5 ± 13.4; 50% were female), excluding those undergoing replacement therapies, obstructive pathology, or lithiasis. We performed velocity (KSWV) determinations midportion parenchyma each kidney. median values expressed meters per second....

Klotho is found in two forms: a transmembrane form and soluble (s-Klotho). In order to be excreted, s-Klotho, that too large filtered, will probably reach the proximal convoluted tubule by transcytosis process. The aim of our study was show relationship between levels s-Klotho tubular injury patients with diabetic kidney disease (DKD), using as marker molecule-1 (KIM-1).Our included 63 DKD (stages 1-5, mean eGFR 65.15±32.45ml/min) age 58.13±12 years. all we determined serum of: KIM-1 ELISA,...

Elastography is a useful noninvasive tool for the assessment of renal transplant recipients. 2D-shear wave elastography (SWE) PLUS and viscosity plane-wave ultrasound (Vi PLUS) have emerged as novel techniques that promise to offer improved stiffness measures due processing algorithms. Methods: We performed cross-sectional study 50 kidney transplanted patients (16 women, 34 men; mean age 47.5 ± 12.5; estimated glomerular filtration rate (eGFR) by Chronic Kidney Disease Epidemiology...

To analyze the relationship between shear wave velocity in kidney measured by point elastography using Virtual Touch Quantification (VTQ) (Siemens Acuson S2000) and histological parameters obtained from renal biopsies, patients with chronic glomerulonephritis (CGN).The study group included 20 (mean age 47.95±13.59 years) different types of CGN, that had underwent biopsy 57 normal controls 38.07±17.32 years). In all patients, five valid stiffness measurements were each kidney, patient lateral...

Point shear wave elastography is a quantitative ultrasound-based imaging method used in the assessment of renal disease. Among point elastographic options, 2 techniques have been studied considerably: Virtual Touch quantification (VTQ; Siemens AG, Erlangen, Germany) and ElastPQ (EPQ; Philips Healthcare, Bothell, WA). Both rely on tissue response to an acoustic beam generated by ultrasound transducer. The data VTQ are more extensive, whereas EPQ has less thus far kidneys. This study aimed...

Background: Changing the term/concept of non-alcoholic fatty liver disease (NAFLD) to metabolic dysfunction associated (MAFLD) may broaden pathological definition that can include chronic renal involvement, and, possibly, changes kidney disease's (CKD's) epidemiological association with disease, because CKD is disorders and almost all patients present some form an atherogenic dyslipidemia. Our study explores relationship between MAFLD using Transient Elastography (TE) a Controlled Attenuated...

Klotho is found in two forms: a transmembrane form and soluble (s-Klotho). In order to be excreted, s-Klotho, that too large filtered, will probably reach the proximal convoluted tubule by transcytosis process. The aim of our study was show relationship between levels s-Klotho tubular injury patients with diabetic kidney disease (DKD), using as marker molecule-1 (KIM-1). Our included 63 DKD (stages 1–5, mean eGFR 65.15 ± 32.45 ml/min) age 58.13 12 years. all we determined serum of: KIM-1...

Abstract Left ventricular (LV) structure and function anomalies are frequent during the CKD continuum associated with increased risk of mortality. Cross section longitudinal ultrasound data available for advanced transition to ESKD. Less information is about LV changes stable, long-term hemodialysis (HD) treatment. All stable HD patients from 9 centers (1034 patients, 671 males, age 58.71 ± 12.94 years) have been enrolled in January 2015. The cohort was followed-up 4 years, kidney...

The preservation of complication-free arterio-venous fistulas (AVF) for long-term hemodialysis (HD) use is associated with better overall patient outcomes, which why this a current goal in any HD center. Point-of-care ultrasound (POCUS) in-center AVF assessment has proven its benefits the identification vascular access (VA) complications and as an additional tool to avoid blind cannulation. study aims assess change nurses’ perceptions regarding POCUS nursing staff anonymously answered Likert...

The importance of identifying mortality biomarkers in chronic kidney disease (CKD), and especially patients treated with hemodialysis (HD), has become evident. In addition to being a marker tubulointerstitial injury, plasma injury molecule-1 (KIM-1) been mentioned regard HD as risk for cardiovascular (CV) coronary artery calcification. aim this study was assess the level KIM-1 (CVD) CKD5-HD (patients CKD stage G5D hemodialysis).

(1) Background: Vitamin K deficiency is a common feature of chronic kidney disease (CKD), leading to impaired bone quality and increased risk vascular calcifications. A method indirectly measure status measuring the blood level dependent proteins (VKDP)- osteocalcin (OC) matrix GLA protein (MGP). The aim this study correlate OC MGP with markers CKD mineral disorder (CKD-MBD). (2) Methods: We conducted single-center cross-sectional that included 45 G5D patients measured biochemistry, complete...

(1) Background: Vitamin K deficiency is a common feature of chronic kidney disease (CKD), leading to impaired bone quality and an increased risk vascular calcifications. A method indirectly assess the vitamin status measuring blood level K-dependent proteins (VKDP): osteocalcin (OC) matrix GLA protein (MGP). The aim this study correlate total OC inactive MGP (dp-uc MGP) with markers CKD mineral disorder (CKD-MBD). (2) Methods: We conducted single-center cross-sectional that included 45 G5D...

The standard method for identification of male fertility status is a semen analysis. This performed in and pathology laboratories accredited by different bodies the UK such as HFEA or UKAS, based on whether they perform licenced clinical treatment diagnostic testing. WHO laboratory analysis criteria provide most comprehensive guidance best practice, yet this not strictly adhered to. Our objective was to determine any differences analyses between UK, regulatory body are registered with. A...

(1) Background: Arterio-venous fistulas (AVFs) are considered the gold-standard vascular access (VA) in patients on maintenance hemodialysis (HD) therapy. AVF calcifications represent a less studied VA related complication, even though HD at higher risk for extraosseous calcifications. The aim of this study is to assess prevalence and factors calcifications, as well 5-year impact functionality overall mortality. (2) Methods: We conducted prospective including 161 At baseline, we collected...

Background/Objectives: Vitamin K deficiency in chronic kidney disease (CKD) could potentially occur due to multiple factors, leading an increased risk of vascular and valvular calcifications. status can be indirectly assessed by measuring the blood levels vitamin K-dependent proteins (VKDPs), such as matrix GLA protein (MGP). This study aims examine relationship between inactive MGP (dp-uc MGP) presence calcifications, well its association with mortality hemodialysis patients. Methods: We...

Purpose: The results published so far regarding elastography of the kidney (mainly point shear wave speed measurements) are not always consistent. present study aims to evaluate another elastographic method (2D-SWE, Aixplorer, Supersonic Imagine), performed independently in two centers.

Purpose: Different types of point shear wave elastography (Siemens-Virtual touch quantification, Phillips- Elastography quantification) have been previously used to assess the kidneys. In present study we aim use for first time a new method: 2D-SWE.GE (LogiqE9, GE Healthcare, Chalfont St Giles-UK), in order analyze how many measurements are needed and what factors influence kidney speed (KSWS) normal subjects.